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Home > Tramadol > Methotrexate > Tramadol and Methotrexate

Review: Tramadol and Methotrexate

This review analyzes the effectiveness and drug interactions between Tramadol and Methotrexate. It is created by eHealthMe based on reports of 3,219 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tramadol and Methotrexate >>>

What are the drugs

Tramadol (latest outcomes from 41,482 users) has active ingredients of tramadol hydrochloride. It is often used in pain.

Trend of tramadol reports

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

On Nov, 14, 2014: 3,219 people who take Tramadol, Methotrexate are studied

Tramadol, Methotrexate outcomes

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol is effective50.00%
(1 of 2 people)
33.33%
(3 of 9 people)
25.00%
(2 of 8 people)
20.00%
(2 of 10 people)
28.57%
(4 of 14 people)
11.11%
(1 of 9 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
Methotrexate is effective0.00%
(0 of 3 people)
25.00%
(3 of 12 people)
16.67%
(1 of 6 people)
11.11%
(1 of 9 people)
26.67%
(4 of 15 people)
0.00%
(0 of 4 people)
50.00%
(2 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Febrile NeutropeniaDyspnoeaNauseaCerebrovascular AccidentPulmonary EmbolismArthritis BacterialCellulitisNausea
Mucosal InflammationAnaemiaEmbolismHaematomaCoronary Artery EmbolismSystemic Lupus ErythematosusHip FractureArthralgia
ThrombocytopeniaVomitingCoronary Artery EmbolismLumbar Spinal StenosisEmbolismAkathisiaImpaired HealingPain
Weight DecreasedLeukopeniaPulmonary EmbolismGeneral Physical Health DeteriorationLower Respiratory Tract InfectionAffect LabilityPancytopeniaHeadache
Febrile Bone Marrow AplasiaPneumoniaArterial ThrombosisBasal Cell CarcinomaAstheniaHypertensionSepsisVomiting
LeukopeniaNauseaVomitingPneumonia NosArterial ThrombosisGastrointestinal InflammationLung Cancer MetastaticPyrexia
PneumoniaPleural EffusionHepatitis BDrug IneffectiveAlanine Aminotransferase IncreasedLung Neoplasm MalignantOedema PeripheralFatigue
VomitingJaundiceDehydrationPancreatitisBone CystEnterocolitis HaemorrhagicFallDyspnoea
FatigueGamma-glutamyltransferase IncreasedHepatitis B PositivePulmonary TuberculosisPneumoniaCytomegalovirus Test PositiveBack PainPneumonia
Renal Failure AcuteDecreased AppetiteHepatic FailureAlcohol PoisoningNauseaLower Gastrointestinal HaemorrhagePyrexiaDiarrhoea

Drug effectiveness by gender :

FemaleMale
Tramadol is effective22.73%
(10 of 44 people)
40.00%
(4 of 10 people)
Methotrexate is effective18.18%
(8 of 44 people)
33.33%
(3 of 9 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPneumonia
ArthralgiaDyspnoea
PainPyrexia
VomitingArthralgia
HeadacheHeadache
FatigueNausea
DiarrhoeaRheumatoid Arthritis
FallDrug Ineffective
PyrexiaDizziness
AstheniaAnaemia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol is effectiven/an/a33.33%
(1 of 3 people)
0.00%
(0 of 5 people)
18.75%
(3 of 16 people)
7.41%
(2 of 27 people)
22.73%
(5 of 22 people)
20.00%
(3 of 15 people)
Methotrexate is effectiven/an/a0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
13.33%
(2 of 15 people)
8.33%
(2 of 24 people)
13.04%
(3 of 23 people)
20.00%
(3 of 15 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Limb Reduction DefectSomnolenceWeight DecreasedHeadacheFatigueNauseaArthralgiaPain
Complications Of Maternal Exposure To Therapeutic DrugsAbdominal PainVomitingNauseaNauseaArthralgiaNauseaFall
Bone Development AbnormalGraft Versus Host DiseaseFebrile NeutropeniaArthralgiaHeadacheHeadachePainArthralgia
SepsisFebrile Bone Marrow AplasiaPyrexiaVomitingRectal HaemorrhageDiarrhoeaDrug Ineffective
Vision BlurredMucosal InflammationBack PainDizzinessChest PainVomitingPneumonia
IrritabilityPyrexiaVomitingArthralgiaPneumoniaHeadacheAsthenia
Depressed Level Of ConsciousnessDehydrationPainCoughPainDyspnoeaAnaemia
TachycardiaDecreased AppetiteMulti-organ FailureMyalgiaAstheniaAbdominal PainAtrial Fibrillation
AgitationPregnancyAbdominal PainFallFatiguePyrexiaNausea
Partial SeizuresPulmonary OedemaParaesthesiaAbdominal Pain UpperPyrexiaPain In ExtremityPyrexia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Methotrexate
- support group for people who take Methotrexate
- support group for people who take Tramadol

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Methotrexate, Tramadol

You may be interested at these reviews (Write a review):

  • No noticeable effects
    (Posted by a 45 year old woman who has Spinal Stenosis, Degenerative Disc Disease, Spondylosis, End Term Osteoarthritis, and takes Red Panax Ginseng, Tramadol )
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.

  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...

  • I wish i had never taken ambien
    (Posted by a 43 year old woman who has Fibromyalgia, and takes Savella, Lyrica, Synthroid, Effexor, Tramadol, Duragesic-50, Flexeril, Ambien)
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered A ...

  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...

  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

More reviews for: Methotrexate, Tramadol

Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Methotrexate, Tramadol

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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