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Review: taking Synthroid and Melatonin together

Summary: drug interactions are reported among people who take Synthroid and Melatonin together.

This review analyzes the effectiveness and drug interactions between Synthroid and Melatonin. It is created by eHealthMe based on reports of 467 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Synthroid and Melatonin >>>

What are the drugs

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from 93,791 Synthroid users)

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from 2,673 Melatonin users)

On Jan, 12, 2015: 448 people who take Synthroid, Melatonin are studied

Synthroid, Melatonin outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Melatonin (melatonin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effectiven/an/a50.00%
(2 of 4 people)
14.29%
(1 of 7 people)
50.00%
(5 of 10 people)
55.56%
(5 of 9 people)
73.68%
(14 of 19 people)
n/a
Melatonin is effective0.00%
(0 of 4 people)
27.27%
(3 of 11 people)
0.00%
(0 of 2 people)
37.50%
(3 of 8 people)
50.00%
(6 of 12 people)
20.00%
(1 of 5 people)
33.33%
(1 of 3 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PruritusAntepartum HaemorrhageCoughHeadache NosGallbladder DisorderHypersomnia - IdiopathicInsomniaNausea
Antepartum HaemorrhageIrritabilityBrain NeoplasmTeeth Grinding And ClenchingOsteonecrosisSkin Blushing/flushingDepressionHeadache
NasopharyngitisGastrointestinal DiscomfortMouth UlcerationMovement - UncoordinatedRashFibromyalgiaExercise Tolerance DecreasedFatigue
Rash Maculo-papularTremorMuscle TwitchingVision BlurredOrgan FailureArthritisDrug IneffectiveDrug Ineffective
EffusionDizzinessDystoniaDark Circles Under EyesCholecystitisAnemiaFatiguePain
DysphagiaDeja VuRashSupraventricular TachycardiaDeja VuSpondylolisthesisArthropathyInsomnia
Subchorionic HaemorrhageMouth UlcerationInsomnia Related To Another Mental ConditionGallbladder CholesterolosisAlopeciaFeeling AbnormalFall
Vitamin D DeficiencyVaginal SloughingNightmares - RepeatedDystoniaAnxietyGastrooesophageal Reflux DiseaseDizziness
Fungal InfectionDiarrhoeaUrethral PainMuscle TwitchingUrinary IncontinenceMood SwingsMalaise
HypertensionHypersomniaHigh Blood PressureUrethral PainStomach UpsetWeight IncreasedConvulsion

Drug effectiveness by gender :

FemaleMale
Synthroid is effective57.78%
(26 of 45 people)
25.00%
(1 of 4 people)
Melatonin is effective30.95%
(13 of 42 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
NauseaMyelodysplastic Syndrome
HeadacheRespiratory Failure
FatigueAnal Fistula
PainMetastases To Bone
InsomniaCrohn's Disease
Drug IneffectiveDrug Ineffective
MalaiseThyroid Cancer
AnxietyBlood Creatinine Increased
ConvulsionCellulitis
DizzinessHepatic Lesion

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Synthroid is effectiven/an/a0.00%
(0 of 1 people)
15.79%
(3 of 19 people)
22.22%
(2 of 9 people)
50.00%
(5 of 10 people)
30.43%
(7 of 23 people)
33.33%
(10 of 30 people)
Melatonin is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 19 people)
0.00%
(0 of 9 people)
25.00%
(2 of 8 people)
26.09%
(6 of 23 people)
17.86%
(5 of 28 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Respiratory DistressSkin HypertrophyAnal FistulaMuscle SpasmsHeadachePruritusDrug IneffectiveNausea
VasculitisCrohn's DiseaseHypothyroidismConvulsionAnxietyInsomniaFatigue
Abdominal PainHeadacheLymphopeniaEpilepsyFatigueDyspnoeaFall
Pulmonary OedemaHaemorrhagic Cerebral InfarctionHyponatraemiaInjuryWeight IncreasedHeadacheAnxiety
Radiation InjuryConfusional StateHeadacheUrinary Tract InfectionNasopharyngitisFatigueConfusional State
Arterial Occlusive DiseaseSpastic DiplegiaDiplopiaPainDiarrhoeaGastrooesophageal Reflux DiseasePain
DehydrationPneumonia AspirationNeutropeniaDecreased AppetiteDyspepsiaRashHeadache
Cerebrovascular AccidentTransverse Sinus ThrombosisHypocalcaemiaBalance DisorderDry MouthParaesthesiaDiarrhoea
DiarrhoeaConvulsionPyrexiaFluid RetentionSoft Tissue NecrosisNauseaDepression
ScreamingPerirectal AbscessDiabetes MellitusDizzinessWound ComplicationBlood Creatinine IncreasedDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and Melatonin?

You are not alone! Join a related mobile support group:
- support group for people who take Synthroid and Melatonin
- support group for people who take Melatonin
- support group for people who take Synthroid

Can you answer these questions (Ask a question):

More questions for: Melatonin, Synthroid

You may be interested at these reviews (Write a review):

  • Syntroid and pruritus
    I have been on levothyroxine for more than ten years and have had two episodes, each lasting over several months of unbearable itching. Doctors seem to deny any connection but are also unable identify the cause of the itching. None of the tests pick anything. Antihistamines are not much of a help. I am still in the throes of the second episode and life is plain, simple miserable.
  • Thrush while on prograf
    I am a health provider at an emergency room and had a patient come in because of a food bolus and when i examined his oral/pharynx I noticed he had thrush. Patient stated it has been their for a while. Patient also stated he has been having progressive difficulty in swallowing. Pt is a kidney transplant patient and has been worked up for other causes of his thrush (including HIV, as per patient results neg) and everything came back negative. I can only conclude that maybe the prograf which is a immunosupressent can possible be the cause
  • Cardio version caused fingernail abnormalities
    Right hip fracture. When prepping for surgery AFIB was found. Surgery was cancelled and they attempted to get AFIB under control. Finally, cardioversion was performed. When my nails started to grow out they all had two horizontal lines that cause the nail to break when it grows out to that point.
  • Synthroid and breast enlargement
    I have went from a B-C cup size to a D cup in the past 8-9 months.
  • Double vision on levothyroxine
    Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Levothyrixine and have increased as my dose has been increased.

More reviews for: Melatonin, Synthroid

Comments from related studies:

  • From this study (2 weeks ago):

  • Possible sjorens schitzoaffective bipolar type

    Reply

  • From this study (4 months ago):

  • Depression diagnosed first, and eventually identified as cyclothymia. Arthritis second. Hypothyroid and high cholesterol next. Headaches resolved with menopause, but have come back. Allergic reactions to unknown things about same time as headaches.

    Reply

  • From this study (7 months ago):

  • Alpha Liponic Acid....kidney failure < month
    Critical Liver Support...Kidney failure < month
    Charcoal Activated... Absorb impurities < month

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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