eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

  Tools
All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms       Ask question       Write review       Answered/ Unanswered       Reviews       Community

Review: taking Tramadol and Methotrexate together

Summary: drug interactions are reported among people who take Tramadol and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Tramadol and Methotrexate. It is created by eHealthMe based on reports of 3,220 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Tramadol and Methotrexate >>>

What are the drugs

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from 41,556 Tramadol users)

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,243 Methotrexate users)

On Feb, 13, 2015: 3,220 people who take Tramadol, Methotrexate are studied

Tramadol, Methotrexate outcomes

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol is effective50.00%
(1 of 2 people)
33.33%
(3 of 9 people)
25.00%
(2 of 8 people)
20.00%
(2 of 10 people)
26.67%
(4 of 15 people)
11.11%
(1 of 9 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
Methotrexate is effective0.00%
(0 of 3 people)
25.00%
(3 of 12 people)
16.67%
(1 of 6 people)
11.11%
(1 of 9 people)
26.67%
(4 of 15 people)
0.00%
(0 of 5 people)
50.00%
(2 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Febrile NeutropeniaDyspnoeaNauseaCerebrovascular AccidentPulmonary EmbolismArthritis BacterialCellulitisNausea
Mucosal InflammationAnaemiaEmbolismHaematomaEmbolismSystemic Lupus ErythematosusHip FractureArthralgia
ThrombocytopeniaVomitingCoronary Artery EmbolismLumbar Spinal StenosisCoronary Artery EmbolismAkathisiaImpaired HealingPain
Weight DecreasedLeukopeniaPulmonary EmbolismGeneral Physical Health DeteriorationBone CystAffect LabilityPancytopeniaHeadache
Febrile Bone Marrow AplasiaPneumoniaArterial ThrombosisBasal Cell CarcinomaAstheniaLung Neoplasm MalignantSepsisVomiting
LeukopeniaNauseaVomitingPneumonia NosArterial ThrombosisGastrointestinal InflammationLung Cancer MetastaticPyrexia
PneumoniaPleural EffusionHepatitis BDrug IneffectiveAlanine Aminotransferase IncreasedHypertensionOedema PeripheralFatigue
VomitingJaundiceDehydrationPancreatitisLower Respiratory Tract InfectionCytomegalovirus Test PositiveFallDyspnoea
FatigueGamma-glutamyltransferase IncreasedHepatitis B PositivePulmonary TuberculosisPneumoniaEnterocolitis HaemorrhagicBack PainPneumonia
Renal Failure AcuteDecreased AppetiteHepatic FailureAlcohol PoisoningNauseaLower Gastrointestinal HaemorrhagePyrexiaDiarrhoea

Drug effectiveness by gender :

FemaleMale
Tramadol is effective22.73%
(10 of 44 people)
36.36%
(4 of 11 people)
Methotrexate is effective18.18%
(8 of 44 people)
30.00%
(3 of 10 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPneumonia
ArthralgiaDyspnoea
PainPyrexia
VomitingHeadache
HeadacheArthralgia
FatigueNausea
DiarrhoeaDrug Ineffective
FallDizziness
PyrexiaRheumatoid Arthritis
AstheniaAnaemia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol is effectiven/an/a33.33%
(1 of 3 people)
0.00%
(0 of 5 people)
18.75%
(3 of 16 people)
7.14%
(2 of 28 people)
22.73%
(5 of 22 people)
20.00%
(3 of 15 people)
Methotrexate is effectiven/an/a0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
13.33%
(2 of 15 people)
8.00%
(2 of 25 people)
13.04%
(3 of 23 people)
20.00%
(3 of 15 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Limb Reduction DefectSomnolenceWeight DecreasedHeadacheFatigueNauseaArthralgiaPain
Complications Of Maternal Exposure To Therapeutic DrugsAbdominal PainVomitingNauseaNauseaArthralgiaNauseaFall
Bone Development AbnormalGraft Versus Host DiseaseFebrile NeutropeniaArthralgiaHeadacheHeadachePainArthralgia
SepsisFebrile Bone Marrow AplasiaPyrexiaVomitingRectal HaemorrhageDiarrhoeaDrug Ineffective
Vision BlurredMucosal InflammationBack PainDizzinessChest PainVomitingPneumonia
IrritabilityPyrexiaVomitingArthralgiaPainHeadacheAsthenia
Depressed Level Of ConsciousnessDehydrationPainCoughPneumoniaDyspnoeaAnaemia
TachycardiaDecreased AppetiteMulti-organ FailureMyalgiaAstheniaAbdominal PainAtrial Fibrillation
AgitationPregnancyAbdominal PainFallFatiguePyrexiaNausea
Partial SeizuresPulmonary OedemaParaesthesiaAbdominal Pain UpperPyrexiaPain In ExtremityPyrexia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Tramadol and Methotrexate on

Do you take Tramadol and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Methotrexate
- support group for people who take Methotrexate
- support group for people who take Tramadol

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • What are healthy steps should i take against cronary artery disease
    I feel sharp pains just below my left breast . At first i thought it was a breast cancer but ii ran a test that cancelled that out. Now, i strongly suspect a coronary artery disease. I also feel similar pains at my feets, restlessness at night and a bit of hallicinations at night. I also have high blood pressure.
  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Can tramadol usage cause a low white blood cell count?
    Low WBC of 2.7 on 10/21/15 and then 3.8 on 12/08/15
    Can these things be connected?
  • Would the tinnitus abate with if i discontinue methotrexate?
    I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
  • Can i take humira while i still have pinpoint red spots on my skin? i have been told to stop the methotrextrate and they started me on prednisone to clear it up, i am scheduled to start humira.
    I have been diagnosed with R/A and started taking Methotrextate and Folic Acid. I began to break out like I had the measles. Was told it was a reaction to the methotrextate. I was taken off of it and given a large dose of prednisone. My question is I am scheduled to start taking Humira injections and I have been off of the methotrextate 24 days and it has not cleared up yet. Is is safe to start the Humira injections?

More questions for: Methotrexate, Tramadol

You may be interested at these reviews (Write a review):

  • Muscle weakness from methotrexate
    I'm 61 and have taken methotrexate for 25 yrs. I've always done well with my blood results etc. Lately I've been having problems pushing a grocery cart. My arm muscles are so weak!
  • Having leg cramps after 2 years on enbrel
    Started having leg cramps after using Enbrel for almsot 2 years. They start the day I give the injection and have lasted 1-3 days waking me several time in the middle of the night.
  • Roaring in the ears from tramadol (taken with dexamethasone)
    It seems the roaring in my right ear happens more around taking the tramadol (2-3/day). Of course, I have a (5) day regiment of dexamethasone at (2/day) so maybe there's a connection. This was prescribed by my GP ( highly regarded) for severe lower back bulging disc pain and down left leg. Also prescribed tizanidine for muscle spasms and gabapentin for, maybe nerve swelling? Both at 2/day but I take less of these two.

    Back pain much better but have the roaring in right ear and can't sleep much. Also doing the Dr recommended exercises daily. Will follow up with chiropractic if this doesn't get me there.

    This is a chronic condition, maybe 20 years, no specific injury, just an accumulation of doing dumb things in my youth.
  • Tramadol and severe rls and restless arms
    After back surgery I was prescribed Tramadol for pain. After about a month I developed severe RLS and also restless arms that seemed to make it hard to breath. Like a weight on my chest. I noticed that after taking the Tramadol, only at night for sleep, the restless symptoms got worse for about an hour and then settled down some. Before long there was no settling down. My pain after several months being better in my back I, not liking to take medicine period, decided to stop the Tramadol. To my surprise my RLS came to almost a complete halt. After about a week it was gone completely.
  • Mom died of stomach blockage while on tramadol
    my mom was taking tramadol for hip pain. she went in the hospital for a hip replacement and died 3 days after the surgery in the hospital from an intestinal blockage

More reviews for: Methotrexate, Tramadol

Comments from related studies:

  • From this study (11 months ago):

  • The abnormal dreams & mild hallucinations came only after starting the methylprednisolone a few days ago. They happen primarily when I am sleeping. I woke up last night with very unusual dreams & head/brain pain, and was quite concerned. I had taken 1 methylprednisolone & 1 cymbalta before bed. Earlier in the day, I had taken 2 methylprednisolone & 2 tramadol before a nap, and had similar, though not as severe issues. Trying to figure out what the interaction problem is. I did not take the muscle relaxant (cyclopenzaprine) before bed since I started the cortico steroid pack.

    Reply

    britsarmymom on Apr, 26, 2014:

    Mother just survived near brush with respiratory arrest. Hallucinated at night on Tramadol, argumentative with RN who reported her to MD. He planned to ADD Seroquel 25 mg to Tramadol, Neurontin, Remeron and Ativan in rehab facility. She declined Tramadol and Seroquel and was still so sedated her pulse ox went down to 84 with long periods of apnea and need for constant obs with frequent rousing for airway. MAJOR struggle with RN to get 02 and MD agreed to no more Tramodol at night and absolutely no Seroquel. How many elderly are lost this way?

    Reply

  • From this study (12 months ago):

  • suspicious lung nodule seen in x-ray, going in for a cat scan

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

About - Terms of service - Privacy policy - Press - Testimonials - Contact us

 
© 2015 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.