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Review: Sulfamethoxazole and Naproxen

This review analyzes the effectiveness and drug interactions between Sulfamethoxazole and Naproxen. It is created by eHealthMe based on reports of 71 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Sulfamethoxazole (what 2,423 Sulfamethoxazole users reported?) has active ingredients of sulfamethoxazole. It is used in urinary tract infection.

Naproxen (what 21,898 Naproxen users reported?) has active ingredients of naproxen. It is used in pain.

On Aug, 28, 2014: 71 people who take Sulfamethoxazole, Naproxen are studied

Sulfamethoxazole, Naproxen outcomes

Drug combinations in study:
- Sulfamethoxazole (sulfamethoxazole)
- Naproxen (naproxen)

Drug effectiveness over time :


Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Deep Vein ThrombosisPyrexian/an/aHypovolaemian/an/aFatigue
Pelvic Venous ThrombosisNauseaHeart PalpitationsAnaemia
Renal FailurePneumocystis Jiroveci PneumoniaCyanosisNausea
Venous OcclusionObstructive Airways DisorderRaynaud's PhenomenonAnxiety
AgranulocytosisDeep Vein ThrombosisDyspnoea
HypovolaemiaPain In ExtremityUrinary Tract Infection
CyanosisPulmonary InfarctionInjury
Heart PalpitationsPulmonary EmbolismPain
Raynaud's PhenomenonDyspnoeaEar Pain
Oedema PeripheralHypertension

Drug effectiveness by gender :


Most common drug interactions by gender * :

FatigueChronic Obstructive Pulmonary Disease
Urinary Tract InfectionBenign Prostatic Hyperplasia
InjuryIntervertebral Disc Protrusion
Ear PainOsteoarthritis
ArthralgiaBalance Disorder

Drug effectiveness by age :


Most common drug interactions by age * :

n/an/aCalculus UrinaryDeep Vein ThrombosisDiabetes MellitusFatiguePyrexiaNausea
Hepatic Function AbnormalRenal FailureDiabetes Mellitus Inadequate ControlUrinary Tract InfectionHypertensionAnaemia
GastroenteritisPelvic Venous ThrombosisDiabetic GastroparesisEar PainHyperlipidaemiaCerebrovascular Accident
PregnancyVenous OcclusionType 1 Diabetes MellitusArthralgiaIntervertebral Disc ProtrusionMuscle Spasms
NephrolithiasisMigrainePulmonary EmbolismMyalgiaLip SwellingGastric Ulcer
Abdominal Pain LowerRash Maculo-papularPulmonary InfarctionInjuryLung InfiltrationRenal Failure Chronic
VomitingOverdoseDeep Vein ThrombosisPruritusHepatic CystFatigue
Abortion SpontaneousType 2 Diabetes MellitusAnxietyDysgeusiaHallucination, VisualWeight Decreased
NauseaLiver TransplantEmotional DistressLeukocytosisDiverticulumTremor
Pancreatitis AcuteGeneral Physical Health DeteriorationAnaemiaDiarrhoeaHypertension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Sulfamethoxazole and Naproxen?

Get connected! Join a mobile support group:
- group for people who take Sulfamethoxazole and Naproxen
- group for people who take Naproxen
- group for people who take Sulfamethoxazole

Comments from related studies:

  • From this study (2 years ago):

  • I have had hypovolemia for seven years with internal bleeding. I suffered a bout of septicemia in 1997 that was not treated.


  • From this study (2 years ago):

  • I also suffered septicemia in 1997 (untreated) and the hypovolemia has been a problem since late-2005. I have had internal bleeding , with a rib jabbing the abdominal aortic artery occasional.


Can you answer these questions (what is this?):

More questions for: Naproxen, Sulfamethoxazole

You may be interested at these reviews (what is this?):

  • Eczema and birth control-microgestin
    I started getting eczema over the last year and recently decided it may be from the birth control as well, which I started taking @ 2 months before I got the eczema and skin started breaking out...weight gain, etc. I am on singulair, westcort cream, moisture/kenalog, exederm cream, cerevue wash, cet ...

  • Horrific nightmares taking naproxen
    I've Taking naproxen 500mg twice a day for 3 weeks on a course for 6 months, I've been having horrific dreams worse than horrer movies, the most recent is involving my ex & current partner where I had a psychotic stalker (my ex) switched around because in the dream I dump my partner for my ex, well ...

More reviews for: Naproxen, Sulfamethoxazole

Complete drug side effects:

On eHealthMe, Sulfamethoxazole (sulfamethoxazole) is often used to treat urinary tract infection. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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