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Review: Vicodin and Tramadol





Summary: drug interactions are reported among people who take Vicodin and Tramadol together.

This review analyzes the effectiveness and drug interactions between Vicodin and Tramadol. It is created by eHealthMe based on reports of 4,302 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Vicodin and Tramadol >>>

What are the drugs

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Vicodin 35,316 users)

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (view latest outcomes from 41,501 users)

On Dec, 14, 2014: 4,302 people who take Vicodin, Tramadol are studied

Vicodin, Tramadol outcomes

Drug combinations in study:
- Vicodin (acetaminophen; hydrocodone bitartrate)
- Tramadol (tramadol hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vicodin is effective43.75%
(14 of 32 people)
37.50%
(9 of 24 people)
35.29%
(6 of 17 people)
25.81%
(8 of 31 people)
46.94%
(23 of 49 people)
52.38%
(11 of 21 people)
33.33%
(3 of 9 people)
100.00%
(1 of 1 people)
Tramadol is effective19.35%
(6 of 31 people)
16.67%
(5 of 30 people)
0.00%
(0 of 23 people)
20.59%
(7 of 34 people)
29.27%
(12 of 41 people)
31.25%
(5 of 16 people)
28.57%
(2 of 7 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Chest PainPainDepressionInjuryAnxietyAnxietyPainPain
Cardiac ArrestDepressionFatigueChest PainDepressionDepressionConstipationNausea
Loss Of ConsciousnessDrug DependenceHallucination, AuditoryMyocardial InfarctionSuicidal IdeationPainAbdominal PainAnxiety
DyspnoeaDrug IneffectiveDrug DependenceInsomniaNauseaInsomniaDiarrhoeaBack Pain
Intervertebral Disc ProtrusionMental Status ChangesCognitive DisorderEmotional DistressLoss Of ConsciousnessEmotional DistressTearing - IncreasedDepression
Drug IneffectiveInjuryCerebrovascular AccidentDepressionPulmonary EmbolismLoss Of ConsciousnessUrinary Tract Infection ViralDyspnoea
Pain In ExtremityVomitingSomnolenceAnxietySuicide AttemptSuicidal IdeationHigh Blood SugarArthralgia
FallDyspnoeaDizzinessPainPainFallFatigue - ChronicHeadache
Road Traffic AccidentFatigueDisorientationHypoaesthesiaDeep Vein ThrombosisFatigueCholecystitis ChronicFatigue
Back PainNauseaPost-thoracotomy Pain SyndromeAngina PectorisFatigueMyocardial InfarctionGastrooesophageal Reflux DiseaseChest Pain

Drug effectiveness by gender :

FemaleMale
Vicodin is effective45.04%
(59 of 131 people)
30.77%
(16 of 52 people)
Tramadol is effective23.02%
(29 of 126 people)
14.81%
(8 of 54 people)

Most common drug interactions by gender * :

FemaleMale
PainNausea
AnxietyPain
NauseaAnxiety
Back PainDyspnoea
DepressionDepression
FallBack Pain
HeadacheChest Pain
FatigueInsomnia
ArthralgiaVomiting
DyspnoeaMyocardial Infarction

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Vicodin is effectiven/an/a0.00%
(0 of 3 people)
20.00%
(7 of 35 people)
22.58%
(21 of 93 people)
34.43%
(21 of 61 people)
20.45%
(18 of 88 people)
25.81%
(8 of 31 people)
Tramadol is effectiven/an/a33.33%
(1 of 3 people)
14.71%
(5 of 34 people)
10.11%
(9 of 89 people)
11.48%
(7 of 61 people)
10.23%
(9 of 88 people)
20.00%
(6 of 30 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
ConvulsionNon-accidental Injury To ChildCholecystitis ChronicPainAnxietyPainAnxietyPain
Accidental Drug Intake By ChildHaemorrhage NosNauseaAnxietyDepressionBack PainPainDyspnoea
Cardio-respiratory ArrestOverdose NosGallbladder DisorderCholelithiasisPainNauseaNauseaFall
ApnoeaCardio-respiratory ArrestVomitingCholecystitis ChronicNauseaDepressionEmotional DistressBack Pain
ComaWhite Blood Cell Count DecreasedAbdominal PainNauseaHeadacheArthralgiaInsomniaNausea
DeathUpper Respiratory Tract InfectionPainInjuryArthralgiaHeadacheDepressionFatigue
Respiratory ArrestBlood Pressure DecreasedCholelithiasisDeep Vein ThrombosisPain In ExtremityChest PainHeadacheAsthenia
Foetal Exposure During PregnancyHeart Rate IncreasedAnxietyVomitingChest PainAnxietyAnaemiaAnxiety
Congenital Aortic AnomalyRhinorrhoeaInjuryHeadacheDrug DependencePain In ExtremityCoughWeight Decreased
Loss Of ConsciousnessAccidental ExposureDeep Vein ThrombosisPulmonary EmbolismDizzinessFatigueFatigueArthralgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Vicodin and Tramadol?

You are not alone! Join a related mobile support group:
- support group for people who take Vicodin and Tramadol
- support group for people who take Tramadol
- support group for people who take Vicodin

Can you answer these questions (Ask a question):

  • Can i take diclofenac sodium mispoprostol with tramadol hcl?
    I have bad arthritis in my hips - very painful and affecting my quality of life. My doctor like to prescribe pills. He has given me Diclofenac Sodium Mispoprostal and Tramadol HCL. I have experienced minimal side effects i.e.: drowsiness but thats about it. I just want to be sure that I can take these drugs together.
  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Does anyone experience heart palpitations causedby their acid reflux ?
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
  • I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (3 answers)
    Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
    I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.
  • Can you loose weight while taking hydroxyzine?
    Hydroxyzine has been my life saver but I have noticed a gradual increase in weight. My blood pressure has also gone up. I don't have the increased hunger but what scares me is I am not eating more than I normally do. I do not eat breakfast. I have a Glucerna at lunch and then dinner, protein potatoes/rice and veggies, sometimes pasta nothing huge and a snack at night. Maybe a small bowl of ice cream but not every night. I do not drink soda, lots of water and with dinner a large glass of apple juice. I have noticed every year I put on a little bit more weight. I was tested for my thyroid and it is normal. I haven't started an avid work out program. Doing high intense impact will not work due to my IC. I would like to try power walking. Anyone else experience any of these issues?

More questions for: Tramadol, Vicodin

You may be interested at these reviews (Write a review):

  • No noticeable effects
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
  • Heavy sweating during sleep
    Pain killers like Tylenol 3, vicodin 20 years, Valium and Soma 12 years. Sweat heavy during sleep.
  • Seizure patient was on depakote for 16 years now on keppra 1500 mg.
    I am 28 years old and been off depakote for 5 months. I started keppra to control my seizure disorder, which works great. But for the past year I have developed osteoarthritis in my thoracic, si joints, and lumbar. I get alot of muscle hypersensitivity and pain. Can any of this be due to long term effects of seizure meds?
  • Prednisone mixed results-it lets me breath
    have been on prednisone now for 3 years straight. Am taking 30mg a day just to breath. every time i have tried to taper off i have ended up in the emergency room unable to breath. That has been 7 times in the last year. I am 49 years old and was in good health 3-4 years ago. got a cough and it has been down hill.Prednisone worked great at first but then it starts to destroy the body.Had nasal passage surgery(waste of time)have broken many ribs from coughing.painful.when you are on prednisone your body takes 3-5 times longer to heal.craked tailbone from a slip. have seen over 12 doctors.reasonable gueswork. My best doc which is mine says do you want to suffocate to death or let your body try and fix itself if it can. im not for suffocation at all. Just a good medicine to counter the angriness of the steroid. Any ideas i am all ears. oh ya my eyes are starting to go and my joints as well
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.

More reviews for: Tramadol, Vicodin

Comments from related studies:

  • From this study (3 months ago):

  • pain and heaviness in arms and legs, comes and goes. relieved by heat but gets worse immediately once heat is removed.

    Reply

  • From this study (4 months ago):

  • I've had 4 hip surgeries since 2012 for AVN & I've been left with chronic pain in lower back, pelvis, left hip/groin/thigh/knee & pain in right groin/thigh/knee

    Reply

  • From this study (5 months ago):

  • I am now unable to walk with my crutches, my primary doctor put in for a wheelchair. This CRPS is getting worse and worse every day and spreading to both feet both knees both legs.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Vicodin (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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