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Review: taking Soma and Xanax together

Summary: drug interactions are reported among people who take Soma and Xanax together.

This review analyzes the effectiveness and drug interactions between Soma and Xanax. It is created by eHealthMe based on reports of 2,107 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 5, 2015: 2,106 people who take Soma, Xanax are studied

Soma, Xanax outcomes

Drug combinations in study:
- Soma (carisoprodol)
- Xanax (alprazolam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Soma is effective11.76%
(2 of 17 people)
(7 of 19 people)
(7 of 14 people)
(5 of 15 people)
(8 of 27 people)
(8 of 13 people)
(2 of 7 people)
(3 of 5 people)
Xanax is effective40.00%
(4 of 10 people)
(5 of 12 people)
(10 of 17 people)
(5 of 15 people)
(14 of 33 people)
(11 of 16 people)
(8 of 14 people)
(3 of 3 people)

Drug effectiveness by gender :

Soma is effective26.58%
(21 of 79 people)
(21 of 38 people)
Xanax is effective48.75%
(39 of 80 people)
(21 of 40 people)

Drug effectiveness by age :

Soma is effectiven/an/a100.00%
(1 of 1 people)
(5 of 16 people)
(13 of 44 people)
(13 of 72 people)
(9 of 38 people)
(1 of 11 people)
Xanax is effectiven/an/a0.00%
(0 of 1 people)
(7 of 15 people)
(18 of 47 people)
(20 of 74 people)
(12 of 38 people)
(3 of 12 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Suicide AttemptBack DisorderDrug Exposure During PregnancyHeart Valve IncompetenceRoad Traffic AccidentNauseaAggressionAnxiety
Drug ToxicityDepressionDevelopmental DelayDrug Exposure During PregnancyHeadacheDrug Withdrawal SyndromeAnxietyDepression
AnxietyPanic AttackDry MouthLoss Of ConsciousnessHallucinationDysarthriaAbnormal BehaviourNausea
Multi-organ FailureRoad Traffic AccidentGlossodyniaObstructive Airways DisorderDepressionHeadacheVascular InsufficiencyPain
Oedema PeripheralAnxietyPhotophobiaBundle Branch Block RightTremorTremorSudden Cardiac DeathInsomnia
Groin PainMyocardial InfarctionLoss Of AppetitePulmonary Valve StenosisDisorientationDrug DependenceDepressionHeadache
FearLoss Of AppetiteFear, FocusVentricular Septal DefectConfusional StateHypoaesthesiaEmotional DistressBack Pain
Deep Vein ThrombosisHypokalaemiaInsomniaHepatic SteatosisConstipationFibula FractureDeep Vein ThrombosisDrug Ineffective
Anoxic EncephalopathyConvulsionDental PlaqueHypertensionFatigueFoot FracturePulmonary EmbolismDrug Withdrawal Syndrome
Brain DeathVomitingConstipationHemiparesisNauseaFatigueSuicide AttemptDrug Dependence

Most common drug interactions by gender * :

NauseaDrug Dependence
DepressionDrug Withdrawal Syndrome
Back PainInsomnia
FallDrug Ineffective
Pain In ExtremityHypoaesthesia
FatigueBack Pain

Most common drug interactions by age * :

n/an/aDrug AbuserNauseaNauseaDepressionDepressionAnxiety
Completed SuicideInsomniaDepressionAnxietyNauseaPain
Cardiac ArrestDrug Withdrawal SyndromeAnxietyNauseaInsomniaFall
Respiratory ArrestDrug DependenceDrug Withdrawal SyndromeDrug Withdrawal SyndromeAnxietyBack Pain
AggressionDrug AbuserBack PainDrug DependencePainPain In Extremity
ConvulsionPainInsomniaDrug IneffectiveFallNausea
Multiple Drug OverdoseSuicidal IdeationArthralgiaHeadacheHeadacheOsteoarthritis
Nasal CongestionCompleted SuicideHypoaesthesiaInsomniaGait DisturbanceWeight Decreased
Drug Screen PositiveAnxietyFatigueFatigueBack PainHeadache
NauseaDrug IneffectiveHeadachePainChest PainDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Soma (carisoprodol) is often used to treat muscle spasms. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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