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Review: Spironolactone and Omeprazole

This review analyzes the effectiveness and drug interactions between Spironolactone and Omeprazole. It is created by eHealthMe based on reports of 4,445 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Spironolactone and Omeprazole >>>

What are the drugs

Spironolactone (latest outcomes from 26,372 users) has active ingredients of spironolactone. It is often used in acne.

Omeprazole (latest outcomes from 92,596 users) has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease.

On Jul, 13, 2014: 4,445 people who take Spironolactone, Omeprazole are studied

Spironolactone, Omeprazole outcomes

Drug combinations in study:
- Spironolactone (spironolactone)
- Omeprazole (omeprazole)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Spironolactone is effective0.00%
(0 of 3 people)
55.56%
(5 of 9 people)
12.50%
(1 of 8 people)
42.86%
(3 of 7 people)
50.00%
(5 of 10 people)
50.00%
(4 of 8 people)
80.00%
(4 of 5 people)
n/a
Omeprazole is effective66.67%
(2 of 3 people)
85.71%
(6 of 7 people)
50.00%
(1 of 2 people)
50.00%
(4 of 8 people)
71.43%
(10 of 14 people)
63.64%
(7 of 11 people)
50.00%
(2 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug Rash With Eosinophilia And Systemic SymptomsRenal Failure AcuteRenal Failure AcuteRenal Failure AcuteHyperkalaemiaHypomagnesaemiaNephrotic SyndromeNausea
Hepatic EncephalopathyDehydrationFatigueHyperkalaemiaRenal Failure AcuteHypokalaemiaHyperkalaemiaDyspnoea
HyperkalaemiaHyperkalaemiaHyperkalaemiaHyponatraemiaHepatic EncephalopathyHypocalcaemiaFallVomiting
Renal Failure AcuteVomitingTubulointerstitial NephritisPulmonary EmbolismRenal ImpairmentHallucinationRenal FailureRenal Failure Acute
MalaiseDyspnoeaMyalgiaDyspnoeaPulmonary EmbolismAgitationBlood Calcium DecreasedDehydration
DyspnoeaPancytopeniaHypokalaemiaAcidosisRight Ventricular FailureMuscle DisorderBundle Branch Block RightFall
PyrexiaNauseaImpaired HealingNauseaAtrioventricular Block CompleteHypophosphataemiaAtrial FibrillationAtrial Fibrillation
PneumoniaAscitesInfluenza Like IllnessMalaiseCondition AggravatedDiarrhoeaFemoral Neck FracturePain
Atrial FibrillationStevens-johnson SyndromeToothacheCholecystitis ChronicPulmonary HypertensionVomitingDeathFatigue
Blood Urea IncreasedDecreased AppetiteHypersomniaAnxietyBlood Creatinine IncreasedCondition AggravatedSupraventricular ExtrasystolesCardiac Failure Congestive

Drug effectiveness by gender :

FemaleMale
Spironolactone is effective45.95%
(17 of 37 people)
38.46%
(5 of 13 people)
Omeprazole is effective64.86%
(24 of 37 people)
66.67%
(8 of 12 people)

Most common drug interactions by gender * :

FemaleMale
NauseaDyspnoea
Renal Failure AcuteNausea
DyspnoeaVomiting
DehydrationHypotension
VomitingRenal Failure Acute
PainAscites
FallCardiac Failure Congestive
AnxietyPneumonia
Oedema PeripheralAtrial Fibrillation
AstheniaFatigue

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Spironolactone is effectiven/an/an/a37.50%
(3 of 8 people)
9.09%
(1 of 11 people)
38.46%
(5 of 13 people)
33.33%
(4 of 12 people)
22.50%
(9 of 40 people)
Omeprazole is effectiven/an/an/a42.86%
(3 of 7 people)
36.36%
(4 of 11 people)
53.85%
(7 of 13 people)
30.77%
(4 of 13 people)
35.90%
(14 of 39 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Chronic Obstructive Pulmonary DiseaseCryingDrug Rash With Eosinophilia And Systemic SymptomsAbdominal PainNauseaNauseaNauseaNausea
Acquired MethaemoglobinaemiaNightmarePyrexiaWeight DecreasedPyrexiaDehydrationDyspnoeaRenal Failure Acute
Mean Arterial Pressure DecreasedScreamingAscitesAnxietyMalaiseBack PainVomitingDyspnoea
Heart Rate DecreasedPancytopeniaHeart Rate DecreasedHaematocheziaCholecystitis ChronicPyrexiaAscitesFall
Electrocardiogram St Segment ElevationDiarrhoeaHistiocytosis HaematophagicGastrooesophageal Reflux DiseasePainWeight IncreasedDiarrhoeaAtrial Fibrillation
Central Venous Pressure IncreasedAbdominal PainMalaiseFlight Of IdeasVomitingGastrooesophageal Reflux DiseaseAbdominal PainVomiting
Pulse Pressure DecreasedCholecystitis AcuteHepatomegalyCrohn's DiseaseUrinary Tract InfectionHypertensionPyrexiaHypotension
Pupil FixedHypertensionDepressed Level Of ConsciousnessColitisAscitesRenal Failure AcuteAnaemiaCardiac Failure Congestive
PyrexiaCardiac FailureComputerised Tomogram AbnormalDepressionAnxietyOedemaAstheniaPain
Ventricular FibrillationPeritonitisAtelectasisInflammatory Bowel DiseaseAbdominal PainAtrial FibrillationFatigueAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Spironolactone and Omeprazole
- group for people who take Omeprazole
- group for people who take Spironolactone

Comments from related studies:

  • From this study (11 hours ago):

  • I have severe nausea, dizziness,headache, incontinence when taking Fondapariaux Sodium and Aritra have light headness, somnolence. I need to be on a anticoagulant because of stents just placed 6 months ago.

    Reply

  • From this study (8 months ago):

  • Flushing started Feb. 2013 with large hives. Face and neck become inflamed with burning pain, not itching. Had been on Celebrex several years ( also tried other NSAIDS including Ibuprofen, mobic and aspirin) For neck and joint pain as well as chronic plantar facitits. Episode seem less often without NSAIDS. Continue to have episodes regardless sometimes daily Although have had periods of no episodes for a week. Areas now have has permanent markings (scaring?)
    I have seen two dermatologist, family doctor, and allergist who cannot diagnose. Many lab test were within normal limits except mast cells were slightly elevated around 300. Aldactone is new Replacing HCTZ; Zantac, Allegra , and Zyrtec are new to help symptoms. Nasonex is also new . Tried topical steroid cream which was not effective. Thanks!

    Reply

  • From this study (1 year ago):

  • Would like to know how these drugs interact with each other. Also I have serious problem with dry eyes. Is that caused by one of these drugs. Do any of these drugs have serious side affects that I should be concerned about? My doctor recently added the Spironolactone but I have some reservations about taking it...is it safe?

    Reply

    eHealthMe support on Feb, 15, 2013:

    Hi,

    You need to enter dry eye or whatever adverse outcome to check in the drug checker, in order to get what you want

    Reply

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Complete drug side effects:

On eHealthMe, Spironolactone (spironolactone) is often used to treat acne. Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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