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Review: Trazodone and Prozac





Summary: drug interactions are reported among people who take Trazodone and Prozac together.

This review analyzes the effectiveness and drug interactions between Trazodone and Prozac. It is created by eHealthMe based on reports of 3,412 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Trazodone and Prozac >>>

What are the drugs

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from Trazodone hydrochloride 6,611 users)

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. (view latest outcomes from 42,269 users)

On Dec, 15, 2014: 3,411 people who take Trazodone Hydrochloride, Prozac are studied

Trazodone Hydrochloride, Prozac outcomes

Drug combinations in study:
- Trazodone Hydrochloride (trazodone hydrochloride)
- Prozac (fluoxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Trazodone Hydrochloride is effective19.05%
(4 of 21 people)
36.84%
(7 of 19 people)
47.06%
(8 of 17 people)
42.86%
(9 of 21 people)
57.14%
(16 of 28 people)
55.00%
(11 of 20 people)
73.33%
(11 of 15 people)
n/a
Prozac is effective12.50%
(2 of 16 people)
27.27%
(6 of 22 people)
33.33%
(5 of 15 people)
38.10%
(8 of 21 people)
45.83%
(11 of 24 people)
36.84%
(7 of 19 people)
46.43%
(13 of 28 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ArthralgiaType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDepressionNausea
DepressionNauseaNauseaType 2 Diabetes MellitusObesityWeight IncreasedFatigueType 2 Diabetes Mellitus
Disturbance In AttentionBack PainDrug Exposure During PregnancyPainBlood Cholesterol IncreasedDiabetes MellitusMemory ImpairmentDiabetes Mellitus
InsomniaObesityDiabetic NeuropathyBlood Cholesterol IncreasedBlood Triglycerides IncreasedDiabetes Mellitus Inadequate ControlDepressed MoodDepression
NauseaDiabetic KetoacidosisBlood Triglycerides IncreasedObesityDepressionAnxietyVision BlurredAnxiety
MalaisePainStillbirthBladder DisorderChest PainObesityPanic AttackPain
Pharyngolaryngeal PainAgitationHypercholesterolaemiaBlood Triglycerides IncreasedOsteoporosisPainVictim Of CrimeFatigue
AngerMuscle SpasmsMultiple AllergiesDepressionWeight IncreasedTardive DyskinesiaAngerHeadache
Blood Creatine Phosphokinase IncreasedHyperglycaemiaDiabetes MellitusHysterectomyRib FractureDepressionStressDyspnoea
Neuropathy PeripheralWeight IncreasedSinusitisInflammationPerirectal AbscessGallbladder DisorderSomnolenceFall

Drug effectiveness by gender :

FemaleMale
Trazodone Hydrochloride is effective50.94%
(54 of 106 people)
34.29%
(12 of 35 people)
Prozac is effective39.81%
(43 of 108 people)
25.00%
(9 of 36 people)

Most common drug interactions by gender * :

FemaleMale
NauseaAnxiety
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
Diabetes MellitusDiabetes Mellitus
DepressionDepression
PainNausea
HeadacheFatigue
AnxietyPain
FatigueSuicidal Ideation
DyspnoeaFall
Weight IncreasedInsomnia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Trazodone Hydrochloride is effectiven/a0.00%
(0 of 2 people)
33.33%
(1 of 3 people)
18.75%
(9 of 48 people)
35.56%
(16 of 45 people)
23.46%
(19 of 81 people)
25.45%
(14 of 55 people)
25.00%
(7 of 28 people)
Prozac is effectiven/a0.00%
(0 of 2 people)
6.67%
(1 of 15 people)
14.81%
(8 of 54 people)
26.09%
(12 of 46 people)
15.38%
(12 of 78 people)
25.45%
(14 of 55 people)
16.67%
(5 of 30 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes MellitusElectrocardiogram Qt ProlongedAggressionDiabetes MellitusType 2 Diabetes MellitusDiabetes MellitusNauseaPain
AggressionBipolar DisorderSuicidal IdeationType 2 Diabetes MellitusDiabetes MellitusType 2 Diabetes MellitusDepressionFatigue
Tardive DyskinesiaRespiratory Failure (excl Neonatal)Suicide AttemptDizzinessNauseaNauseaType 2 Diabetes MellitusAnxiety
PancreatitisPulse AbsentWeight IncreasedVomitingAnxietyDyspnoeaFallAsthenia
Congenital Diaphragmatic HerniaInsomniaNauseaAbdominal Pain UpperDepressionHeadacheHeadacheFall
ConvulsionLeft Ventricular HypertrophyPersonality ChangeWeight IncreasedWeight IncreasedFatiguePainDiarrhoea
Lung Disorder NosAggressionAngerSuicidal IdeationDrug Withdrawal SyndromeDepressionPain In ExtremityDyspnoea
Peritoneal EffusionSedationAgitationPancreatitisPainChest PainAnxietyHeadache
Pleural EffusionWeight IncreasedScreamingDepressionDrug DependenceAnxietyDiabetes MellitusConstipation
Pelvic Fluid CollectionDrug IneffectivePsychomotor HyperactivityDyspnoeaHeadacheWeight IncreasedFatigueSpinal Osteoarthritis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Trazodone and Prozac?

You are not alone! Join a related mobile support group:
- support group for people who take Trazodone and Prozac
- support group for people who take Prozac
- support group for people who take Trazodone Hydrochloride

Can you answer these questions (Ask a question):

  • I'm starting 7.5 mg remeron tonight , how can i expect to feal in the morning? (1 answer)
    Long period of depression desperate to find something that will work quik and give me some energy.
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Do you have issues snoring from testosterone
    I was in an IED explosion in Afghanistan, had a TRAUMATIC BRAIN INJURY, 2005.JULY 28THlevels were extremely low. my V.A. doctor put me on testesterone 2011 BREAST CANCER, AUG 11TH 2012 HIT AND RUN ON MY MOTORCYCLE. DUE TO all the pain meds chemo, etcetera. MY testosterone. At first it was the best thing that had happened to me since I woke up in the hospital now I snore like a drunk Marined. and the culprit is the testosterone. I need to save my marriage and do something aboot this. any ideas what I can do
  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?
  • My sister has been taking depakote cogentin and geodon and suffers with great memory loss inability to carry on a conversation and drops things all the time is this the effect of these drugs? (1 answer)
    Sister takes over 16 perscriptions but the ones mentioned are severe.. due to being bi-polar, and severe agoraphobia and anxiety with depression..is this now her life? Not being able to fully comprehend or remember anything? Dropping things and falling when under the full impact of this medication? I either need to get some acceptance or find answers to the effects this medicine is causing..afraid to change up her medicines but needless to say I am worried...

More questions for: Prozac, Trazodone Hydrochloride

You may be interested at these reviews (Write a review):

  • A life of depression and fatigue
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • Lorazepam nearly killed me during cancer treatment
    Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first normal bowel movement in over 2 years. Stomach so damaged by Lorazepam that I have absolutely no appetite. I force myself to eat. Neuropathy in hands nearly gone. Feet are better but slower. Lymphedema that appeared after one year on Lorazepam is now gone. I have full range of motion.
  • Prescribed drugs side effect (1 response)
    I have been on these 2 drugs (Gabapentin and Baclofen) prescribed by my gp for osteoarthritis and nerve damage in my full back.Now also suffering from the grief of losing my beloved companion Harvey (dog),I was diagnosed with deep depression. I was given fluoxetine and have been taking this for almost 4 weeks (along with the other 2 meds) and today I have a very sore tongue and it has been white for a number of days,i am going to the pharmacy tomorrow to seek some advice as I am not sure I should be taking all these together? As I am on the highest dose of depression tablets with the fluoxetine I feel it is unsafe to take with the other 2 as the baclofen can also be used to treat certain types of depression. But I can not do without either and as I am allergic to codeine I am pretty much stuck.
  • Patients having false positives while on remeron
    I have had a few patients complain they are failing drug tests for Amphetamines while on remeron, and have claimed to have not used any type of Amphetamine or any (Mixed Salts). These patients are all or were on probation, parole, or under some stipulation. Iv realized most of these patients are taking another psych med. The list consists of insomnia meds such as Ambien(zolpidem), Sonata(zaleplon),Lunesta(eszopiclone). Also the Anti-Depressants Lexapro (escitalopram)and Prozac (fluoxetine). One of my patients was on Diazepam (Valium). I have switched medicines, particularly the Ambien, Lexapro, and Prozac have reversed the false negative. I prescribe many of my patients remeron. I'm a big believer in its effects on my patients moods and everyday depression. I have heard this happening before, but this was the first time I have ever had this happen to one of my own patients.(These were 5 separate patients in the span of 16 months) Of course none of these patients were criminalized based on lab results, but the issue still lies there. I know this is common for a lot of script meds to give false positives for narcotics. This is just obviously one I am putting out there. Let me know if anyone has experienced something similar.
  • Hit and miss sleep with dextroamphetamine
    Started drug 2 months ago and have seen an improvement in my focus. Ziprosidone for my depression causes me to get dead tired by 7 pm. Once I started taking Dextroamphetamine I started having insomnia 2 times a week. I think I would rather sleep early than stay up all night and then try and stay awake at work. So many drugs and even more side effects. Also Trazadone is no help for getting me to sleep. The only good side affect I have seen is I am down 26 pounds.

More reviews for: Prozac, Trazodone Hydrochloride

Comments from related studies:

  • From this study (5 months ago):

  • never done full panel of hormones; cortisol flatlined 5 years ago now too high; testing also showed high estrogen levels for peri-menopausal female

    Reply

  • From this study (10 months ago):

  • UNCONTROLLABLE ANGER

    Reply

  • From this study (10 months ago):

  • Pervasive developmental disorder...autism...unexplained g.i. Issues with multiple procedures only finding inflammation...prescribed sucralfate after severe vomiting which seemed to help for awhile, but cycle seems to be starting all over again...vomits often after eating

    Reply

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Complete drug side effects:

On eHealthMe, Trazodone Hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Prozac (fluoxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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