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Review: Seroquel and Cyclobenzaprine





Summary: drug interactions are reported among people who take Seroquel and Cyclobenzaprine together.

This review analyzes the effectiveness and drug interactions between Seroquel and Cyclobenzaprine. It is created by eHealthMe based on reports of 1,407 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Seroquel and Cyclobenzaprine >>>

What are the drugs

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 79,098 users)

Cyclobenzaprine hydrochloride has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Cyclobenzaprine hydrochloride 2,373 users)

On Nov, 25, 2014: 1,407 people who take Seroquel, Cyclobenzaprine Hydrochloride are studied

Seroquel, Cyclobenzaprine Hydrochloride outcomes

Drug combinations in study:
- Seroquel (quetiapine fumarate)
- Cyclobenzaprine Hydrochloride (cyclobenzaprine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Seroquel is effective50.00%
(4 of 8 people)
53.85%
(7 of 13 people)
57.14%
(4 of 7 people)
33.33%
(2 of 6 people)
60.00%
(6 of 10 people)
33.33%
(2 of 6 people)
100.00%
(2 of 2 people)
n/a
Cyclobenzaprine Hydrochloride is effective15.38%
(2 of 13 people)
36.36%
(4 of 11 people)
37.50%
(3 of 8 people)
28.57%
(2 of 7 people)
0.00%
(0 of 1 people)
33.33%
(2 of 6 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Type 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes Mellitus
InsomniaDiabetes MellitusHeadacheChest PainDiabetes MellitusDiabetes MellitusBlood Cholesterol IncreasedType 2 Diabetes Mellitus
DepressionHyperlipidaemiaMulti-organ FailureBack PainDiabetic NeuropathyDiabetes Mellitus Inadequate ControlHyperlipidaemiaBack Pain
Suicide AttemptDiabetic NeuropathyVertigoAsthmaHyperglycaemiaBlood Cholesterol IncreasedPancreatitisAnxiety
Diabetes MellitusBlood Cholesterol IncreasedNeutropeniaSleep Apnoea SyndromeObesityBack PainUrinary Tract InfectionPain
Suicidal IdeationDiabetes Mellitus Inadequate ControlSeptic ShockDiabetes MellitusBlood Cholesterol IncreasedHyperlipidaemiaOral CandidiasisHeadache
DyspnoeaObesityWeight IncreasedHypertensionBack PainDiabetic KetoacidosisMetabolic AcidosisDepression
DizzinessSyncopeInsomniaHeadacheSuicidal IdeationDiabetic NeuropathyMalaiseInsomnia
HeadacheDrug IneffectiveBlood Triglycerides IncreasedHyperlipidaemiaHyperlipidaemiaPancreatitisLethargyHypertension
AggressionParaesthesiaHyperglycaemiaAnxietyDiabetes Mellitus Inadequate ControlChest PainSwellingDiabetic Neuropathy

Drug effectiveness by gender :

FemaleMale
Seroquel is effective45.00%
(18 of 40 people)
72.73%
(8 of 11 people)
Cyclobenzaprine Hydrochloride is effective28.95%
(11 of 38 people)
36.36%
(4 of 11 people)

Most common drug interactions by gender * :

FemaleMale
Diabetes MellitusDiabetes Mellitus
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
Back PainDepression
HeadacheInsomnia
AnxietyDiabetes Mellitus Inadequate Control
PainChest Pain
DepressionSuicidal Ideation
ArthralgiaPain
Weight IncreasedAnxiety
HypertensionNeuropathy Peripheral

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Seroquel is effectiven/an/a100.00%
(1 of 1 people)
45.45%
(5 of 11 people)
17.39%
(8 of 46 people)
21.21%
(7 of 33 people)
12.12%
(4 of 33 people)
100.00%
(1 of 1 people)
Cyclobenzaprine Hydrochloride is effectiven/an/a100.00%
(1 of 1 people)
18.18%
(2 of 11 people)
11.63%
(5 of 43 people)
6.06%
(2 of 33 people)
12.12%
(4 of 33 people)
100.00%
(1 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes Mellitusn/aDiabetes MellitusInsomniaDiabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes Mellitus
Type 2 Diabetes MellitusDiabetic KetoacidosisDiabetes MellitusType 2 Diabetes MellitusDiabetes MellitusDiabetes MellitusType 2 Diabetes Mellitus
ObesityDiabetic ComplicationType 2 Diabetes MellitusCompleted SuicideDiabetic NeuropathyArthralgiaFall
PancreatitisHepatic SteatosisBronchitisDepressionBack PainBack PainNeuroleptic Malignant Syndrome
GastritisCongenital Ectodermal DysplasiaBack PainArthralgiaDiabetes Mellitus Inadequate ControlFatigueRenal Failure
Blood Cholesterol IncreasedCardio-respiratory ArrestSuicidal IdeationHypertensionChest PainAnxietyAnxiety
Pulmonary CongestionBlood Cholesterol IncreasedWeight IncreasedHeadachePainRespiratory Failure
Pulmonary OedemaUrinary Tract InfectionHeadacheWeight IncreasedHeadacheFatigue
FearNauseaAnxietyNeuropathy PeripheralNauseaContusion
PainInjuryDiabetes Mellitus Inadequate ControlAnxietyFibromyalgiaPain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Seroquel and Cyclobenzaprine?

You are not alone! Join a related mobile support group:
- support group for people who take Seroquel and Cyclobenzaprine
- support group for people who take Cyclobenzaprine Hydrochloride
- support group for people who take Seroquel

Can you answer these questions (Ask a question):

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  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • What is the reaction to vivitrol and ritalin?
    25 year old client in early recovery from opioid dependence takes ritalin and seroquel and wants to add vivitrol. What are the risks and side effects?
  • Does anyone have experience of taking the supplement gaba with seroquel/quetiapine at night to aid sleep?. taking quetiapine 150 mg gives inconsistent sleep.
    With seroquel my sleep is inconsistent and if I have a bad night's sleep, I don't just feel tired, I feel breathless, headache, strange sensations, as if I haven't slept off side effects. It can make me feel relaxed when I take it but not sleepy.
  • Why would i get copd since i never smoked?
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life.
    My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.

More questions for: Cyclobenzaprine Hydrochloride, Seroquel

You may be interested at these reviews (Write a review):

  • Terrible excessive sweating from hydrochlorothiazide
    I guess I fit the profile of who gets excessive sweating from HCTZ. I am a 65 year old female and suffered from excessive sweating for two years. With just very little exertion, I would pour sweat from the top of my head. It would run into my face and all over my hair. My hair would be ringing wet. I had heavy perspiration in the groin area and down my back also. I had to change clothing 2-3 times a day and wash up or shower that many times also. The doctor tried changing my Cymbalta and put me on Wellbutrin instead. It did absolutely no good. I went off the wellbutrin and back onto the Cymbalta. I did some research and saw that HCTZ could cause excessive sweating. Both my doctor and my pharmacist said that they had never heard of that. I went off the HCTZ, and my sweating stopped almost immediately. My doctor and my pharmacist were very surprised. I'm one of those people who frequently have different reactions to drugs than are typical. If you're having excessive perspiration and are on HCTZ, try going off of it. It just may be the culprit!
  • Bipolar patient extremely violent on seraquel
    I have been diagnosed bipolar for over 10 years. 3 years ago I was taken off of topamax and my seraquel was upped to 300 mg from 100 because I was pregnant. I was very violent! Punching, breaking stuff, in jail, in the psych ward. Yes pregnancy and bipolar are not a perfect combination. I too thought it was the hormones. My husband and split several times over me punching him. We moved to a state cross country so there was no more family drama. Nothing worked! Over the last 3 years my life has been hell! I happen to run out of my seroquel (tg) it took 2 weeks to arrive. In that time my body went thru horrible withdrawals. I vowed I wouldn't take it any longer. I've been seraquel free for 2 months. I'm now on gabapentin and proud to say I have no anger issues! Not 1 punch has
    been thrown. I feel like a totally different person.
  • Seroquel and iron deficiency?
    I've been taking Seroquel for about four year, I have been having symptoms similar to hypothyroidism, and just found out I have an iron deficiency. The doctor said my platelets are smaller than average, and it is possible that my grandmother is anemic. But in trying to study Seroquel I kept finding things that made me wonder if Seroquel could be linked to iron deficiency.
  • Transition from mirtazapine to cymbalta (bipolar ii) 6 week duration taken in conjunction with seroquel, propranalol and implanon
    In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started.

    My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have now been on 60mg of Cymbalta for about 4 weeks and completely titrated off the Mirtazapine.

    I have noted that since switching to Cymbalta that I no longer have the insatiable appetite, nor have I had any further sleep paralysis episodes (though I have had a brain MRI to rule out any physiological issues - yet to receive results).

    I have noticed that I have had mild to moderate rolling nausea with the Cymbalta and that I now have food aversions. Food does not interest me as much anymore and I find that certain foods (mostly processed snacks) are no longer palatable. I also find that I become full after much smaller meal portions.

    I have found that I can no longer drink wine or spirits because they now taste awful however I can still tolerate certain brands of beer. I also no longer enjoy drinking cola.

    I am also on the Implanon Implant. I have had this implant inserted for about 12 months and my cycles have been rather regular. Since starting the Cymbalta I have had some breakthrough bleeding yet my periods have not been as painful, though they have been heavier and longer.

    My Psychiatrist will commence titrating me off the Seroquel in about two weeks and onto Topamax as it is his belief it will be less sedating than the Seroquel and that it will hopefully help as a mood stabiliser, treat my migraines and allow me to come off the Propranolol. he also hopes that I am able to loose some of the weight gained since the sleep paralysis episodes started.

    As a side note regarding the Propranolol, I have naturally low blood pressure and I find while Propranalol is generally an effective migraine prophylactic, (I do get some breakthrough migraines) it does make my blood pressure even lower which leads to dizziness and faintness when I stand up too quickly from a recumbent position.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.

More reviews for: Cyclobenzaprine Hydrochloride, Seroquel

Comments from related studies:

  • From this study (1 month ago):

  • peanuts on Mar, 31, 2010:

    my friend is suffering from rhumatory arthertis.and is currenty taking cocaine. oxy cotin,prestine, wellbutrim, predisone 10mg what side effects should she expect ?????

    Reply

    mtntexas on May, 11, 2013:

    Just ask John Belushi

    Reply

    2cents on Mar, 6, 2013:

    I'll second that!

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Cyclobenzaprine Hydrochloride (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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