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Review: Spiriva and Chantix

This review analyzes the effectiveness and drug interactions between Spiriva and Chantix. It is created by eHealthMe based on reports of 1,570 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Spiriva and Chantix >>>

What are the drugs

Spiriva (latest outcomes from 50,453 users) has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease.

Chantix (latest outcomes from 64,412 users) has active ingredients of varenicline tartrate. It is often used in quit smoking.

On Sep, 14, 2014: 1,570 people who take Spiriva, Chantix are studied

Spiriva, Chantix outcomes

Drug combinations in study:
- Spiriva (tiotropium bromide monohydrate)
- Chantix (varenicline tartrate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Spiriva is effective0.00%
(0 of 2 people)
(1 of 2 people)
(1 of 2 people)
(1 of 3 people)
(1 of 1 people)
(1 of 1 people)
Chantix is effective66.67%
(2 of 3 people)
(4 of 5 people)
(2 of 2 people)
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDepressionDepressionDepressionDepressionCardiac Disordern/aNausea
DyspnoeaAnxietyAbnormal DreamsAnxietyAnxietyAbnormal DreamsDyspnoea
VomitingNauseaAnxietyDrug IneffectiveSuicide AttemptRenal FailureAnxiety
Abnormal DreamsSuicidal IdeationAggressionNightmareAggressionVomiting
Feeling AbnormalInsomniaChronic Obstructive Pulmonary DiseaseInsomniaBipolar DisorderDepression
Drug IneffectiveDyspnoeaDysgeusiaDyspnoeaIntentional OverdosePain
MalaiseAbnormal BehaviourNauseaAbnormal DreamsSuicidal IdeationChronic Obstructive Pulmonary Disease
InsomniaDrug IneffectiveDyspnoeaSuicide AttemptInsomniaInsomnia
DizzinessAggressionWeight IncreasedChronic Obstructive Pulmonary DiseaseFallMalaise
Chest PainWeight IncreasedAbnormal BehaviourMood SwingsMajor DepressionWeight Increased

Drug effectiveness by gender :

Spiriva is effective62.50%
(5 of 8 people)
(0 of 3 people)
Chantix is effective87.50%
(7 of 8 people)
(2 of 4 people)

Most common drug interactions by gender * :

VomitingChronic Obstructive Pulmonary Disease
Weight IncreasedDepression
Abnormal DreamsAsthenia
InsomniaBack Pain

Drug effectiveness by age :

Spiriva is effectiven/an/an/a0.00%
(0 of 1 people)
(1 of 1 people)
(3 of 12 people)
(1 of 5 people)
Chantix is effectiven/an/an/a0.00%
(0 of 1 people)
(1 of 1 people)
(4 of 12 people)
(4 of 6 people)

Most common drug interactions by age * :

n/an/an/aPharyngeal OedemaAnxietyNauseaNauseaNausea
DysphagiaWeight IncreasedAnxietyDyspnoeaDyspnoea
Swollen TongueSuicidal IdeationVomitingDrug IneffectiveAnxiety
FatigueDepressionVomitingChronic Obstructive Pulmonary Disease
DyspnoeaOedema PeripheralAbnormal DreamsPain
MalaiseChest PainNervousnessInsomnia
ParaesthesiaSuicidal IdeationMalaiseBronchitis
ArthralgiaHypertensionStressAbnormal Dreams

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Spiriva and Chantix?

Get connected! Join a mobile support group:
- group for people who take Spiriva and Chantix
- group for people who take Chantix
- group for people who take Spiriva

Comments from related studies:

  • From this study (2 years ago):

  • Dry itchy eyes, blurred vision, tight chest, fatigue, bothered by bright sun


  • From this study (2 years ago):

  • Just started tonight. Relatively dense. Trunk only


  • From this study (4 years ago):

  • In spite of not eating green foods or taking NSAIDS, my INR is either way low or way high (1.3-6.1) I cannot seem to get this stabalized and have had increasing clotting in my left leg as a result. Could it be the tramadol? If so, what else could I take for fairly severe pain from arthritis and fibromyalgia? Thanks.


Can you answer these questions (what is this?):

More questions for: Chantix, Spiriva

You may be interested at these reviews (what is this?):

  • Side effect of spiriva on diabetis control
    I have been a diabetic for the past 30 years and could generally control my blood sugar by using Lantus and another fast effect insuine (ahich changed several time)Since I take Spiriva (started on february 15th 2014, I cannot control my blood sugar properly and get incoherent results (2,3 or even 4 ...

  • Cfs/fibro, migraine
    A strange thing happened when I started taking the Chantix for my smoking cessation... MY MIGRAINES AND TENSION HEADACHES WENT AWAY!!! As horrible as they were, and as bad as I have prayed for them to go away, I did not even notice that I didn't have the excruciating headaches anymore!! I stop ...

  • Really works to quit smoking
    Works great for quitting smoking! The first few weeks you dream in technicolor just like an anti depressant but then that goes away. The only side effect I had was constipation but it was a small price to pay for quitting after 37 years a smoker! I tried hypnotism, patches, etc. but this really work ...

More reviews for: Chantix, Spiriva

Complete drug side effects:

On eHealthMe, Spiriva (tiotropium bromide monohydrate) is often used to treat chronic obstructive pulmonary disease. Chantix (varenicline tartrate) is often used to treat quit smoking. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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