Review: Prilosec and Flagyl drug interactions
This review analyzes the interactions between Prilosec and Flagyl. It is created by eHealthMe based on 2,474 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Prilosec (latest outcomes from 61,423 users) has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease.
Flagyl (latest outcomes from 10,449 users) has active ingredients of metronidazole. It is often used in vaginitis bacterial.
On Mar, 1, 2014: 2,474 people who reported to have interactions when taking Prilosec, Flagyl are studied
Drug combinations in study:
- Prilosec (omeprazole)
- Flagyl (metronidazole)
Most common interactions experienced by people in the use of Prilosec, Flagyl:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Dyspnoea (difficult or laboured respiration)||597|
|Nausea (feeling of having an urge to vomit)||355|
|Anaemia (lack of blood)||333|
|Fatigue (feeling of tiredness)||316|
|Osteonecrosis Of Jaw (death of bone of jaw)||284|
Most common interactions experienced by people in long term use of Prilosec, Flagyl:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)||4|
|Blood Creatinine Increased||2|
|Neuropathy Peripheral (surface nerve damage)||2|
|Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)||2|
|General Physical Health Deterioration (weak health status)||2|
|Intervertebral Disc Protrusion (spinal disc protrusion)||2|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Crohn's disease
- Multiple myeloma
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Prilosec (omeprazole) is often used to treat gastroesophageal reflux disease. Flagyl (metronidazole) is often used to treat vaginitis bacterial. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Prilosec is used in:
- Flagyl is used in:
Other drugs that are used to treat the same conditions:
- Prilosec alternatives:
- Flagyl alternatives:
Comments from related studies:
From this study (12 months ago):
My 5 year old daughter was prescribed with Amoxicillin, Metronidazole and Omeprazole after being diagnosed with hyplory some stomach bacteria. She was on the treatment for 7 days. She has not been the same. She started hallucinating, not sleeping at night, anxiety, depression symptoms’, name it. She has been behaving like someone with mental illness. Loss of concentration. She was referred to A&E paediatrics and most of the doctors had no clue what was wrong. Only one consultant agreed to the effect of the drugs. It has been 3 weeks and there is improvement.
Koren on Jan, 24, 2013:
You should read about PANDAS. You are describing all the hallmark symptoms. Children with this disorder have an incorrect autoimmune response to Strep, but often other infection trigger the same response which ultimately attacks the basal ganglia of the brain. Most likely, it was not the antibiotic that caused your daughter to behave like she was "suddenly" mentally ill. Instead, I would explore that her immune system was triggered by the infection. The reaction can take weeks or days to set in motion - which can be misleading to parents.
Carol on Feb, 4, 2013:
My daughter also had problems when on amoxicillin and they were NOT related to being sick. She'd had a deep filling and the dentist was trying to prevent an infection. The day before starting it, she had an amazing gymnastics meet. By the time she was on it a few days, she was behind the music and the other girls. She got in trouble at school and in the after school program when she normally does not. Her behavior at home was terrible. She failed a math exam that covered easy material she knew well. She will not be taking it again unless there are no other options. Metronidazole can cause peripheral nerve damage so I wouldn't be surprised if it affected brain function.
Friendly person on Mar, 14, 2013:
It could be a case of PANDAS. Unfortunatelt there is no cure but good news is it seems to fade over time. Try a google search for "pandas amoxicillin"
kathy on Mar, 20, 2013:
i also had h pylori its the flagyl side effect it has to work it out of her system eat healthy no eating out i contracted by not eating my food i ate others and fast foods dont no more flagyl can cause mental hyperness and disorder
i hope she is better
need answers on Apr, 2, 2013:
My 7yr old daughter had a reaction after 5 doses of amoxicllin. She was unable to stop moving her legs in bed. The next day she was hyperactive, and then for the next 5 days she had 'meltdowns' which are not characteristic of her. She had a worse reaction to zyrtec and benadryl the year before...she could not stop moving, she was uncomfortable, cried a lot, wet the bed, and was nervous.
It seems as though her system became hypersensitive after the zyrtec reaction.
Does anyone know of a doctor familiar with these reactions?
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You may be interested at these reviews (what is this?):
- By Dugald: Flagl helped my depression
After taking Flagl for two weeks (Two per day) My depression vanished. It is now three months since I had a depression episode. Thank God for the doctor who prescribed it he saved my life. Thank you Flagl
- By novzchan: Tonsillitis for 1 week
i suffered tonsillitisfor a week. and i lose my weight coz i kept on vomiting. we rushed into my doctor's clinic. he advised me to stay in the hospital for 3 days cause my tonsillitis was really severe. he prescribed me cefuroxime axetil via IV for further absorption and omeprazole via IV for my sto ...
- By Misstiff: Too much sleep/sleeping past 12+ hours
Caused me to sleep and to the point where I slept 12+ hours and still didn't want to wake up
Recent related drug studies:
- A study of drug interactions between Amoxicillin, Metronidazole, Omeprazole for a patient with Helicobacter Pylori, Helicobacter Pylori Infection. The patient has Mental Disorder
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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