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Review: taking Acetaminophen and Methadone together

Summary: drug interactions are reported among people who take Acetaminophen and Methadone together.

This review analyzes the effectiveness and drug interactions between Acetaminophen and Methadone. It is created by eHealthMe based on reports of 921 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Acetaminophen and Methadone >>>

What are the drugs

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from 70,716 Acetaminophen users)

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,848 Methadone hydrochloride users)

On Feb, 3, 2015: 921 people who take Acetaminophen, Methadone Hydrochloride are studied

Acetaminophen, Methadone Hydrochloride outcomes

Drug combinations in study:
- Acetaminophen (acetaminophen)
- Methadone Hydrochloride (methadone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Acetaminophen is effective100.00%
(1 of 1 people)
n/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/an/a
Methadone Hydrochloride is effective100.00%
(1 of 1 people)
n/an/an/a0.00%
(0 of 3 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DehydrationColostomyPainLower Respiratory Tract InfectionSubarachnoid HaemorrhageConfusional StateTorsade De PointesNausea
HyperglycaemiaHospitalisationDyspnoeaUlcer Haemorrhage NosFallWeight IncreasedLong Qt SyndromePain
Palmar-plantar Erythrodysaesthesia SyndromeColitis UlcerativeCentral Nervous System LesionShockSyncopeRegurgitationAnxiety
Oedema PeripheralIleusElectrocardiogram AbnormalMelaenaVentricular TachycardiaIncreased AppetiteDyspnoea
FatiguePainNauseaAnaemiaSerotonin SyndromeAbdominal DiscomfortConstipation
HyperhidrosisLoss Of ConsciousnessChest DiscomfortRectal HaemorrhageFacial Bones FractureEructationAsthenia
HypoalbuminaemiaHyperhidrosisBlood Creatinine IncreasedOesophageal ErosionsElectrocardiogram Qt ProlongedStomach PainFatigue
AnorexiaIleus ParalyticCalculus UrinaryCirculatory CollapsePainVomiting
Neutrophil Count DecreasedApnoeaLethargyGrand Mal ConvulsionSweating - ExcessiveBack Pain
Haemoglobin DecreasedPupillary Reflex ImpairedVision BlurredHaematemesisStomach PainDepression

Drug effectiveness by gender :

FemaleMale
Acetaminophen is effective100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
Methadone Hydrochloride is effective50.00%
(1 of 2 people)
0.00%
(0 of 2 people)

Most common drug interactions by gender * :

FemaleMale
NauseaFatigue
PainAsthenia
AnxietyAnxiety
DyspnoeaConstipation
ConstipationDyspnoea
HeadacheDepression
Osteonecrosis Of JawNausea
Back PainDizziness
VomitingAnaemia
Abdominal PainPain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Acetaminophen is effectiven/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 3 people)
n/an/a0.00%
(0 of 1 people)
Methadone Hydrochloride is effectiven/an/an/a50.00%
(1 of 2 people)
0.00%
(0 of 3 people)
n/an/a0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
HypertensionViral Infection NosEpistaxisNauseaNauseaBack PainAnxietyNausea
Hypoplastic Left Heart SyndromeFebrile NeutropeniaPyrexiaRespiratory DepressionDyspnoeaConstipationPainVomiting
Hepatic FailureAnorexiaFatiguePulmonary OedemaHeadacheDyspnoeaOsteonecrosis Of JawChest Pain
HypotensionBone PainHypokalaemiaAccidental OverdoseAnxietyDizzinessNauseaDyspnoea
Organ FailureAbdominal Pain NosCaecitisOverdoseAccidental OverdoseNauseaEmotional DistressCompleted Suicide
DyspnoeaDiarrhoea NosMuscle SpasmsCardio-respiratory ArrestFatigueAstheniaDepressionDehydration
ArrhythmiaDisease Progression NosPhotophobiaHepatitis CVision BlurredFatigueAbdominal PainAsthenia
UrticariaNeck PainLower Respiratory Tract Infection FungalVomitingPainVomitingArthralgiaConfusional State
SepsisRespiratory DistressThrombocytopeniaMultiple Drug OverdoseDehydrationWeight DecreasedConstipationHyperhidrosis
Renal InjuryPleural EffusionPruritusMyocardial IschaemiaPalmar-plantar Erythrodysaesthesia SyndromeHeadacheDyspnoeaPain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Acetaminophen and Methadone?

You are not alone! Join a related mobile support group:
- support group for people who take Acetaminophen and Methadone
- support group for people who take Acetaminophen
- support group for people who take Methadone Hydrochloride

Can you answer these questions (Ask a question):

  • Why is restoril showing poaitive in my urin when i never took this drug (2 answers)
    I have been ill for 15 years, taking Methadone all the while along with Soma and Hydrocodone for break thru pain. I now include Lyrica daily.I have had 2 back surgeries, one detailing rod and cage around L4 L5 in 2007. Most recent Nov 2013 at the Laser Spine Institute for spine decompression in that same area. Diagnosed w/ Arachnoiditis 15 yrs ago when working full time and since Methadone seems to be my only safe bet to take so that I can function. 4 years on Hizentra IVG home treatment every week. Lorazapam was prescribed for panic. Tried Diazapam more than 8-9 months ago, however that drug seems to back up in my system therefore I get no immediate relief but sort of a knock out sleep 8 hours later so we went back to Lorazapam. I am now unfortunately disabled, mostly homebound and 60 yrs old. Since this past August my urin specimen has come back positive for Restoril. This past month Restoril is still positive and described as habitual use. I am staring down a discharge from my physician who I care for, respect and admire, I never ever thought this would happen. We just took another test I offered to get another different Lab test she told me to wait so I am but its killing me. I never took a sleeping other than Unisom OTC in my Entire life. Never been prescribed Restoril, no offense but would never take it on top of what I already take and Lord knows how I would react to this drug. If I am awake all night that's just the way it is and I live with it. Why is this foreign drug showing up in my system? Please help. Thank you kindly, Louise
  • What are the side effects of taking methadone and cefdinir
    I know there are some antibiotics that do not go well with methadone. I need to know if anyone has ever had these two together and how well it worked or not
  • Will a hiatal hernia swell or decrease or stay the same size?
    After taking Tylenol, my hiatal hernia is tender to the touch and seems to get bigger and protrudes more. Is this happening or do I just imagine it seems bigger?
  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Can i take ketorolac if i am already taking methadone everyday?
    I take methadone everyday and I have a tooth ache so can I take ketorolac with methadone?

More questions for: Acetaminophen, Methadone Hydrochloride

You may be interested at these reviews (Write a review):

  • The dangers off fluoridation
    I live in an area where the water has been fluoridated for approximately 55 years and have been treated for an underactive thyroid since 1978. I have also suffered from urge incontinence since 1967 and for 4 years have also had the symptoms of skeletal fluorosis although I have not been able to get the tests to confirm this. About 2 years ago I read about the dangers of fluoride and stopped using the tap water for drinking and cooking but still had to use it for bathing and still swam in the local pool. Also I have always drunk about 3 pints of tea a day. Recently it was found that there might be a problem with my kidneys so I stopped drinking tea and swimming. I had been going to the toilet 16/17 times a day but after about 5 weeks this was down to 7/8 times and the urgency was gone. Also I was given a follow up kidney function test after 6 weeks and that was normal. A few weeks later I was shopping in an area where the water is not fluoridated and risked having tea in a cafe there and the irritable bladder symptoms came back almost immediately and lasted for several weeks.
  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Methadone and forgetting basic things.
    I have been in MMT (Methadone Maintenance Treatment) for around 7 1/2 years for chronic pain. I have gotten to where I forget things that I never would or did before and the longer in time the worse it has gotten I am currently looking at some different meds for treatment. The loss of memory is everything from childhood memories to what I did yesterday I may pay something and if I dont write it diwn I will forget it things I have known all my life I have forgotten. I can't say 100% it is from the MMT or not however I will sag I had no such problems before and I am at age 38 so I believe I am much too young to have severe memory loss that I am currently experiencing and whats scary is what if it never comes back and continues to decline?
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.

More reviews for: Acetaminophen, Methadone Hydrochloride

Comments from related studies:

  • From this study (1 year ago):

  • Decreased fetal movement

    Reply

  • From this study (5 years ago):

  • It seemed that the otc meds may have caused the methadone to wear off very quickly or rush out of my system causing what feels like withdrawal symptoms

    Reply

Complete drug side effects:

On eHealthMe, Acetaminophen (acetaminophen) is often used to treat pain. Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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