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Review: Zoloft and Centrum

This review analyzes the effectiveness and drug interactions between Zoloft and Centrum. It is created by eHealthMe based on reports of 4,471 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Zoloft and Centrum >>>

What are the drugs

Zoloft (what 78,149 Zoloft users reported?) has active ingredients of sertraline hydrochloride. It is used in depression.

Centrum (what 9,053 Centrum users reported?) has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is used in vitamin supplementation.

On Aug, 16, 2014: 4,471 people who take Zoloft, Centrum are studied

Zoloft, Centrum outcomes

Drug combinations in study:
- Zoloft (sertraline hydrochloride)
- Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Zoloft is effective0.00%
(0 of 7 people)
(8 of 25 people)
(8 of 22 people)
(8 of 18 people)
(12 of 25 people)
(14 of 25 people)
(15 of 19 people)
(1 of 1 people)
Centrum is effective0.00%
(0 of 7 people)
(0 of 7 people)
(2 of 12 people)
(3 of 13 people)
(7 of 20 people)
(10 of 23 people)
(13 of 24 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
LethargyVentricular Septal DefectVentricular Septal DefectTransposition Of The Great VesselsPainAtrial Septal DefectShort-term Memory LossPain
HypoxiaAtrial Septal DefectRespiratory Tract InfectionDepressionDizzinessRespiratory DistressDepressionNausea
Drug Exposure During PregnancyPatent Ductus ArteriosusEar InfectionTricuspid Valve IncompetenceVaginal HaemorrhageFatiguePulmonary EmbolismFatigue
Confusional StateMajor DepressionCroup InfectiousAtrial Septal DefectAtrial Septal DefectPatent Ductus ArteriosusPenicilliosisAnxiety
NauseaDrug Exposure During PregnancyAnomalous Pulmonary Venous ConnectionPatent Ductus ArteriosusDepressionGait DisturbanceErythrosisDepression
AnxietyDouble Outlet Right VentriclePost Procedural ComplicationNeonatal Respiratory Distress SyndromeUterine SpasmVentricular Septal DefectSerotonin SyndromeAnaemia
Oxygen Saturation DecreasedInjuryDrug Exposure During PregnancyVentricular Septal DefectMaternal Exposure During PregnancySupraventricular TachycardiaExhaustion, Fatigue, Lethargy, Tiredness, WearinessDiarrhoea
Patent Ductus ArteriosusEmotional DistressOtitis MediaPneumothoraxNauseaPulmonary HypertensionMacular DegenerationWeight Decreased
Transposition Of The Great VesselsHypersexualityUpper Respiratory Tract InfectionCardiac Failure CongestiveCardiac MurmurCardiomegalyTendon InjuryHeadache
DyspnoeaTransposition Of The Great VesselsStrabismusCongenital Coronary Artery MalformationDrug Exposure During PregnancyAnxietyDizzinessDyspnoea

Drug effectiveness by gender :

Zoloft is effective50.48%
(53 of 105 people)
(13 of 37 people)
Centrum is effective37.33%
(28 of 75 people)
(7 of 31 people)

Most common drug interactions by gender * :

PainAtrial Septal Defect
AnaemiaOsteonecrosis Of Jaw
Weight DecreasedDiarrhoea

Drug effectiveness by age :

Zoloft is effectiven/an/a25.00%
(2 of 8 people)
(5 of 48 people)
(10 of 31 people)
(14 of 36 people)
(19 of 83 people)
(16 of 63 people)
Centrum is effectiven/an/a0.00%
(0 of 5 people)
(3 of 45 people)
(9 of 22 people)
(5 of 25 people)
(13 of 63 people)
(5 of 41 people)

Most common drug interactions by age * :

Patent Ductus ArteriosusFoetal Exposure During PregnancyPhotophobiaAnxietyPainDepressionPainFall
Atrial Septal DefectPyrexiaPainPainNauseaPainAnxietyNausea
Cardiac Failure CongestiveNasal CongestionDepressionNauseaFatigueFatigueNauseaPain
CardiomegalyCleft PalateHeadachePregnancyWeight DecreasedNauseaHeadacheAsthenia
Heart Disease CongenitalConductive DeafnessVomitingCholecystitis ChronicAstheniaAnxietyFatigueFatigue
Ventricular Septal DefectHaemangioma Of SkinDiarrhoeaDepressionConvulsionAnaemiaOsteonecrosis Of JawWeight Decreased
CryptorchismCleft LipDizzinessDeep Vein ThrombosisHeadacheBone DisorderBone DisorderDiarrhoea
Failure To ThriveCellulitisCondition AggravatedDrug Exposure During PregnancyDrug Exposure During PregnancyOsteonecrosis Of JawAnaemiaAnxiety
Maternal Exposure During PregnancyOtitis MediaSinus HeadacheConvulsionInjuryConstipationBack PainArthralgia
Croup InfectiousEar InfectionSuicidal IdeationHeadacheAnxietyArthralgiaDepressionDepression

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Zoloft and Centrum
- group for people who take Centrum
- group for people who take Zoloft

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  • From this study (11 months ago):

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More reviews for: Centrum, Zoloft

Complete drug side effects:

On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) is often used to treat general physical condition abnormal. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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