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Review: Tylenol W/ Codeine and Zofran

This review analyzes the effectiveness and drug interactions between Tylenol W/ Codeine and Zofran. It is created by eHealthMe based on reports of 268 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Tylenol W/ Codeine and Zofran >>>

What are the drugs

Tylenol w/ codeine (latest outcomes from 8,040 users) has active ingredients of acetaminophen; codeine phosphate. It is used in pain.

Zofran (latest outcomes from 865 users) has active ingredients of ondansetron hydrochloride. It is used in nausea.

On Aug, 17, 2014: 268 people who take Tylenol W/ Codeine, Zofran are studied

Tylenol W/ Codeine, Zofran outcomes

Drug combinations in study:
- Tylenol W/ Codeine (acetaminophen; codeine phosphate)
- Zofran (ondansetron hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tylenol W/ Codeine is effective0.00%
(0 of 1 people)
(0 of 1 people)
Zofran is effectiven/a100.00%
(1 of 1 people)
(1 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
VomitingPulmonary Embolismn/aAbdominal Pain Uppern/aAbdominal Pain UpperAcute Myeloid LeukaemiaVomiting
Atrial FibrillationDiarrhoeaGallbladder InjuryGallbladder InjuryNausea
Hepatic NecrosisUrinary Tract InfectionCholecystitis ChronicCholecystitis ChronicAnaemia
Alanine Aminotransferase IncreasedPyrexiaPyrexia
Acute Myeloid LeukaemiaOral DisorderNeutropenia
OverdoseClostridium Difficile ColitisPulmonary Embolism
PneumoniaLung DisorderAbdominal Pain
NeutropeniaRetinal OedemaFatigue

Drug effectiveness by gender :

Tylenol W/ Codeine is effective0.00%
(0 of 2 people)
Zofran is effective66.67%
(2 of 3 people)

Most common drug interactions by gender * :

NauseaAtrial Fibrillation
PyrexiaHepatic Necrosis
Abdominal Pain UpperAlanine Aminotransferase Increased
DehydrationPulmonary Embolism
Cholecystitis ChronicOverdose
AnaemiaAbdominal Pain

Drug effectiveness by age :

Tylenol W/ Codeine is effectiven/an/a0.00%
(0 of 1 people)
(0 of 1 people)
Zofran is effectiven/an/a0.00%
(0 of 1 people)
(1 of 1 people)
(1 of 1 people)

Most common drug interactions by age * :

n/aEpidermal NecrolysisVomitingAbdominal PainFebrile NeutropeniaFatigueAbdominal PainVomiting
HeadacheCholecystitis ChronicIncoherentDehydrationRetinal HaemorrhagePain In ExtremityAtrial Fibrillation
Abdominal PainAbdominal Pain UpperHypertensionAnaemiaVisual Acuity ReducedMusculoskeletal DiscomfortHepatic Necrosis
IrritabilityAnxietyHepatomegalyFanconi SyndromeOptic AtrophyConstipationAcidosis
Pain In ExtremityNauseaDisorientationNauseaHypoxiaNauseaAlanine Aminotransferase Increased
AnaemiaSeptic ShockFatigueHaemolytic AnaemiaDyspnoeaSplinter HaemorrhagesOverdose
NeutropeniaAbdominal TendernessHeadacheFatigueNauseaArterial ThrombosisPulmonary Embolism
LymphopeniaDroolingLung DisorderAnxietyVision BlurredInfarctionDyspnoea
Febrile NeutropeniaAplasiaNeurotoxicityPainDisease ProgressionContusionSepsis
Sensation Of Foreign BodyPurpura NosSoporGallbladder DisorderCerebrovascular AccidentDevice Related InfectionNeutropenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Tylenol W/ Codeine and Zofran
- group for people who take Tylenol W/ Codeine
- group for people who take Zofran

Can you answer these questions (what is this?):

More questions for: Tylenol W/ Codeine, Zofran

You may be interested at these reviews (what is this?):

  • Pulse increase with tylenol w/ codeine/caffeine no. 3
    Knee arthroscopic surgery at 2pm Took one tablet with food at 2am that night (next morning actually) before going to bed. Pulse increased to 88-92 after about 20-30 min (taken for 15 secs and multiplied)(taken a few times) Possible interaction with chocolate milk??? Next morning at 8am pul ...

  • I got pneumonia while taking topamax, obvious correlation
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and ...

More reviews for: Tylenol W/ Codeine, Zofran

Complete drug side effects:

On eHealthMe, Tylenol W/ Codeine (acetaminophen; codeine phosphate) is often used to treat pain. Zofran (ondansetron hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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