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Review: taking Tramadol and Methotrexate together

Summary: drug interactions are reported among people who take Tramadol and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Tramadol and Methotrexate. It is created by eHealthMe based on reports of 3,221 people who take the same drugs from FDA and social media, and is updated regularly.

 

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On Apr, 16, 2015: 3,221 people who take Tramadol, Methotrexate are studied

Tramadol, Methotrexate outcomes

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol is effective50.00%
(1 of 2 people)
33.33%
(3 of 9 people)
25.00%
(2 of 8 people)
20.00%
(2 of 10 people)
26.67%
(4 of 15 people)
20.00%
(2 of 10 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
Methotrexate is effective0.00%
(0 of 3 people)
25.00%
(3 of 12 people)
16.67%
(1 of 6 people)
11.11%
(1 of 9 people)
25.00%
(4 of 16 people)
0.00%
(0 of 5 people)
50.00%
(2 of 4 people)
n/a

Drug effectiveness by gender :

FemaleMale
Tramadol is effective22.73%
(10 of 44 people)
41.67%
(5 of 12 people)
Methotrexate is effective18.18%
(8 of 44 people)
27.27%
(3 of 11 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol is effectiven/an/a33.33%
(1 of 3 people)
0.00%
(0 of 5 people)
18.75%
(3 of 16 people)
7.14%
(2 of 28 people)
22.73%
(5 of 22 people)
25.00%
(4 of 16 people)
Methotrexate is effectiven/an/a0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
13.33%
(2 of 15 people)
8.00%
(2 of 25 people)
13.04%
(3 of 23 people)
18.75%
(3 of 16 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Febrile NeutropeniaDyspnoeaNauseaCerebrovascular AccidentPulmonary EmbolismArthritis BacterialCellulitisNausea
Mucosal InflammationAnaemiaEmbolismHaematomaCoronary Artery EmbolismSystemic Lupus ErythematosusHip FractureArthralgia
ThrombocytopeniaVomitingCoronary Artery EmbolismLumbar Spinal StenosisEmbolismAkathisiaImpaired HealingPain
Weight DecreasedLeukopeniaPulmonary EmbolismGeneral Physical Health DeteriorationAstheniaAffect LabilityPancytopeniaHeadache
Febrile Bone Marrow AplasiaPneumoniaArterial ThrombosisBasal Cell CarcinomaAlanine Aminotransferase IncreasedEnterocolitis HaemorrhagicSepsisVomiting
LeukopeniaNauseaVomitingPneumonia NosPneumoniaLung Neoplasm MalignantLung Cancer MetastaticPyrexia
PneumoniaPleural EffusionHepatitis BDrug IneffectiveArterial ThrombosisCytomegalovirus Test PositiveOedema PeripheralFatigue
VomitingJaundiceDehydrationPancreatitisBone CystHaemorrhagic AnaemiaFallDyspnoea
FatigueGamma-glutamyltransferase IncreasedHepatitis B PositivePulmonary TuberculosisLower Respiratory Tract InfectionHypertensionBack PainPneumonia
Renal Failure AcuteDecreased AppetiteHepatic FailureAlcohol PoisoningNauseaGastrointestinal InflammationPyrexiaDiarrhoea

Most common drug interactions by gender * :

FemaleMale
NauseaPneumonia
ArthralgiaDyspnoea
PainPyrexia
VomitingArthralgia
HeadacheHeadache
FatigueNausea
DiarrhoeaRheumatoid Arthritis
FallDizziness
PyrexiaDrug Ineffective
AstheniaAnaemia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Limb Reduction DefectSomnolenceWeight DecreasedHeadacheFatigueNauseaArthralgiaPain
Complications Of Maternal Exposure To Therapeutic DrugsAbdominal PainVomitingNauseaNauseaArthralgiaNauseaFall
Bone Development AbnormalGraft Versus Host DiseaseFebrile NeutropeniaArthralgiaHeadacheHeadachePainArthralgia
SepsisFebrile Bone Marrow AplasiaPyrexiaVomitingRectal HaemorrhageDiarrhoeaDrug Ineffective
Vision BlurredMucosal InflammationBack PainDizzinessChest PainVomitingPneumonia
IrritabilityPyrexiaVomitingArthralgiaPainHeadacheAnaemia
Depressed Level Of ConsciousnessDehydrationPainCoughPneumoniaDyspnoeaAsthenia
TachycardiaDecreased AppetiteMulti-organ FailureMyalgiaAstheniaAbdominal PainAtrial Fibrillation
AgitationPregnancyAbdominal PainFallFatiguePyrexiaNausea
Partial SeizuresPulmonary OedemaParaesthesiaAbdominal Pain UpperPyrexiaPain In ExtremityDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Methotrexate
- support group for people who take Tramadol

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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