Review: Valproate and Topiramate
This review analyzes the effectiveness and drug interactions between Valproate and Topiramate. It is created by eHealthMe based on 727 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.
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On Apr, 6, 2014: 727 people who reported to have interactions when taking Valproate Sodium, Topiramate are studied
Drug combinations in study:
- Valproate Sodium (valproate sodium)
- Topiramate (topiramate)
Most common interactions experienced by people in the use of Valproate Sodium, Topiramate:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)||176|
|Somnolence (a state of near-sleep, a strong desire for sleep)||151|
|Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)||120|
|Renal Failure (kidney dysfunction)||109|
|Grand Mal Convulsion (a type of generalized seizure that affects the entire brain)||86|
Most common interactions experienced by people in long term use of Valproate Sodium, Topiramate:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)||24|
|Platelet Count Decreased||24|
|Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash)||20|
|Thyroiditis (inflammation of thyroid gland)||20|
|Myocarditis (inflammation of heart muscle myocardium)||20|
|White Blood Cell Count Decreased||16|
|Cardiomegaly (increased size of heart than normal)||12|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Drug exposure during pregnancy
- Status epilepticus
- Partial seizures
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Valproate Sodium (valproate sodium) is often used to treat epilepsy. Topiramate (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Valproate sodium is used in:
- Topiramate is used in:
Other drugs that are used to treat the same conditions:
- Valproate sodium alternatives:
- Topiramate alternatives:
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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