From FDA reports: drug interactions between Seroquel and Xanax
This is a real world study of Seroquel and Xanax drug interactions. The study is created by eHealthMe based on 4,414 reports from FDA.
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What are the drugs
Seroquel has active ingredients of quetiapine fumarate. It is used in bipolar disorder, insomnia, bipolar i disorder, depression, sleep disorder, stress and anxiety.
Xanax has active ingredients of alprazolam. It is used in stress and anxiety, generalized anxiety disorder, panic disorder, insomnia, panic attack, sleep disorder.
On May, 23, 2013: 4,414 people who reported to have interactions when taking Seroquel, Xanax are studied

Drug combinations in study:
- Seroquel (quetiapine fumarate)
- Xanax (alprazolam)
Most common interactions experienced by people in the use of Seroquel, Xanax:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diabetes Mellitus | 1,552 |
| 2 | Type 2 Diabetes Mellitus | 1,393 |
| 3 | Anxiety | 1,029 |
| 4 | Blood Cholesterol Increased | 861 |
| 5 | Depression | 519 |
| 6 | Insomnia | 461 |
| 7 | Weight Increased | 405 |
| 8 | Nausea | 318 |
| 9 | Pain | 315 |
| 10 | Headache | 307 |
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Most common interactions experienced by people in long term use of Seroquel, Xanax:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Type 2 Diabetes Mellitus | 795 |
| 2 | Diabetes Mellitus | 708 |
| 3 | Blood Cholesterol Increased | 409 |
| 4 | Hyperglycaemia | 210 |
| 5 | Obesity | 137 |
| 6 | Pancreatitis | 137 |
| 7 | Diabetes Mellitus Inadequate Control | 117 |
| 8 | Diabetic Neuropathy | 110 |
| 9 | Weight Increased | 101 |
| 10 | Insomnia | 99 |
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Top conditions involved for these people * :
- Depression
- Anxiety
- Bipolar disorder
- Sleep disorder
- Pain
Top co-used drugs for these people * :
- Risperdal
- Zyprexa
- Ambien
- Lexapro
- Zoloft
* Approximation only. Some reports may have incomplete information.
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Side effects in real world:
On eHealthMe, Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
Other drugs that are used to treat the same conditions:
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
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