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Review: taking Synthroid and Melatonin together

Summary: drug interactions are reported among people who take Synthroid and Melatonin together.

This review analyzes the effectiveness and drug interactions between Synthroid and Melatonin. It is created by eHealthMe based on reports of 470 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from 93,823 Synthroid users)

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from 2,682 Melatonin users)

On Feb, 12, 2015: 451 people who take Synthroid, Melatonin are studied

Synthroid, Melatonin outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Melatonin (melatonin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effectiven/a0.00%
(0 of 1 people)
50.00%
(2 of 4 people)
14.29%
(1 of 7 people)
45.45%
(5 of 11 people)
55.56%
(5 of 9 people)
70.00%
(14 of 20 people)
n/a
Melatonin is effective0.00%
(0 of 4 people)
27.27%
(3 of 11 people)
0.00%
(0 of 3 people)
33.33%
(3 of 9 people)
53.85%
(7 of 13 people)
20.00%
(1 of 5 people)
33.33%
(1 of 3 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PruritusAntepartum HaemorrhageHot FlashesVision BlurredGallbladder DisorderHypersomnia - IdiopathicInsomniaNausea
Antepartum HaemorrhageIrritabilityRheumatoid ArthritisMovement - UncoordinatedOsteonecrosisSkin Blushing/flushingDepressionHeadache
NasopharyngitisDizzinessBipolarHeadache NosRashFibromyalgiaArthropathyFatigue
Rash Maculo-papularTremorHigh Blood PressureSupraventricular TachycardiaOrgan FailureArthritisExercise Tolerance DecreasedDrug Ineffective
EffusionHypersomniaBrain NeoplasmDark Circles Under EyesCholecystitisAnemiaMood SwingsPain
DysphagiaGastrointestinal DiscomfortInsomniaLewy Body DementiaDiarrhoea AggravatedSpondylolisthesisDrug IneffectiveInsomnia
Subchorionic HaemorrhageMouth UlcerationDry MouthDiarrhoea AggravatedLewy Body DementiaAlopeciaGastrooesophageal Reflux DiseaseFall
Vitamin D DeficiencyDeja VuDry EyesTeeth Grinding And ClenchingGallbladder CholesterolosisAnxietyHigh Blood PressureDizziness
Fungal InfectionVaginal SloughingMuscle TwitchingInsomnia Related To Another Mental ConditionDystoniaUrinary IncontinenceAlopeciaMalaise
HypertensionDiarrhoeaDystoniaUrethral PainMuscle TwitchingStomach UpsetAnxietyConvulsion

Drug effectiveness by gender :

FemaleMale
Synthroid is effective55.32%
(26 of 47 people)
20.00%
(1 of 5 people)
Melatonin is effective31.82%
(14 of 44 people)
25.00%
(1 of 4 people)

Most common drug interactions by gender * :

FemaleMale
NauseaRespiratory Failure
HeadacheMyelodysplastic Syndrome
FatigueMetastases To Bone
InsomniaAnal Fistula
PainCrohn's Disease
Drug IneffectiveConfusional State
MalaiseThyroid Cancer
ConvulsionBlood Creatinine Increased
AnxietyCellulitis
DizzinessDizziness

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Synthroid is effectiven/an/a0.00%
(0 of 1 people)
15.79%
(3 of 19 people)
22.22%
(2 of 9 people)
50.00%
(5 of 10 people)
29.17%
(7 of 24 people)
24.39%
(10 of 41 people)
Melatonin is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 19 people)
0.00%
(0 of 9 people)
25.00%
(2 of 8 people)
29.17%
(7 of 24 people)
12.82%
(5 of 39 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Respiratory DistressSkin HypertrophyAnal FistulaMuscle SpasmsHeadachePruritusDrug IneffectiveNausea
VasculitisCrohn's DiseaseHypothyroidismConvulsionAnxietyInsomniaFatigue
Abdominal PainHeadacheLymphopeniaEpilepsyFatigueFatigueFall
Pulmonary OedemaHaemorrhagic Cerebral InfarctionHyponatraemiaInjuryWeight IncreasedHeadacheAnxiety
Radiation InjuryConfusional StateHeadacheUrinary Tract InfectionNasopharyngitisDyspnoeaConfusional State
Arterial Occlusive DiseaseSpastic DiplegiaDiplopiaPainDiarrhoeaGastrooesophageal Reflux DiseasePain
DehydrationPneumonia AspirationNeutropeniaDecreased AppetiteDyspepsiaRashInsomnia
Cerebrovascular AccidentTransverse Sinus ThrombosisHypocalcaemiaBalance DisorderDry MouthParaesthesiaDizziness
DiarrhoeaConvulsionPyrexiaFluid RetentionSoft Tissue NecrosisNauseaDiarrhoea
ScreamingPerirectal AbscessDiabetes MellitusDizzinessWound ComplicationMemory ImpairmentHeadache

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and Melatonin?

You are not alone! Join a related mobile support group:
- support group for people who take Synthroid and Melatonin
- support group for people who take Melatonin
- support group for people who take Synthroid

Can you answer these questions (Ask a question):

More questions for: Melatonin, Synthroid

You may be interested at these reviews (Write a review):

  • The dangers off fluoridation
    I live in an area where the water has been fluoridated for approximately 55 years and have been treated for an underactive thyroid since 1978. I have also suffered from urge incontinence since 1967 and for 4 years have also had the symptoms of skeletal fluorosis although I have not been able to get the tests to confirm this. About 2 years ago I read about the dangers of fluoride and stopped using the tap water for drinking and cooking but still had to use it for bathing and still swam in the local pool. Also I have always drunk about 3 pints of tea a day. Recently it was found that there might be a problem with my kidneys so I stopped drinking tea and swimming. I had been going to the toilet 16/17 times a day but after about 5 weeks this was down to 7/8 times and the urgency was gone. Also I was given a follow up kidney function test after 6 weeks and that was normal. A few weeks later I was shopping in an area where the water is not fluoridated and risked having tea in a cafe there and the irritable bladder symptoms came back almost immediately and lasted for several weeks.
  • Melatonin and diarrhrea
    A lifetime of wakefulness during the night, almost never more than 7 hrs sleep and awake 2-4 times a night. Return to sleep easily. Doctors gave sleep aids. Usually somewhat ineffective and sometimes groggy mornings. So I decided to go the more natural route ... melatonin. Worse. It did not work for me. It gave me some if the wateriest and longest lasting diarrhea of my life. The uncontrolled continuous diarrhea was worse than not sleeping at night. Not listed as one of the side affects of Melatonin. More people should be made aware of the dangers of this dehydration.
  • Syntroid and pruritus
    I have been on levothyroxine for more than ten years and have had two episodes, each lasting over several months of unbearable itching. Doctors seem to deny any connection but are also unable identify the cause of the itching. None of the tests pick anything. Antihistamines are not much of a help. I am still in the throes of the second episode and life is plain, simple miserable.
  • Thrush while on prograf
    I am a health provider at an emergency room and had a patient come in because of a food bolus and when i examined his oral/pharynx I noticed he had thrush. Patient stated it has been their for a while. Patient also stated he has been having progressive difficulty in swallowing. Pt is a kidney transplant patient and has been worked up for other causes of his thrush (including HIV, as per patient results neg) and everything came back negative. I can only conclude that maybe the prograf which is a immunosupressent can possible be the cause
  • Cardio version caused fingernail abnormalities
    Right hip fracture. When prepping for surgery AFIB was found. Surgery was cancelled and they attempted to get AFIB under control. Finally, cardioversion was performed. When my nails started to grow out they all had two horizontal lines that cause the nail to break when it grows out to that point.

More reviews for: Melatonin, Synthroid

Comments from related studies:

  • From this study (2 weeks ago):

  • Question whether diarrhea is caused by Medications or a symptom of Lew Body Dementia.

    Reply

  • From this study (1 month ago):

  • Possible sjorens schitzoaffective bipolar type

    Reply

  • From this study (5 months ago):

  • Depression diagnosed first, and eventually identified as cyclothymia. Arthritis second. Hypothyroid and high cholesterol next. Headaches resolved with menopause, but have come back. Allergic reactions to unknown things about same time as headaches.

    Reply

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Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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