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Review: Abilify and Morphine





Summary: drug interactions are reported among people who take Abilify and Morphine together.

This review analyzes the effectiveness and drug interactions between Abilify and Morphine. It is created by eHealthMe based on reports of 243 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Abilify and Morphine >>>

What are the drugs

Abilify has active ingredients of aripiprazole. It is often used in depression. (latest outcomes from Abilify 30,166 users)

Morphine has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Morphine 49,746 users)

On Nov, 24, 2014: 243 people who take Abilify, Morphine are studied

Abilify, Morphine outcomes

Drug combinations in study:
- Abilify (aripiprazole)
- Morphine (morphine sulfate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Abilify is effective50.00%
(1 of 2 people)
n/a100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
n/a0.00%
(0 of 1 people)
n/an/a
Morphine is effective0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
n/a100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
GranulocytopeniaHaemoglobin DecreasedSudden Cardiac DeathSepsisDrug Ineffectiven/an/aPain
PancytopeniaDecreased AppetiteFatigueRhabdomyolysisDouble VisionAnxiety
Renal Failure AcutePyrexiaDehydrationDisorientationChest Pain
PyrexiaNeutropeniaDeathBack Pain
RashPneumoniaPain In Extremity
Haemoglobin DecreasedAgitationOsteonecrosis Of Jaw
InfectionNeutrophil Count DecreasedFall
Decreased AppetiteSepsisHypertension
ThrombocytopeniaAnxietySpinal Osteoarthritis
NeutropeniaInfectionDiabetes Mellitus

Drug effectiveness by gender :

FemaleMale
Abilify is effective25.00%
(1 of 4 people)
50.00%
(1 of 2 people)
Morphine is effective25.00%
(1 of 4 people)
50.00%
(1 of 2 people)

Most common drug interactions by gender * :

FemaleMale
PainChest Pain
AnxietyDiabetes Mellitus
HypertensionType 2 Diabetes Mellitus
Back PainAnxiety
Osteonecrosis Of JawMetastases To Bone
Pain In ExtremityFall
Urinary Tract InfectionPain
Chest PainDyspnoea
AnaemiaConfusional State
InsomniaNeoplasm Malignant

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Abilify is effectiven/an/an/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
0.00%
(0 of 1 people)
33.33%
(1 of 3 people)
Morphine is effectiven/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
0.00%
(0 of 1 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aDeathDrug Effect DecreasedAbdominal PainDiabetes MellitusPyrexiaFall
Cardio-respiratory ArrestMultiple SclerosisChest PainRectal HaemorrhageDecreased AppetitePain
UlcerMaternal Exposure During PregnancyAnxietyPulmonary EmbolismHaemoglobin DecreasedAnxiety
Pain In JawDepressionTooth AbscessType 2 Diabetes MellitusNeutropeniaBack Pain
Unresponsive To StimuliAsthmaDiarrhoeaHypotensionPlatelet Count DecreasedPain In Extremity
HeadacheCondition AggravatedPainEnterocolitis HaemorrhagicType 2 Diabetes MellitusOsteonecrosis Of Jaw
SnoringDrug IneffectiveConstipationMemory ImpairmentDiabetes MellitusOedema Peripheral
Pulmonary OedemaPancreatitisVomitingThrombocytopeniaPneumoniaChest Pain
Cardiac ArrestCholecystitis ChronicNauseaBlood Cholesterol IncreasedNauseaConfusional State
Respiratory ArrestFallConfusional StateDeep Vein ThrombosisPainDepression

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Abilify and Morphine?

You are not alone! Join a related mobile support group:
- support group for people who take Abilify and Morphine
- support group for people who take Abilify
- support group for people who take Morphine

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Is osteoarthrisis caused by drinking alcohol
    Chronic pain in spine, right hip, right hand, swollen joints in both hands, swollen knees.
  • Is vomiting all liquids common while taking morphine
    I Recently started taking 6mg of Hydro-Morphine per day for pain. Every time i take the drug i vomit up any liquids I drink. i fell just fine without anything in my stomach but as soon as i eat or drink I instantly become nauseated and vomit everything. It is hard not to drink because the drug is making me very thirsty. So i try to drink and my body rejects it over and over again.. this goes on for hours (3-5)because i am sooo thirsty that I can not stop drinking.
  • Is the pancreatic malfunction caused by abilify irreversible or stopping the drug can restore normal levels of sugar in the blood
    I want to know if stopping the use of Abilify will restore the normal functioning of the Pancreas. Reducing the dosage would reduce the levels of sugar in the blood.
  • Can mrsa cause chronic intestinal pseudo obstruction?
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
    I never really recovered... The obstruction returned after 2 days and a portion of necrotic bowel was removed, then further fever and cellulitis then MRSA and deaths door.... Isolation in high dependency (intensive care) wound break down, ventilated and all related issues that come with that - chest infection, pneumonia, bed sores. Total time in hospital 8 months. Negative pressure dressing on laparotomy wound, colostomy, picc, 4 rounds of vancomycin, minor flirt with heart failure (just water related) an eventually everything healed. Had a large incisional hernia to repair and some corrective work to the horrific scarring but then the neuropathy started plus problems eating, spewing up after any solid food, more than a few forks, diarrhoea and sickness or constipation nausea and pain driving me mad, tried all manner of drugs, nerve blocks, physio, floating tank, acupuncture, opiates, non opiates, spinal cord stimulation, an now a consultant just had a 'eureka' moment and said were you treated with vancomycin when you had MRSA? If so I'm pretty sure you have chronic intestinal pseudo obstruction and is 90% sure but wants to take a muscle biopsy to be certain. I've had so much surgery and bad news in the last 10yrs I'm terrified of germs, hospital acquired bugs and anaesthetics, is there any other way? Or can I have this test done awake - conscious sedation? I had it before during spinal cord surgery so I know what's involved and it's better than GA as I know what's going on, who is doing what to me etc...
    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
  • Why would i get copd since i never smoked?
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life.
    My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.

More questions for: Abilify, Morphine

You may be interested at these reviews (Write a review):

  • I take abilify and i have hemerroids
    I take Abilify and all the side effects so fare are posted above
  • Prostatitis and prostate cancer acceleration due to anaesthetics
    Caught Chlamydia in 1978. Interestingly, the partnered girl's sister worked in an aviary; and I found out later that Chlamydia originates from handling birdshit and birds are the carriers. Chlamydia was undiagnosed at the time, so it was listed under 'Non-specific urethritis'. Chlamydia wasn't named until about 8 years later. I was given tetracycline and told to stay off alcohol and sex. Yeah, really?

    I was 24; highly sexed, and in night clubs and pubs most nights. I laid off the alcohol and after two weeks, I was good. The laying off sex, I understood, because of contamination of others (condoms were little used in 1978 in the singles arena); so I masturbated one night... and that caused me immense in my prostate, and pain and suffering for the rest of my life.

    The ejaculation was extremely painful, and chronic prostatitis started. I was on and off medication for two years. I got light-sensitivity, which means in sunlight, I came out in burning rashes. I became allergic to tetracycline.

    The message? Consultants are generally poor at communicating what not to do, and why not. Lay off sex he said. All he had to say was no sex, no masturbation; or you may suffer for the rest of your life. That would have done it.

    No-one has been able to help me with this chronic prostatitis. In the early years it would come and go, but as the years have gone on, it has become more frequent, and now it is constant.

    Four years ago I went in for major foot surgery, and flat-lined. I was in intensive care for 2 days, on a morphine drip for the pain.
    When I awoke, I knew immediately I was suffering with my prostate. It was aching badly and I was urinating frequently. The nurses were amazed with how many 'bottles' I filled in such a short time.
    For the next few months, I was in agony. I have tried every possible drug going, as well as prostate massage and the indignancy of a urethragram whilst female students were watching.

    In November 2011 I went to see another consultant, who suggested a biopsy. I was diagnosed with prostate cancer. After much research, I now know that my diet and lifestyle, coupled with inflammation of the prostate with prostatitis, has caused prostate cancer. Yes, there is a direct relationship between prostatitis and prostate cancer.

    I am now beating it, without drugs and without surgery. I have changed my diet to a vegan diet, no sugar, very little alcohol, and a lot of supplementation.

    In December 2013, I went in for more foot surgery. I was unaware about the morphine at this time, so didn't consider it being a problem. I talk to the anaesthetist, who wanted me to have an epidural (injection in the spine to numb my lower body). At no point did he talk to me about my prostate history.
    In recovery, I sensed a problem as soon as the anaesthetic began to wear off. It was like my prostate and testicles wanted to explode. I knew I was going to have problems. My intuition reminded me of three years ago with the morphine, so I asked the surgeon if he knew of these complications with morphine, but he didn't.

    I spoke to the head of the post-operative ward and asked her if she had any experience of post-operative patients who suffered with prostatitis after surgery, and she confirmed she had. So here was a nurse who knew of the problems, but the surgeon and anaesthetist didn't. This is typical in the health service... the lack of sharing.

    Not only did I suffer with the chronic prostatitis (and still am 11 month later) I was incontinent. It took 6 months of 4-times daily legal exercises to get back control of my bladder.
    For me, morphine has a dire effect on my prostate.

    Bear in mind that your prostate is designed to eliminate toxins, so it is flooded with morphine. I will do my best to ensure I check for morphine in any drugs or anaesthetics in future.

    My first PSA level was 18, 3 ears ago. I brought it down to 13.5, then 10.4, 10.3, 10.9, 11.3, 14.3 and after the last surgery it spiked at 17.5. As a result, I have gone back to a stricter, greener raw diet to bring it down again.

    Oh, and anther tip; you need to get your vitamin D3 blood count above 200n/mols (UK measure) to have any chance of not getting prostate cancer. Mine was 32 when I was diagnosed. Today it is over 200, from supplementation of 10000 ius a day. Minimum in the UK, recommended by scientists, is 75n/mols, and it's too low. OK if you have a great immune system, but not if you want to fight prostate cancer and prostatitis.

    Black African males in the Northern US states and in Europe have twice as much risk, due to lack of sunlight. Sunlight on skin promotes vitamin D3, which is essential for the immune system and production of calcium.

    Black African males need more sunlight to produce the same amount of vitamin D3 as a caucasian male. Also, any male who is bald and fat has a higher risk, so a Black African, obese bald male, has an extremely high risk of prostate cancer, unless they get their immune system in order.

    The main way to fight all this, is on a clean, raw vegetable diet, pure water, no alcohol, sugar, processed or refined food, no meat, no dairy, no vegetable oil, no exceptions, and some breath-taking regular exercise. Just like we did 100 years ago. Go figure! Look at chronic disease studies of 100 years ago. 85% of all disease was from infection. Today 85% is from chronic disease.

    Your prostate eliminates toxins, and today, we are overloading it. Remove the toxins (and the stress and anxiety) and things will improve. It's a hard road; but with it is you want to be healthier and live longer.

    Good luck.
    Glenn.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Androgel for secondary hypogonadism
    Severe swelling in legs, ankles and feet after being on my feet for more than one hour. Pain in calves and ankles. Feels like they're being squeezed or compressed. Pain dissipates after laying down for a few hours. Swelling never completely dissipates. Always some swelling in ankles.
  • Bpd and insomnia with abilify and cymbalta
    I am currently in recovery from BPD, but still have some traits. I also suffer from depression. I suffer with insomnia also. I have noticed that if I forget to take my meds, I have a higher chance of not sleeping that night.

More reviews for: Abilify, Morphine

Comments from related studies:

  • From this study (3 months ago):

  • I started taking bupropion for depression 6 mos ago. A month ago I added paroxetine. About 2 wks ago I started Abilify at 1 mg/day. Several days after starting Abilify I developed diplopia so severe I could hardly drive. I stopped the Abilify 6 days ago and the diplopia and disorientation has improved substantially. Slight to moderate handshaking is still occurring. Slight hand shaking was present before I started paroxetine and Abilify. I have suffered from pain in the knee for 14 yrs. I also suffered from testosterone deficiency for 7-8 yrs and have been on testosterone for 3-4 yrs.

    Reply

  • From this study (3 years ago):

  • I am suddenly feeling very sore joint pain, especially in the shoulders and fingers. This started once I added the morphine and the lyrica. I find the pain is almost as strong as my back pain.

    Reply

    2tired2beme on May, 22, 2012:

    50yr, Female, WA State
    I checked myself in-patient because I was at my wits end, feeling hopeless and isolating myself. The docs immediatesly loaded me up with Abilify, Lamictal, Zyprexa, Seroquel, Alprazolam, Ambien, and God knows what all else! I didn't take them long as my copays were $60ea for most of them.

    Months after quitting most of them, I was having severe pain at the base of my skull, radiating deep into my bone marrow and shoulders and upper back/neck. My jaw also developed a horrible forward thrust and sideways shift. The more stressed I get, the more exagerated my jaw contorts. My face hurts all the time.
    The muscles in my neck shrug and my head sinks downward into my neck, straining forward. It is esp. worse when I drive!
    I never related my skull/neck/shoulder pain and my jaw thrusting with the Abilify or Lamictal up until an acquaintance pointed it out on one of their commercials.
    I have been taking 2mg of sublingual Suboxone twice daily for a couple years and my neck pain entirely diminished. It took 5-6weeks to get used to the dopey effects from the suboxone, but I don't feel a thing from it anymore.
    The only downfall is that Suboxone is an Opiate inhibitor so pain prescription meds won't, the opiate effect is blocked. If you have surgery, you need to discontinue the Suboxone 36hrs before hand and not take them until you are certain you will no longer need any pain meds. The withdrawl period for Suboxone is yukky but only lasts a couple days. Apparently, suboxone is mainly prescribed for meth and opiate addicts to withdrawl from their opiates, SO if you find a doctor who is willing to let you try Suboxone, he/she MUST write on the script that it is being rx'd FOR PAIN. Otherwise, the doctor has to have some type of special credentials for treating addicts. ANY M.D. can write a script for Suboxone as long as he writes: For Pain ON THE SCRIPT.

    Reply

Complete drug side effects:

On eHealthMe, Abilify (aripiprazole) is often used to treat depression. Morphine (morphine sulfate) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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