Review: Tramadol and Paxil drug interactions
This review analyzes the interactions between Tramadol and Paxil. It is created by eHealthMe based on 1,622 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Tramadol (latest outcomes from 41,165 users) has active ingredients of tramadol hydrochloride. It is often used in pain.
Paxil (latest outcomes from 70,148 users) has active ingredients of paroxetine hydrochloride. It is often used in depression.
On Mar, 6, 2014: 1,622 people who reported to have interactions when taking Tramadol, Paxil are studied
Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Paxil (paroxetine hydrochloride)
Most common interactions experienced by people in the use of Tramadol, Paxil:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Dyspnoea (difficult or laboured respiration)||591|
|Arthralgia (joint pain)||572|
|Headache (pain in head)||307|
|Nausea (feeling of having an urge to vomit)||294|
Most common interactions experienced by people in long term use of Tramadol, Paxil:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Arthralgia (joint pain)||102|
|Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)||77|
|Incontinence (lack of moderation or self-control)||76|
|Malaise (a feeling of general discomfort or uneasiness)||75|
|Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)||74|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
Top co-used drugs for these people * :
- Paroxetine hcl
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Paxil (paroxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Tramadol is used in:
- Paxil is used in:
Other drugs that are used to treat the same conditions:
- Tramadol alternatives:
- Paxil alternatives:
Comments from related studies:
From this study (2 years ago):
From this study (2 years ago):
From this study (3 years ago):
Karen on Aug, 15, 2011:
I do not take any medications my BP is usually within normal range of 115 over 78. After taking aloe vera tablets. One today and one yesterday...I am experiencing increased BP and heart rate. It did however, take my heartburn away. I will not take anymore aloe vera orally. Will only use it on my skin from here on out. Not liking the feeling that it gives me.
Brandy on Jun, 30, 2012:
I am 29 year old female..I took one capsule at midnight two days ago. I have been experiencing extreme stomach cramps and diarrhea. I can not keep any food in my system. I have been miserable for two days now. I will never take these pills again. I've tried to counter act the side affect with pepto but as of right now that's not working. I am trying to stay hydrated because it's pure liquid coming out. This is the worst feeling every...
randytrain on Dec, 17, 2011:
This isn't about interaction between paxil (which I quit taking 10 years ago). This is about Ultram/tramadol. Either someone is afraid to admit it or they're just lying to themselves. The report I just viewed said only about 1% get addicted. Well.... I guess I'm special. Put me in the + 10 years of dependency "group." Cannot function without it everyday, and I mean a lot of it. I feel it is burning up my internal organs because I'm hot when it's freezing outside. Try to quit? Nothing I've seen on TV about withdrawal from any drug... heroin, coke, whatever (none of which I've every had any experience with) can stand up to what happens to me when I quit taking it. The illness, which is Flu X 100 times, plus pain beyond my ability to withstand, plus diahria, excess saliva and nose running... is something I cannot take. I've gone 3 weeks several times and still it does not subside. This stuff was given to me in place of hydrocodone after a severe injury to all 8 of my fingers. I was given lots of samples and told to go home after a year of 5 surgeries and therapy that made me faint, from the pain, constantly. Those samples were the worst thing that ever happened to me. My personality is different and I can NOT stop. TRAMADOL IS THE BAIN OF MY EXISTENCE and has cost me everything.
slurred speach, incoherent, lethargic
Can you answer these questions (what is this?):
- By patita: Could paxil long use (more than 10 years) be causing parkinsonism
I have been taking Paxil during about 12 years s/o stopping prescribed for my chronic depression. 5 years ago I was diagnosed parkinson disease. I have always wondered if Paxil could have caused it.
- By Becky: Will tramadol cause rapid heart beat?
I have been taking Tramadol for 1 1/2 years and within the past 6 weeks have developed an unexplained rapid heart beat. The heart monitor I wore for 24 hours indicated a premature heart but after a month the EKG was normal. I was taken off of Toprol and instructed to take magnesium (400) milligrams ...
- By mda1270: Can tramadol and meloxicam be taken together?
What is causing my pain? The years of muscale atrophy or the joints
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I've Taking naproxen 500mg twice a day for 3 weeks on a course for 6 months, I've been having horrific dreams worse than horrer movies, the most recent is involving my ex & current partner where I had a psychotic stalker (my ex) switched around because in the dream I dump my partner for my ex, well ...
- By luvubug: Burning mouth syndrome
I went into a local emergency room for a sore throat with pustules and difficulty swallowing, i was given Tramadol for pain through my iv. About 2 days later i woke up with a very blistery tongue, which was mildly painful as the day progressed i felt like i had been eating habanero peppers all day.. ...
- By medtech56: Nexium and feeling cold
I took Nexium (1 40mg capsule) and approximately 45 minutes later, I felt extremely cold. I could not get warm, even though I put on a polartec jacket and sat near a heater. I also was extremely nauseated at the same time. About 30 minutes after the incident began, it ended. I no longer was ...
Recent related drug studies:
- A study of drug interactions between Geodon, Risperdal, Clonazepam, Paxil, Flexeril, Tramadol Hydrochloride, Relafen, Zanaflex, Asmanex Twisthaler, Albuterol, Levothyroxine Sodium - 0.125MG, Atenolol, Hydrochlorothiazide, Topamax, Omeprazole, Promethazine Hydrochloride Plain, Ambien, Valtrex for a patient with Bipolar Mania, Mental Disorder, Osteoarthritis, Degenerative Joint Disease, Brain Damage, Asthma Late Onset, Asthmatic Crisis, Thyroid Disorder, Left Ventricular Hypertrophy, Heart Disease, Seizures, Stomach Ulcer, Nausea, Insomnia, Preventive Health Care. The patient has Geodon, Clonazepam - 1mg, Topamax - 25mg
- A study of drug interactions between Paxil, Xyzal, Ultram Er for a patient with Pain, Allergies. The patient has Pain In Limb
- A study of drug interactions between Ultram, Paxil for a patient with Pain, Depression.
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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