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Review: Synthroid and Melatonin

This review analyzes the effectiveness and drug interactions between Synthroid and Melatonin. It is created by eHealthMe based on reports of 465 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Synthroid and Melatonin >>>

What are the drugs

Synthroid (what 93,655 Synthroid users reported?) has active ingredients of levothyroxine sodium. It is used in hypothyroidism.

Melatonin (what 2,634 Melatonin users reported?) has active ingredients of melatonin. It is used in insomnia.

On Sep, 11, 2014: 446 people who take Synthroid, Melatonin are studied

Synthroid, Melatonin outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Melatonin (melatonin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effectiven/an/a50.00%
(2 of 4 people)
14.29%
(1 of 7 people)
50.00%
(5 of 10 people)
50.00%
(4 of 8 people)
77.78%
(14 of 18 people)
n/a
Melatonin is effective0.00%
(0 of 4 people)
27.27%
(3 of 11 people)
0.00%
(0 of 2 people)
37.50%
(3 of 8 people)
54.55%
(6 of 11 people)
20.00%
(1 of 5 people)
0.00%
(0 of 2 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PruritusAntepartum HaemorrhageCoughHeadache NosOrgan FailureHypersomnia - IdiopathicInsomniaNausea
Antepartum HaemorrhageIrritabilityBrain NeoplasmTeeth Grinding And ClenchingGallbladder DisorderAlopeciaExercise Tolerance DecreasedHeadache
NasopharyngitisGastrointestinal DiscomfortMouth UlcerationMovement - UncoordinatedOsteonecrosisFibromyalgiaFatigueFatigue
Rash Maculo-papularTremorMuscle TwitchingVision BlurredCholecystitisArthritisWeight IncreasedDrug Ineffective
EffusionDizzinessDystoniaDark Circles Under EyesGallbladder CholesterolosisAnemiaDrug IneffectivePain
DysphagiaDeja VuRashSupraventricular TachycardiaLoss Of HairSpondylolisthesisArthropathyInsomnia
Subchorionic HaemorrhageMouth UlcerationInsomnia Related To Another Mental ConditionDeja VuAnxietyGastrooesophageal Reflux DiseaseFall
Vitamin D DeficiencyVaginal SloughingNightmares - RepeatedRashFeeling AbnormalMood SwingsDizziness
Fungal InfectionDiarrhoeaUrethral PainDystoniaUrinary IncontinenceInflammationMalaise
HypertensionHypersomniaHigh Blood PressurePtsdStomach UpsetGluten IntoleranceConvulsion

Drug effectiveness by gender :

FemaleMale
Synthroid is effective58.14%
(25 of 43 people)
25.00%
(1 of 4 people)
Melatonin is effective30.00%
(12 of 40 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
NauseaMyelodysplastic Syndrome
HeadacheRespiratory Failure
FatigueAnal Fistula
PainMetastases To Bone
InsomniaCrohn's Disease
Drug IneffectiveDrug Ineffective
MalaiseThyroid Cancer
AnxietyBlood Creatinine Increased
ConvulsionCellulitis
FallHepatic Lesion

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Synthroid is effectiven/an/a0.00%
(0 of 1 people)
15.79%
(3 of 19 people)
22.22%
(2 of 9 people)
50.00%
(5 of 10 people)
30.43%
(7 of 23 people)
36.00%
(9 of 25 people)
Melatonin is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 19 people)
0.00%
(0 of 9 people)
25.00%
(2 of 8 people)
26.09%
(6 of 23 people)
17.39%
(4 of 23 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Respiratory DistressSkin HypertrophyAnal FistulaMuscle SpasmsHeadachePruritusDrug IneffectiveNausea
VasculitisCrohn's DiseaseHypothyroidismConvulsionAnxietyInsomniaFatigue
Abdominal PainHeadacheLymphopeniaEpilepsyFatigueDyspnoeaFall
Pulmonary OedemaHaemorrhagic Cerebral InfarctionHyponatraemiaInjuryWeight IncreasedHeadacheAnxiety
Radiation InjuryConfusional StateHeadacheUrinary Tract InfectionNasopharyngitisFatigueConfusional State
Arterial Occlusive DiseaseSpastic DiplegiaDiplopiaPainDiarrhoeaGastrooesophageal Reflux DiseasePain
DehydrationPneumonia AspirationNeutropeniaDecreased AppetiteDyspepsiaRashHeadache
Cerebrovascular AccidentTransverse Sinus ThrombosisHypocalcaemiaBalance DisorderDry MouthParaesthesiaDizziness
DiarrhoeaConvulsionPyrexiaFluid RetentionSoft Tissue NecrosisNauseaDiarrhoea
ScreamingPerirectal AbscessDiabetes MellitusDizzinessWound ComplicationBlood Creatinine IncreasedAbdominal Pain Upper

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Synthroid and Melatonin
- group for people who take Melatonin
- group for people who take Synthroid

Comments from related studies:

  • From this study (2 months ago):

  • Alpha Liponic Acid....kidney failure < month
    Critical Liver Support...Kidney failure < month
    Charcoal Activated... Absorb impurities < month

    Reply

  • From this study (6 months ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

  • From this study (9 months ago):

  • onset one month ago started after treatment of UTI

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Melatonin, Synthroid

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  • I need advise, badly ckd!!
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passe ...

  • Melatonin reduces essential tremor of the hand
    After taking Melatonin 1mg as a sleep aid for several nights, I noticed that my essential tremor of the hand was showing improvement. Within a week the tremor was almost unnoticeable, and I could print and write neatly, even when slightly stressed at work. I haven't seen this response reported any ...

  • Shortness of breath after taking levothyroxine for 8-10 yrs.
    I have been experiencing shortness of breath lately when taking the levothyroxine. If I stop taking it for a couple of days my shortness of breath is pretty much gone.

More reviews for: Melatonin, Synthroid

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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