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Review: Adderall and Trazodone





Summary: drug interactions are reported among people who take Adderall and Trazodone together.

This review analyzes the effectiveness and drug interactions between Adderall and Trazodone. It is created by eHealthMe based on reports of 546 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Adderall and Trazodone >>>

What are the drugs

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Adderall 16,855 users)

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from Trazodone hydrochloride 6,611 users)

On Dec, 13, 2014: 546 people who take Adderall, Trazodone Hydrochloride are studied

Adderall, Trazodone Hydrochloride outcomes

Drug combinations in study:
- Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)
- Trazodone Hydrochloride (trazodone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Adderall is effective27.27%
(3 of 11 people)
57.14%
(20 of 35 people)
66.67%
(16 of 24 people)
76.19%
(16 of 21 people)
43.33%
(13 of 30 people)
69.23%
(9 of 13 people)
84.62%
(11 of 13 people)
100.00%
(2 of 2 people)
Trazodone Hydrochloride is effective10.53%
(2 of 19 people)
48.28%
(14 of 29 people)
44.44%
(12 of 27 people)
60.00%
(18 of 30 people)
47.83%
(11 of 23 people)
76.92%
(10 of 13 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Muscle SprainPainAnxietyChest PainDyspnoeaDepressionDiabetic RetinopathyDepression
HeadacheCholelithiasisSleepinessAnxietyChest PainAnxietyDiabetes Mellitus Inadequate ControlAnxiety
ChillsInjuryPulmonary FibrosisPainPainMood SwingsBlood Glucose IncreasedPain
AlopeciaCholecystitisDyspnoeaHypersomniaAnxietyHeadachesProteinuriaChest Pain
Neck PainSweating IncreasedPresyncopeExhaustion, Fatigue, Lethargy, Tiredness, WearinessNight SweatsLipoatrophyWeight IncreasedSomnolence
WeaknessExhaustion, Fatigue, Lethargy, Tiredness, WearinessChest PainPulmonary EmbolismSweating IncreasedTolerance DecreasedRenal DisorderNausea
SleepinessShort-term Memory LossNon-cardiac Chest PainPain In ExtremityPain - ShoulderDizzinessDiabetic NeuropathyTremor
SedationDizzinessPainDepressionPain In ExtremityAppetite DecreasedDiabetic Eye DiseaseDyspnoea
InsomniaBlood Creatine Phosphokinase Mm IncreasedGeneral Physical Health DeteriorationDeep Vein ThrombosisNauseaNightmareRenal CystInsomnia
DiarrhoeaMemory LossChest DiscomfortNauseaDeep Vein ThrombosisSuicidal IdeationCoughGait Disturbance

Drug effectiveness by gender :

FemaleMale
Adderall is effective60.36%
(67 of 111 people)
62.16%
(23 of 37 people)
Trazodone Hydrochloride is effective50.46%
(55 of 109 people)
39.47%
(15 of 38 people)

Most common drug interactions by gender * :

FemaleMale
DepressionAggression
AnxietyDepression
PainAgitation
Chest PainConvulsion
NauseaAnxiety
Gait DisturbanceInsomnia
FallTremor
SomnolenceWeight Increased
DyspnoeaFatigue
InjuryDrug Withdrawal Syndrome

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Adderall is effectiven/an/a70.00%
(7 of 10 people)
31.68%
(32 of 101 people)
39.34%
(24 of 61 people)
24.59%
(15 of 61 people)
33.33%
(10 of 30 people)
33.33%
(2 of 6 people)
Trazodone Hydrochloride is effectiven/an/a44.44%
(4 of 9 people)
15.31%
(15 of 98 people)
38.60%
(22 of 57 people)
20.97%
(13 of 62 people)
43.33%
(13 of 30 people)
50.00%
(3 of 6 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
AggressionScreamingAggressionInsomniaPainMultiple Sclerosis RelapseAnxietyCondition Aggravated
ConvulsionIntentional Self-injuryDepressionAnxietyVomitingDyspnoeaSomnolenceDepression
Tardive DyskinesiaStaringSomnolenceSubstance AbuseWeight IncreasedLeukocytosisOedema PeripheralHallucination, Visual
AgitationWeight IncreasedConvulsionDrug ToxicityDiabetes Mellitus Inadequate ControlMuscle SpasticityFallDiabetic Neuropathy
Foaming At MouthAggressionType 1 Diabetes MellitusPolysubstance DependencePain In ExtremitySynovial CystDepressionHyperkinesia
Homicidal IdeationHepatic SteatosisHeadacheGallbladder DisorderImmune Reconstitution SyndromeChest PainFall
Suicidal BehaviourDiabetic KetoacidosisDepressionInjurySensory DisturbanceNauseaLiver Disorder
Bipolar DisorderPainNauseaBlood Glucose IncreasedArthritisInsomniaDissociative Fugue
AgitationDyspnoeaBipolar DisorderDiabetic RetinopathyProgressive Multifocal LeukoencephalopathyPainWithdrawal Syndrome
BiteTardive DyskinesiaParanoiaDepressionGait DisturbanceDyspnoeaTremor

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Adderall and Trazodone?

You are not alone! Join a related mobile support group:
- support group for people who take Adderall and Trazodone
- support group for people who take Adderall
- support group for people who take Trazodone Hydrochloride

Can you answer these questions (Ask a question):

  • Can i take garcinia cambogia while taking adderall, lithium, latuda
    I would like to start taking Garcinia Cambogia diet supplement colon cleansing regimen but I don't know if I can on these medications or not. Please help?
  • I'm starting 7.5 mg remeron tonight , how can i expect to feal in the morning? (1 answer)
    Long period of depression desperate to find something that will work quik and give me some energy.
  • Migraine, simple partial seizure, or something else?
    In the spring, I experienced a very strange "aura" type thing and I don't know what it was or what was causing it.
    It started with just me feeling a bit off which happens because I take Adderall, and I'm pretty sure I took it that day, I do experience some side effects, so just an anecdote I guess. I curled up with a blanket as I was starting to feel a bit more odd. I could hear voices coming from the TV in the other room but they didn't make any sense. Lights started to seem bright/blurry, and that's when I saw a black blob resembling my cat (he's black) sitting at my feet in my peripheral. When I looked down, it disappeared. The aphasia went away but I started to get a little freaked out because well there was no cat. This is when the headache started. Out of sorts, I got up still wrapped in my blanket and went to get ready for bed so I could sleep off whatever this weird thing was. As I walked upstairs I began to feel a bit more like I was in a dream or not quite fully in reality. Once I got upstairs I noticed repetitive flashing lights in a dark room which was quite startling so I ran into my room. I distinctly remember looking into my closet and seeing the shelves bulge out and feeling like my room was bigger than usual. I quickly got changed and went to the bathroom to brush my teeth and such, more flashing lights, and the real lights in the bathroom seemed weird/blurry and bright. I dropped the blanket I was carrying and was hit with inexplicable confusion, I still don't know what I was confused about. I thought I was losing my mind and just stared at the blanket. When I got back to my room I was beginning to get extremely paranoid I was going insane (and based on what I was experiencing I think that would be a typical response) and settled into bed. I was starting to feel better, no more visual distortions and then the headache went away and I felt back to normal. Anecdotally, I feel I should note my cat (not a hallucination) wouldn't leave my side during this episode which is just cute and probably not important but anyway...
    The entire thing lasted about 7-10 minutes but it's hard to be sure. I had experienced some peripheral vision hallucinations before this, which seemed to be a side effect of Adderall as they started to happen after I started to take it. They were all like the one of my cat at my feet - black silhouettes. I pushed this incident to the back of my mind out of fear that I was going insane or had experienced some form of psychosis because of the hallucinations.
    Just this week I stumbled upon simple partial seizures when doing some research for a genetic disease project (I explored epilepsy out of curiosity). I became intrigued when it reminded me of this event because it explained quite a few of the symptoms (flashing lights, visual distortions, etc.) but the episode lasted too long for that to be the explanation and some things just weren't explained by that. I don't know what this was, and I haven't been able to find an explanation. I even explored the possibility of strokes and migraines but nothing fits. I don't want to say anything to a doctor or my parents because they'll probably send me to a psychiatrist and that is not something I'd like to do.
    Still at a loss and confused...
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Has anyone tried speed amphetamine with hidrenitis suppurativa?
    I have suffered with hs since 2006 with upto 15 abcesses and boils under each arm pit at any one time more so in summer. Early this year i ttied taking speed amphetamine for weight loss as I was having no joy as much as I was trying. Due to me being antidrugs I was reluctant to tske it so kept to a low dose so I didn't get the high (april 2014) but due to the low dose, basically the smallest paracetamol capsule u can get filled up to half way with amphetamine On a mMonday Wednesday and Fridayhad no effect on weight loss so much just kicked my metabolism into shape. Slightly** but I did start noticing that the HS had subsided and fewer outbreaks( 1 lump to two every month but small). I MUST STSTE AT THE TIME OF ME STARTING THE AMPHETAMINE MY OUTBREAKS WERE AT THE PERIOD TIME OF MONTH AND NOT ON THE SCALE AS STATED AT BEGININGOF POST.. APPROX 2-3 UNDER EACH ARM BUT WOULD BE QUITE BIG AS THRY WOULD INTERLINK INTO OLD SCARING!! So thinking this was a fluke I stoped taking amphetamine (I was on my 3rd week of taking it) I stopped for 4 weeks and sure enough I had a bad breakout of a large abcess and another two... i stsrted taking it again mid june and have done upto the start of NOV 2014 in this time I have had one outbreak of just one lump on a old operation area And all the small lumps that lay under the skin wwaiting to flare up have either dissappeard or to the size of pin head. I stopped using the amphetamine for 3 weeks I h just started with a lump to same place and some smaller lumps are starting to reappear so I am going back onto it see if it has same effect by suppressing it or whateverIits doing. This year is the first summer I have not had to cover up due to endless messy lumps,no hhospital visits to have op to drain. I AM WRITING THIS POST AS I SENT A MESSAGE TO THE HS SITE IN UK WHERE I LIVE AND A PROFESSOR FROM CARDIFF UNIVERSITY GOT BACK TO ME AND THEY HAVE NEVER HEARD OF ANY CASES OF AMPHETAMINE BEING USED BY PATIENTS THAT HAVE HS. I WANT TO FIND IF ANYONE ELSE HAS AND IF SO WHAT WAS YOUR OUTCOME??? please. ... I believe this maybe a studfy they can do as if it has same effects as on me could help other suffering people. Im not saying its a cure but omg its definitely a break from the agony and discomfort and horrible feeling of having hs.

More questions for: Adderall, Trazodone Hydrochloride

You may be interested at these reviews (Write a review):

  • Belviq (lorcaserin) and adderall (amphetamine and dextroamphetamine)
    I have been on Adderall for more than a year and I have recently started taking Belviq. For some reason a lot of doctors worry about a serious interaction between the two, in my experience the two get along just fine. Adderall helps me stay focused, while Belviq suppresses appetite.
    During the second week of Belviq I did have very small stomach upsets, such as heartburn but it did go away about 2 days later. Other than that the medication works well and I think it is safe for anyone to try who is looking to lose weight. Belviq works on serotonin and while the exact mechanism is unknown it causes appetite suppression in most people. Belviq being one of the medications that are approved for long term use, it may be very helpful to individuals who require a longer period of time on the medication. Belviq reminds me of an antidepressant I was on called Effexor, the two produce the same sense of satisfaction overall, but mostly with food. However Effexor’s side effects (show up around week 7-12) and made it so that the medication is almost impossible to used. Belviq at this time is not giving me any side effects, I think it’s a wonderful drug, much better than the other options like Contrive and Qsyimia. However it’s not for everyone the drug may work perfectly on 80 % of the people who try it but on others it may not. I recommend that the alternatives be considered such as Contrive or Qsymia if Belviq is not found helpful. If Belviq causes you to feel unwell, sad, depressed, or feel like you have the flu—stop taking Belviq and call your doctor as these may be signs of a life threatening condition. Always take the medication as directed by your doctor, do not adjust your own dose without consulting with the doctor.
    Belviq has been a wonderful addition to my life, it’s helped me take control of my body again I feel that the medication is very good, well tolerated, and just an amazingly well designed drug overall.
  • Adderall xr 30 mg and peripheral neuropathy
    I have been taking adderall xr 30 mg for the past five years, with some breaks. I started showing symptoms of peripheral neuropathy the second year. This year (my 5th year on adderall) has been the worst and most difficult for my peripheral neuropathy. I also suffer from major depressive disorder and HSV, and I have heard that both of them may be related to peripheral neuropathy.
  • I need advise, badly ckd!! (1 response)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!
  • Hit and miss sleep with dextroamphetamine
    Started drug 2 months ago and have seen an improvement in my focus. Ziprosidone for my depression causes me to get dead tired by 7 pm. Once I started taking Dextroamphetamine I started having insomnia 2 times a week. I think I would rather sleep early than stay up all night and then try and stay awake at work. So many drugs and even more side effects. Also Trazadone is no help for getting me to sleep. The only good side affect I have seen is I am down 26 pounds.
  • Michael my son died as a result of kolopin & ambien (5 responses)
    My beautiful son to whom I depended upon took his Life by suicide on July 16, 2013. He had been struggling with a sleep disorder. It seemed to begin in his last year of high school 2010. Mike was very strong in mind and in body. He became a certified personal trainer. He encouraged everyone around him and all of his clients. How can someone so strong be so weak?
    He had been heavily medicated by a sleep doctor, for years this doctor gave him different medicines and he began to show other heath impairments..I could not see so many things that are very clear to me now, I never saw the effect the drugs had on him. he was growing more tired and withdrawn. He knew so much about medicines that I thought he knew what was happening he and I both trusted the doctors. With each new problem that occurred there was always a new drug to try and along with it a new set of side effects. A new doctor was added to his care and this doctor right away gave an RX for Kolopin. He was already taking Ambien and the two dont seem to play well together. Mean while he was growing sicker and sicker. We constantly were going for this test or that test, never once did the sleep doctor ever think that the drugs being given were the cause of all of his distress.
    At one point he was unable to keep food down and was throwing up every day. More test that always revealed the same result. No problem found. The visits to the sleep doctor were the same as well his condition was worsening and chronic. and yet never once did the sleep doctor ever give the drugs a second thought. The known side effects for both of these drugs were suicide for ages between 16 to 22. Until his death I never read about any of the products he was on.
    On July 16, 2013 the day began with Mike not sleeping, he seemed angry, exhausted. he was getting ready to help us out at our office. Once there it seemed like nothing went his way and at one point got into argument with his dad, told me he hated him and decided to go into his office to talk to him. He began to cry, I had to leave for an appointment and I waved to him through a window. I could see him crying. He got up and just left our office. Later we would find that he called his pastor, his cousins and a friend all did not reply. One girl friend of his did, she told him to meet her for drinks he told her what happened and he needed to save money and needed to be at his training job shortly. Within a 15 minute span wrote us a suicide letter, drove off and shot himself. a few minutes after he did a passer bye called 911. They took him to the hospital. The police came to our office to inform us we need to get to the hospital. The shock of all shock.... He passed away 1:04 am on the 17 of July. I never thought I could be so lost and broken as I am. I miss you so much Michael!

More reviews for: Adderall, Trazodone Hydrochloride

Comments from related studies:

  • From this study (1 week ago):

  • After 3-4 days of taking adderall or any stimulants I start to get pimple like sores on my scalp, nose,eyes,mouth,face and vaginal area puss comes out of mi eyes and vaginal area.
    It seems like every hair follicle or cut becomes clogged and filled with puss. It burns when I use the restroom. My eyes and nose burns and itches. My tongue and mouth also gets pimples on them. When I break out then my husband also does then when he has taken adderall he also has the same symptoms it only gets better if I stop the adderall or use a prescription med for herpes.

    Reply

  • From this study (2 months ago):

  • I just started taking Atorvastatin 2 months ago and have started losing a lot of hair.

    Reply

  • From this study (3 months ago):

  • My WBC count has been low for 4mos now. I'm lethargic, having problems sleeping & still experiencing a tremendous amount of pain (which I believe it has to do with the congenital lipoma on my brain stem-I've had excruciating pain as long as I can remember.)

    Reply

    really? on Sep, 22, 2014:

    I honestly thought this was a board where we could all learn from
    Each other's experiences. Unfortunately, everyone seems to be fixated on this one poster, asking a question for a "friend" & who is supposedly mixing all types of drugs. Let's get off of the 3rd party bashing because anyone on all of those drugs needs a lot more than people on a web page. Geez!!!!

    Reply

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Complete drug side effects:

On eHealthMe, Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) is often used to treat attention deficit hyperactivity disorder. Trazodone Hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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