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Review: Promethazine With Codeine and Benadryl

This review analyzes the effectiveness and drug interactions between Promethazine With Codeine and Benadryl. It is created by eHealthMe based on 197 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 5, 2014: 197 people who reported to have interactions when taking Promethazine With Codeine, Benadryl are studied

Trend of Promethazine With Codeine, Benadryl's drug interactions, side effects and effectiveness reports (3566211)

Drug combinations in study:
- Promethazine With Codeine (codeine phosphate; promethazine hydrochloride)
- Benadryl (diphenhydramine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Promethazine With Codeine, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Vomiting107
Arthralgia (joint pain)96
Nausea (feeling of having an urge to vomit)82
Insomnia (sleeplessness)80
Back Pain76
Pain76
Fatigue (feeling of tiredness)68
Headache (pain in head)65
Depression62
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)58

Most common interactions experienced by people in long term use of Promethazine With Codeine, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety2
Intentional Overdose2
Hallucination, Auditory (perceiving sounds without auditory stimulus)2
Depression2
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)2
Aggression2
Suicide Attempt2
Suicidal Ideation2

How effective are the drugs:

n/a

Top conditions involved for these people * :

  1. Pain
  2. Prophylaxis
  3. Insomnia
  4. Abdominal pain
  5. Depression

Top co-used drugs for these people * :

  1. Diphenhydramine hcl
  2. Acetaminophen
  3. Digoxin
  4. Seroquel
  5. Coumadin

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Complete drug side effects:

On eHealthMe, Promethazine With Codeine (codeine phosphate; promethazine hydrochloride) is often used to treat cough. Benadryl (diphenhydramine hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Can you answer these questions (what is this?):

More questions for: Benadryl, Promethazine With Codeine

You may be interested at these reviews (what is this?):

  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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