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Review: taking Vyvanse and Suboxone together

Summary: drug interactions are reported among people who take Vyvanse and Suboxone together.

This review analyzes the effectiveness and drug interactions between Vyvanse and Suboxone. It is created by eHealthMe based on reports of 51 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 12, 2015: 51 people who take Vyvanse, Suboxone are studied

Vyvanse, Suboxone outcomes

Drug combinations in study:
- Vyvanse (lisdexamfetamine dimesylate)
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vyvanse is effective37.50%
(3 of 8 people)
(5 of 10 people)
(1 of 3 people)
(4 of 4 people)
(1 of 1 people)
(1 of 1 people)
(0 of 1 people)
Suboxone is effective40.00%
(2 of 5 people)
(5 of 5 people)
(7 of 7 people)
(2 of 4 people)
(5 of 5 people)
(1 of 1 people)
(1 of 1 people)

Drug effectiveness by gender :

Vyvanse is effective52.63%
(10 of 19 people)
(5 of 9 people)
Suboxone is effective85.00%
(17 of 20 people)
(6 of 8 people)

Drug effectiveness by age :

Vyvanse is effectiven/an/an/a23.81%
(5 of 21 people)
(6 of 18 people)
(3 of 4 people)
(1 of 1 people)
Suboxone is effectiven/an/an/a42.86%
(9 of 21 people)
(12 of 19 people)
(1 of 3 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Erythema MultiformeFatigue - ChronicConfusionInsomnia ExacerbatedFeverInappropriate Affectn/aSomnolence
SomnolenceBelchingMite BiteBruxismHeadacheObsessive-compulsive DisorderLoss Of Consciousness
SedationAches And Pains In BonesHair Texture AbnormalExacerbation Of AnxietyAches And Pains In BonesDecreased Eye ContactGait Disturbance
Bone LossConfusionInfection - Hair FollicleEuphoric MoodBelchingPolydipsiaMania
Mite BiteFatigue - ChronicGastrointestinal PainExhaustion, Fatigue, Lethargy, Tiredness, WearinessImpulsive BehaviourDisturbance In Attention
Bone LossPinwormsObsessive-compulsive DisorderHeart Rate IncreasedPsychotic DisorderAggression
Infection - Hair FollicleHeart Rate IncreasedInappropriate AffectSweating - ExcessiveIntentional Overdose
Hair Texture AbnormalSweating - ExcessiveImpulsive BehaviourAppetite DecreasedDrug Intolerance
HeadacheAppetite DecreasedSerotonin SyndromeConstipationDyspnoea
Exacerbation Of AnxietyConstipationPsychotic DisorderAsthenia

Most common drug interactions by gender * :

Gait DisturbanceDrug Intolerance
Loss Of ConsciousnessIntentional Overdose
Drug ToxicityAggression
DizzinessImpaired Driving Ability
HallucinationInfection - Hair Follicle
Drug DiversionDrug Ineffective
ConstipationAbdominal Pain Upper

Most common drug interactions by age * :

n/an/an/aImpaired Driving AbilityAches And Pains In BonesObsessive-compulsive DisorderFeeling Abnormaln/a
Drug IntoleranceBelchingDrug Effect DecreasedOedema Peripheral
Intentional OverdoseBack DisorderLethargyConstipation
AggressionAppetite DecreasedIrritabilityAsthenia
Obsessive-compulsive DisorderDrug Screen False PositiveDepressionPeriorbital Oedema
SedationSweating - ExcessiveElectric ShockDisturbance In Attention
Drug IneffectivePinwormsDyspnoea
Inappropriate AffectDrug Withdrawal SyndromeSomnolence

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Suboxone
- support group for people who take Vyvanse

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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