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Review: taking Adderall and Topamax together

Summary: drug interactions are reported among people who take Adderall and Topamax together.

This review analyzes the effectiveness and drug interactions between Adderall and Topamax. It is created by eHealthMe based on reports of 422 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from 16,963 Adderall users)

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from 24,610 Topamax users)

On Mar, 3, 2015: 422 people who take Adderall, Topamax are studied

Adderall, Topamax outcomes

Drug combinations in study:
- Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)
- Topamax (topiramate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Adderall is effective10.00%
(1 of 10 people)
33.33%
(8 of 24 people)
42.86%
(6 of 14 people)
64.52%
(20 of 31 people)
58.62%
(17 of 29 people)
68.42%
(13 of 19 people)
83.33%
(5 of 6 people)
50.00%
(3 of 6 people)
Topamax is effective16.67%
(1 of 6 people)
21.05%
(4 of 19 people)
7.69%
(1 of 13 people)
35.71%
(10 of 28 people)
46.43%
(13 of 28 people)
61.90%
(13 of 21 people)
81.82%
(9 of 11 people)
0.00%
(0 of 6 people)

Drug effectiveness by gender :

FemaleMale
Adderall is effective51.56%
(66 of 128 people)
50.00%
(4 of 8 people)
Topamax is effective40.00%
(50 of 125 people)
14.29%
(1 of 7 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Adderall is effectiven/a0.00%
(0 of 1 people)
15.38%
(2 of 13 people)
42.00%
(21 of 50 people)
25.00%
(24 of 96 people)
22.97%
(17 of 74 people)
42.86%
(6 of 14 people)
0.00%
(0 of 4 people)
Topamax is effectiven/a0.00%
(0 of 1 people)
25.00%
(3 of 12 people)
24.49%
(12 of 49 people)
12.64%
(11 of 87 people)
27.63%
(21 of 76 people)
21.43%
(3 of 14 people)
25.00%
(1 of 4 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
InsomniaDizzinessMood SwingsHeadacheDepressionInsomniaDizzinessFatigue
Suicidal IdeationChest PainInitial InsomniaInsomniaExhaustion, Fatigue, Lethargy, Tiredness, WearinessHyperhidrosisHeadachePain
Dry MouthDissociative FugueUrge IncontinenceDizzinessNeck PainDepressionVision BlurredDepression
Weight DecreasedDepressionLethargySneezingDizzinessLoss Of EmploymentNight SweatsHeadache
DizzinessDisturbance In AttentionDepression NosNauseaIrritabilityHot FlushesItchingDrug Ineffective
Heart Rate IncreasedEye PainSputum Expectoration DifficultExhaustion, Fatigue, Lethargy, Tiredness, WearinessNauseaUrinary Tract InfectionSeborrhoeic DermatitisNausea
DepressionDehydrationThroat TightnessUrinary Tract InfectionHeadacheThoughts - CloudyFatigueWeight Increased
HeadacheHallucinationAir SwallowingUti - RecurrentDry MouthWeight IncreasedAbdominal PainTremor
HallucinationBipolar I DisorderIrritabilityHivesTeeth ClinchingCoordination ImpairmentMood ChangesChest Pain
Impaired Work AbilityMenorrhagiaBlood Pressure IncreasedLightheadednessDeafness UnilateralSleep AttacksIrritabilityOedema Peripheral

Most common drug interactions by gender * :

FemaleMale
FatigueDiarrhoea
HeadacheDehydration
PainHaemorrhoidal Haemorrhage
NauseaGastritis Erosive
DepressionPneumonia
Oedema PeripheralHypovolaemia
Chest PainColitis
DizzinessTremor
Drug IneffectivePulmonary Embolism
Weight IncreasedDepression

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Musculoskeletal StiffnessTicType 1 Diabetes MellitusFatigueNauseaPainAstheniaLimb Crushing Injury
TremorAttention Deficit/hyperactivity DisorderObesityPsychotic DisorderDepressionFatigueAnxietyNeuralgia
HypersensitivityEmotional DisorderDiabetes MellitusGranulocytopeniaDyspnoeaDehydrationTremorOedema Peripheral
Heart Rate IncreasedWeight DecreasedDiabetic KetoacidosisFeeling AbnormalHeadacheHeadacheSomnolenceJoint Swelling
FatigueSweating DecreasedAnxietyAggressionPneumoniaDepressionDizzinessJaw Fracture
HeadacheGastroenteritis NosHyperglycaemiaInsomniaMigraineDiarrhoeaDyspnoeaHip Fracture
DyspnoeaIntracranial Pressure Increased NosTremorSuicide AttemptChest PainOedema PeripheralFallHypertonic Bladder
Musculoskeletal DisorderGlycosuriaAstheniaSinusitisVomitingSpeech DisorderPain In Extremity
Haemorrhage NosDepressionSneezingFatiguePulmonary EmbolismMental Status ChangesPelvic Fracture
Disturbance In AttentionImpulsive BehaviourJoint InjuryChest DiscomfortMultiple Sclerosis RelapseMigraineTransient Ischaemic Attack

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Adderall and Topamax?

You are not alone! Join a related mobile support group:
- support group for people who take Adderall and Topamax
- support group for people who take Adderall
- support group for people who take Topamax

Can you answer these questions (Ask a question):

  • Can hemorrhoids me caused by taking adderall?
    I've had the Hemorrhoid banding done, it didn't work. I've used Proctozone-HC 2.5% hasn't worked.
  • Cannabidiol interact topiramate
    Chronic Migraines, taking Topomax & propanidol with mild success. Are there any major interactions with cannabidiol (CBD)and the drugs I'm taking?
  • Can daliresp cause sever lower back pain and light perioud bleeding?
    I started Daliresp tab.and i began having a really bad rash in my private parts .. by the 3rd day i started having awful pain in my lower back with some light blood in my urin, now i have this severe pain and its as if i have a light perioud. i had a comple hysterectomy in 2003,due to overian cancer. i will call my pulmonaligist who put me on this medication on monday the 26th . but i am concern thats why i am asking ...
  • Is it possible to suddenly form ulcers after 20 years of tegretol usage
    have been using tegretol and Topamax for over 20 years and only now starting to get severe mouth ulcers
  • Does adderal have an effect on alzheimers? (1 answer)
    Adderall has been effective in treatment of ADHD, and I like it. It is highly effective as treatment of lack of focus, and I find that tasks (such as academic research) are much enhanced by it. However I am beginning to experience what I fear is early stages of Alzheimer's.(I am 68). I have been studying the disease, and have been doing things recommended as valuable to retard Alzheimer's development as well as to counter symptoms such as forgetfulness, and loss of mental acuity with significant success. I believe, at least in the short run, Adderall has had a positive effect in my endeavors to counter the symptoms of the disease. However, since one of the principal causes of Alzheimer's is inflammation, I wonder if Adderall causes inflammation, and if it does, is there a way to counter the inflammation?

More questions for: Adderall, Topamax

You may be interested at these reviews (Write a review):

  • Best drug ever invented for add
    1 XR 30mg capsule in the morning and 3x10's throughout the day and I am able to act as a competent lawyer, learn any kind of task, skill, focus and finish tasks until completed. Without the XR30 in the morning, I am more likely to be irritable with those around me; I wouldn't have the typical 2-3 second "delay before speaking" that most non-medicated folks have; and I would start many projects but be unable to finish any. I have been taking Adderal for over 20 years, never developed a tic or rapid heart beat, any kind of "warned symptoms," and have to say that this is unquestioningly the best drug for adult ADD ever invented. I find that I have the ability to learn math or electrical science etc., you name it. I am so grateful to have discovered it at age 30.
  • Toperimate has ruined my life!
    On Dec 2, 2015 I started taking Toperimate for severe back pain. Within 48 -36 hours I became very sick - throwing up, nausea, blood in my feces, putrid taste in mouth, blurry eyes, difficulty sleeping, confusion and severe fatigue. I felt like I was poisoning myself! After 7 days I felt no improvement to my back pain and was in pretty bad shape. So I made the decision to go off of it after day 7's dose. On day 9, I woke up with severe VERTIGO. I thought I was dying, it was so bad! Was it a brain tumor (I wondered at the time, horrified!)? I didn't know. I believe (actually I KNOW) it was a side effect of the Toperimate, which can cause vertigo. I also immediately began to feel drunk all the time, even when I wasn't "spinning". I had vertigo and the drunk feeling for 1week and then I went to Urgent Care. The doctor was useless and only gave me Valium. No answers, no improvement. I waited 3 more weeks, desperate, and again went to second UC doctor. This one was competent. He diagnosed me with BVVP ( Benign Paroxysmal Positional Vertigo - which us caused by dislodged calcium crystals in my inner ear.) and set me up to have the Epley Manuever through Vestibular Rehab Physical Therapy. My vertigo was (temporarily) corrected after the first PT visit. Although I was thrilled, I was STILL feeling drunk. I've had both an MRI and MRA to rule out brain rumors, etc. everything, thank God, came out clean. Yes! But I still felt drunk 24/7. 3 weeks after The Physical Therapist corrected my vertigo. It fully came back. I was devastated! But I was able to correct it myself by doing the Epley Maneuver by myself at home. I watched a Youtube Video for instructions. I need to mention that I believe I caused the vertigo to return the second time because the night before it returned, my husband used a vibrating massager on the back of my head/upper neck area because I had pain there. I learned from my PT that the vibrations could have again dislodged the calcium crystals in my inner ear. Strange, right? She said often the PTs use vibration to force the crystals back where they're supposed to be. Apparent, the opposite is true too. Well, today is February 2, 2015. I haven't had a recurrence of my vertigo but I STILL FEEL DRUNK 24/7!!!! Thanks Toperimate and it's makers, and the doctor that gave it to me. It was supposedly a "conservative approach" to my back pain, but the question is......will I ever feel normal again? If I do heal from this, I will try to remember to update this webpage again. Good luck to anyone who experiences this problem.
  • Belviq (lorcaserin) and adderall (amphetamine and dextroamphetamine)
    I have been on Adderall for more than a year and I have recently started taking Belviq. For some reason a lot of doctors worry about a serious interaction between the two, in my experience the two get along just fine. Adderall helps me stay focused, while Belviq suppresses appetite.
    During the second week of Belviq I did have very small stomach upsets, such as heartburn but it did go away about 2 days later. Other than that the medication works well and I think it is safe for anyone to try who is looking to lose weight. Belviq works on serotonin and while the exact mechanism is unknown it causes appetite suppression in most people. Belviq being one of the medications that are approved for long term use, it may be very helpful to individuals who require a longer period of time on the medication. Belviq reminds me of an antidepressant I was on called Effexor, the two produce the same sense of satisfaction overall, but mostly with food. However Effexor’s side effects (show up around week 7-12) and made it so that the medication is almost impossible to used. Belviq at this time is not giving me any side effects, I think it’s a wonderful drug, much better than the other options like Contrive and Qsyimia. However it’s not for everyone the drug may work perfectly on 80 % of the people who try it but on others it may not. I recommend that the alternatives be considered such as Contrive or Qsymia if Belviq is not found helpful. If Belviq causes you to feel unwell, sad, depressed, or feel like you have the flu—stop taking Belviq and call your doctor as these may be signs of a life threatening condition. Always take the medication as directed by your doctor, do not adjust your own dose without consulting with the doctor.
    Belviq has been a wonderful addition to my life, it’s helped me take control of my body again I feel that the medication is very good, well tolerated, and just an amazingly well designed drug overall.
  • Urea urine increased while taking topamax
    I was on Topamax to lose weight. It worked for me, I lost weight but my blood urea increased. I have to stop taking it.
  • Massive aggression within first 4 days at 50mg (1 response)
    am only taking 50mg and have only been taking it for 4 days(this is the evening of the 4th day)as a preventative for migraine headaches that I have suffered from from 16 years. I have had pins and needles in my hands and feet as well as spontaneous crying fits since day 2 and Major aggression since yesterday. With normally an insurmountable amount of patience with my 1 year old son, I outright yelled at him last night. This is unacceptable. I have never felt such quick and sudden rage over nothing before, well, over anything before.

More reviews for: Adderall, Topamax

Comments from related studies:

  • From this study (4 months ago):

  • Edema of ankles and lower legs, blister-like or pimple-looking rash on face and inside throat. Hyper sensitive to light touch. Insomnia, manic-like desire to stay awake.

    Reply

  • From this study (5 months ago):

  • Had many episodes. This one is going on and on with many treatments including shampoos steroids injections and steroid lotions and steroid shampoos and it is still horrible. These episodes seems to keep happening more and more and taking over my life. I also have fibromyalgia.

    Reply

  • From this study (9 months ago):

  • I have stopped taking Topramax for over 30 days, but remain on the Adderall.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) is often used to treat attention deficit hyperactivity disorder. Topamax (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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