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Review: taking Sulfamethoxazole and Naproxen together

Summary: drug interactions are reported among people who take Sulfamethoxazole and Naproxen together.

This review analyzes the effectiveness and drug interactions between Sulfamethoxazole and Naproxen. It is created by eHealthMe based on reports of 71 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Sulfamethoxazole and Naproxen >>>

On Apr, 1, 2015: 71 people who take Sulfamethoxazole, Naproxen are studied

Sulfamethoxazole, Naproxen outcomes

Drug combinations in study:
- Sulfamethoxazole (sulfamethoxazole)
- Naproxen (naproxen)

Drug effectiveness over time :


Drug effectiveness by gender :


Drug effectiveness by age :


Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Deep Vein ThrombosisPyrexian/an/aHypovolaemian/an/aFatigue
Pelvic Venous ThrombosisNauseaHeart PalpitationsAnaemia
Renal FailurePneumocystis Jiroveci PneumoniaCyanosisNausea
Venous OcclusionObstructive Airways DisorderRaynaud's PhenomenonAnxiety
AgranulocytosisDeep Vein ThrombosisDyspnoea
HypovolaemiaPain In ExtremityUrinary Tract Infection
CyanosisPulmonary InfarctionInjury
Heart PalpitationsPulmonary EmbolismPain
Raynaud's PhenomenonDyspnoeaEar Pain
Oedema PeripheralHypertension

Most common drug interactions by gender * :

FatigueChronic Obstructive Pulmonary Disease
Urinary Tract InfectionBenign Prostatic Hyperplasia
InjuryIntervertebral Disc Protrusion
Ear PainOsteoarthritis
ArthralgiaBalance Disorder

Most common drug interactions by age * :

n/an/aCalculus UrinaryDeep Vein ThrombosisDiabetes MellitusFatiguePyrexiaNausea
Hepatic Function AbnormalRenal FailureDiabetes Mellitus Inadequate ControlUrinary Tract InfectionHypertensionAnaemia
GastroenteritisPelvic Venous ThrombosisDiabetic GastroparesisEar PainHyperlipidaemiaCerebrovascular Accident
PregnancyVenous OcclusionType 1 Diabetes MellitusArthralgiaIntervertebral Disc ProtrusionMuscle Spasms
NephrolithiasisMigrainePulmonary EmbolismMyalgiaLip SwellingGastric Ulcer
Abdominal Pain LowerRash Maculo-papularPulmonary InfarctionInjuryLung InfiltrationRenal Failure Chronic
VomitingOverdoseDeep Vein ThrombosisPruritusHepatic CystFatigue
Abortion SpontaneousType 2 Diabetes MellitusAnxietyDysgeusiaHallucination, VisualWeight Decreased
NauseaLiver TransplantEmotional DistressLeukocytosisDiverticulumTremor
Pancreatitis AcuteGeneral Physical Health DeteriorationAnaemiaDiarrhoeaHypertension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Sulfamethoxazole and Naproxen?




You are not alone! Join a related support group:
- support group for people who take Naproxen
- support group for people who take Sulfamethoxazole

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Sulfamethoxazole (sulfamethoxazole) is often used to treat urinary tract infection. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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