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Home > Spironolactone > Benadryl > Spironolactone and Benadryl

Review: Spironolactone and Benadryl

Summary: drug interactions are reported among people who take Spironolactone and Benadryl together.

This review analyzes the effectiveness and drug interactions between Spironolactone and Benadryl. It is created by eHealthMe based on reports of 572 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Spironolactone and Benadryl >>>

What are the drugs

Spironolactone (latest outcomes from 26,420 users) has active ingredients of spironolactone. It is often used in acne.

Trend of spironolactone reports

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Trend of benadryl reports

On Nov, 27, 2014: 572 people who take Spironolactone, Benadryl are studied

Spironolactone, Benadryl outcomes

Drug combinations in study:
- Spironolactone (spironolactone)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Spironolactone is effective0.00%
(0 of 1 people)
n/an/a60.00%
(3 of 5 people)
33.33%
(1 of 3 people)
50.00%
(1 of 2 people)
n/an/a
Benadryl is effective50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
0.00%
(0 of 3 people)
n/a75.00%
(3 of 4 people)
33.33%
(1 of 3 people)
n/a100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Orthostatic HypotensionArthralgiaNauseaBipolar Ii DisorderSeromaErectile Dysfunctionn/aNausea
HyponatraemiaCryingLoss Of AppetiteHypomaniaSleep Disorder Due To General Medical Condition, Insomnia TypeDyspnoea
HypersensitivityDepressionLack Of Strength, Muscle Weakness, WeaknessGender Identity DisorderPain
LethargyCardiomyopathyOrgasmic DysfunctionOrgasmic Sensation DecreasedFatigue
AstheniaCardiac Failure CongestiveOrgasmic Sensation DecreasedOrgasmic DysfunctionCardiac Failure Congestive
DiarrhoeaAngerApathyLoss Of AppetiteVomiting
Dermatitis AcneiformAnxietySuicide AttemptLack Of Strength, Muscle Weakness, WeaknessAnxiety
SyncopeInsomniaAstheniaBreathing - Slowed Or StoppedPneumonia
JaundiceSleep Apnoea SyndromeAnorgasmiaTachycardiaOedema Peripheral
PyrexiaMyocardial InfarctionLoss Of LibidoPanic AttacksAsthenia

Drug effectiveness by gender :

FemaleMale
Spironolactone is effective50.00%
(4 of 8 people)
33.33%
(1 of 3 people)
Benadryl is effective45.45%
(5 of 11 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
NauseaDyspnoea
PainCardiac Failure Congestive
AnxietyNausea
AstheniaHypotension
FatiguePneumonia
VomitingFatigue
DyspnoeaVomiting
Oedema PeripheralOedema Peripheral
Urinary Tract InfectionBack Pain
DiarrhoeaCholelithiasis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Spironolactone is effectiven/an/an/a2.86%
(1 of 35 people)
100.00%
(1 of 1 people)
33.33%
(2 of 6 people)
0.00%
(0 of 2 people)
50.00%
(1 of 2 people)
Benadryl is effectiven/an/an/a5.71%
(2 of 35 people)
14.29%
(2 of 14 people)
8.33%
(1 of 12 people)
50.00%
(1 of 2 people)
0.00%
(0 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
TachycardiaTracheobronchitisDyspnoea ExertionalInsomniaNauseaAnxietyCardiac Failure CongestiveAsthenia
WheezingGastroenteritis ViralFatigueUrinary Tract InfectionChest PainPainDyspnoeaNausea
PyrexiaPseudomonal BacteraemiaNauseaNauseaCholelithiasisBack PainPainHypotension
Cardio-respiratory ArrestFallAbdominal DistensionPericardial EffusionDiarrhoeaDepressionHepatic FailureFatigue
Respiratory DistressUpper Limb FracturePalpitationsInfluenza Like IllnessHypertensionOedema PeripheralAnxietyAnaemia
VomitingStaphylococcal InfectionChest Pain AggravatedBronchitisGallbladder DisorderDyspnoeaCholelithiasisVomiting
InfectionCentral Line InfectionCardiac ArrestCholecystitisAbdominal Pain UpperArthralgiaCoughDyspnoea
DiarrhoeaRetchingDizzinessCardiac Failure CongestiveBlood Bilirubin IncreasedEar PainDeep Vein ThrombosisCardiac Failure Congestive
CyanosisHeart Rate IncreasedImplant Site InfectionCerebral IschaemiaInjuryCardiac Failure CongestiveAzotaemiaThrombocytopenia
ConvulsionTremorPulmonary HaemorrhageSinusitisHeadacheAspartate Aminotransferase IncreasedNauseaDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Spironolactone and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Spironolactone and Benadryl
- support group for people who take Benadryl
- support group for people who take Spironolactone

Can you answer these questions (Ask a question):

More questions for: Benadryl, Spironolactone

You may be interested at these reviews (Write a review):

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    (Posted by a 54 year old man who has Nightmare, Hard Time Sleeping, and takes Benadryl)
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I ...

  • Benadryl completed suicide 50 year old
    (Posted by a 50 year old woman who has Completed Suicide, and takes Alcohol, Methenamine Hippurate, Xanax, Benadryl)
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

  • Had nms in 2005, will trileptal increase chance of recurrence?
    (Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

  • Abnormal orgasm after likely caused by taking spironolactone
    (Posted by a 51 year old woman who has Hair Loss In Women, and takes Spironolactone)
    I was taking Spironolactone to assist with hairloss for approx 7 years. Although the drug did help to stop hair falling out it also caused abnormal orgasm and after 12 months of not taking the drug I am still unable to climax normally. My doctor cannot give me a full explanation for this.

  • Ovary pain disappeared
    (Posted by a 43 year old woman who has Ovarian Cyst, and takes Spironolactone)
    I have been taking Spironolactone 50mg for over a year that was prescribed by my dermatologist for acne. Prior to this I had daily pain in my right ovary for the previous 2 years with laproscopic surgery for tubal ligation the gyn did not see anything on this ovary to cause the pain, but my pain is ...

More reviews for: Benadryl, Spironolactone

Complete drug side effects:

On eHealthMe, Spironolactone (spironolactone) is often used to treat acne. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Benadryl, Spironolactone

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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