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Review: Provigil and Nuvigil





Summary: drug interactions are reported among people who take Provigil and Nuvigil together.

This review analyzes the effectiveness and drug interactions between Provigil and Nuvigil. It is created by eHealthMe based on reports of 175 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Provigil and Nuvigil >>>

What are the drugs

Provigil has active ingredients of modafinil. It is often used in narcolepsy. (latest outcomes from Provigil 10,275 users)

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. (latest outcomes from Nuvigil 4,396 users)

On Dec, 19, 2014: 175 people who take Provigil, Nuvigil are studied

Provigil, Nuvigil outcomes

Drug combinations in study:
- Provigil (modafinil)
- Nuvigil (armodafinil)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Provigil is effectiven/a0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
n/an/an/an/an/a
Nuvigil is effectiven/a100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveDrug IneffectiveNauseaDrug IneffectiveCheilitisDeathn/aDrug Ineffective
AnxietyAngerHeadacheHeadacheTherapeutic Response UnexpectedDeep Vein ThrombosisHeadache
DysarthriaDecreased AppetiteDepressionPain In ExtremitySpeech DisorderPulmonary EmbolismNausea
Speech DisorderHeadacheDrug IneffectiveDepressionSwollen TongueCardiovascular DisorderDizziness
DysphoniaPain In ExtremityDecreased AppetiteNauseaAphthous StomatitisDrug IneffectiveAnxiety
HeadacheNauseaAngerDecreased AppetiteLip SwellingTremorRash
Skin HaemorrhageDepressionPain In ExtremityAngerUrinary IncontinenceOropharyngeal PainMigraine
Sensorimotor DisorderRash GeneralisedIrritabilityRash GeneralisedDysphoniaChest PainFatigue
General Physical Health DeteriorationAnxietyBronchitisEye PainDysarthriaDyspnoeaAbdominal Pain Upper
Oropharyngeal PainDry MouthUrinary Tract InfectionAlopeciaOesophageal SpasmChest Pain

Drug effectiveness by gender :

FemaleMale
Provigil is effective33.33%
(1 of 3 people)
n/a
Nuvigil is effective66.67%
(2 of 3 people)
n/a

Most common drug interactions by gender * :

FemaleMale
HeadacheDrug Ineffective
NauseaDepression
DizzinessDeath
BronchitisNausea
Urinary Tract InfectionDecreased Appetite
Drug IneffectiveAnxiety
Abdominal Pain UpperHeadache
MigraineAnger
Upper Respiratory Tract InfectionDyspnoea
Deep Vein ThrombosisPain In Extremity

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Provigil is effectiven/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 5 people)
100.00%
(1 of 1 people)
n/an/a
Nuvigil is effectiven/an/an/a0.00%
(0 of 1 people)
20.00%
(1 of 5 people)
100.00%
(1 of 1 people)
n/an/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aHeadachePulmonary EmbolismConfusional StateFlushingUpper Respiratory Tract InfectionRash
NauseaDeep Vein ThrombosisConvulsionBack PainNauseaGastrooesophageal Reflux Disease
Pain In ExtremityDyspnoeaDecreased AppetiteHeadacheSinusitisDizziness
Drug IneffectiveChest PainHeadacheMemory ImpairmentCoughDrug Ineffective
AngerAnaemiaDeep Vein ThrombosisPyrexiaUrinary Tract InfectionSomnolence
Decreased AppetiteBrain HerniationDysarthriaDisorientationBronchitisFamily Stress
DepressionBrain DeathPanic ReactionEye PruritusHeadacheBlood Copper Decreased
RhabdomyolysisFatigueNauseaMuscle StrainDizzinessStaphylococcus Test Positive
Musculoskeletal StiffnessFatigueHip FractureGait DisturbanceArthralgia
Dental CariesDepressed MoodNauseaNuclear Magnetic Resonance Imaging Brain AbnormalFibromyalgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Provigil and Nuvigil?

You are not alone! Join a related mobile support group:
- support group for people who take Provigil and Nuvigil
- support group for people who take Nuvigil
- support group for people who take Provigil

Can you answer these questions (Ask a question):

  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • What side effects from nuvigil and cymbalta creating seretonin syndrome? (2 answers)
    My dr thinks that all the drugs I'm on are causing sedition syndrome. But I have t seen where a symptom was red flushed skin?
  • Does one ever get their memory back after discontinueing the tysabri?
    vesicare 10mg x1 bupropion 150mg x1
    lisinopril 5mg as needed bupropion 300mg x1
    fluoxetine 20mg x1 alprazolam 0.5mg - bedtime
    vigil 250mg x1 melatonin 3mg - bedtime
    aubagio 14mg. x1 diphenhydramine 50mg - bedtime
    carvedilol 6.25mg x1 aspirin 500mg - bedtime
    bupropion 300mg x1
    baclofen 10mg as needed DO I NEED ANYTHING ELSE?
    alprazolam 0.5mg
    benedryl 50mg.
    bupropion 300mg
  • Is there a connection between narcolepsy and neurofibromatosis
    Hi ,My name is Pauline Newman I live in Adelaide,South Australia,I have NF1 & NF2,I am 5th generation carrier of the NF Gene,I have literally thousands of lumps,bumps & café au-lait marks all over my body.My question is are NF1 & 2,cause Narcolepsy or EDS, I have also recently had an MRI & ultra sound which has shown up a Plexiform NF, I am in constant pain because of scoliosis,and I am Totally wheelchair reliant, I have 2 Harrington rods alongside my spine & have had a T4-L4 fusion & T12 osteotomy, As a result of my spinal condition I have Rhuematoind Arthritis,fibromyalgia and low vitamin D levels & iron deficiency.Is it possible that these medical conditions are all linked to NF?


    Thankyou
    Sincerelly
    Pauline Newman
    20A Shearer Ave Seacombe Gardens.. SA 5047
  • Will taking nuvigil effect my sperm count?
    I am just wondering if my meds affect my sperm count. My wife and I are trying to have a child and we haven't been successful.

More questions for: Nuvigil, Provigil

You may be interested at these reviews (Write a review):

  • Aggression with law enforcement officers who use provigil
    I'm a former police officer. I say former because on the second day of ever taking provigil, I flipped out and kicked a handcuffed arestee. After 10 years of being an award winning police officer I totally lost it after taking this drug. needless to say, I immediately quit taking the pill; however, my career is over. Has anyone ever heard of something like this happening? Do I have any rights?
  • Idiopathic insomnolence (1 response)
    So...

    In 1997 I was diagnosed with Narcolepsy with an intolerance to Dexamp(hetamine) tablets.

    After 3 years of nose operations, and sleep tests to remove other potential issues (lung problems or apnoea) I have finally been re-diagnosed (2013) with idiopathic insomnolence.

    Modaphinil caused a reaction of insane nausea, pains behind the eyes, dizzy spells, with no real change in blood pressure.

    Dexamphetamine was erratic (on recent retrial) with extremes causing dizzy spells and slow progressive drop in BP over 3 weeks from average 125/75 to 105/60. Occasionally it would wake my body up but my brain would be slow to follow, and the conflict would take me to the cleaners for the next two days.

    I was diagnosed with IgAN in 2004, and have progressive idiopathic neuropathy in my feet since 2011.

    The sleep specialist wants me to try Klacid (clarithromycin) as it has reportedly caused insomnia on a regular basis. I've not yet agreed.

    That's me in a nutshell.

    To many idiopathics and drug rejections.

    Somebody has not got their finger on the pulse, but no idea who yet.

    Jus thought I'd throw this out there in case anyone else is having difficulties aswell.

    Cheers !
  • Libido increase with xyrem (2 responses)
    Although it appears by my med list that I am a train wreck, its quite the contrary. Now that my migraine headaches have been controlled by Inderal & Cymbalta and my thyroid is under control, the only thing left to do was to fall asleep at the oddest times, which progressed to not being able to stand while I fought to stay awake. Not good when you have to work.

    After multitudes of sleep studies and a reluctance to take Xyrem, it was my only option if I wanted to keep working. Well Xyrem causes weight loss and I was already pretty small and now I have lost 9 more pounds (under 110) and have the libido of an 18 yr old man. I am a woman in my late 40s with a whole lot of children and a full time job. I have been on Xyrem going on 3 months now and if my libido is getting stronger each week. Initially it was only after I took my 1st dose that I had the need for intimacy, but now I sit at work in the mid-afternoon and can not think of anything else. The Xyrem seems to direct blood & warmth to certain regions of the body, much like Viagra does to a man to produce an erection. I have to think about eating not to lose anymore weight, but the urge to be intimate is undeniably strong and extremely distracting. Some nights when I can not get enough I have even resorted to looking at inappropriate pictures on the internet. This is NOT ME!!! I don't do that! My husband's friends are envious, but even he is getting exhausted and sore. The Xyrem may have saved my marriage for now, but I now look at other men like they are all objects for my fulfillment- ewww! I hope my libido dies down some soon because stopping the xyrem means falling asleep at work I will lose my job. Staying on it however, I certainly risk having a fling just because I feel like a nymphomaniac with "I can't get no satisfaction" playing over and over in my head.

More reviews for: Nuvigil, Provigil

Complete drug side effects:

On eHealthMe, Provigil (modafinil) is often used to treat narcolepsy. Nuvigil (armodafinil) is often used to treat narcolepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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