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Review: taking Advil and Amphetamine salt combo together

Summary: drug interactions are reported among people who take Advil and Amphetamine salt combo together. This review analyzes the effectiveness and drug interactions between Advil and Amphetamine salt combo. It is created by eHealthMe based on reports of 468 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


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What are the drugs

Advil has active ingredients of ibuprofen. It is often used in headache. (latest outcomes from 22,825 Advil users)

Amphetamine salt combo has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from 371 Amphetamine salt combo users)

On May, 15, 2015: 468 people who take Advil, Amphetamine salt combo are studied

Advil, Amphetamine salt combo outcomes

Drug combinations in study:
- Advil (ibuprofen)
- Amphetamine salt combo (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Advil is effective33.33%
(8 of 24 people)
(2 of 15 people)
(4 of 9 people)
(2 of 8 people)
(4 of 15 people)
(5 of 15 people)
(6 of 13 people)
(2 of 5 people)
Amphetamine salt combo is effective55.00%
(11 of 20 people)
(9 of 18 people)
(8 of 13 people)
(11 of 19 people)
(15 of 29 people)
(5 of 10 people)
(4 of 4 people)

Drug effectiveness by gender :

Advil is effective33.33%
(26 of 78 people)
(7 of 26 people)
Amphetamine salt combo is effective57.83%
(48 of 83 people)
(15 of 28 people)

Drug effectiveness by age :

Advil is effectiven/an/a18.18%
(2 of 11 people)
(8 of 49 people)
(5 of 25 people)
(8 of 78 people)
(7 of 17 people)
(3 of 19 people)
Amphetamine salt combo is effectiven/an/a45.45%
(5 of 11 people)
(23 of 55 people)
(13 of 27 people)
(11 of 83 people)
(9 of 17 people)
(2 of 25 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainShortness Of BreathPulmonary EmbolismExhaustion, Fatigue, Lethargy, Tiredness, WearinessPainChest PainDepressionPain
SomnolenceNauseaDeep Vein ThrombosisMuscle AtrophyNauseaDyspnoeaAnxietyAnxiety
Abdominal Pain UpperFatigueInjuryDifficulty In BreathingCholecystitisPulmonary EmbolismNeck PainDyspnoea
AnxietyWeight IncreasedPainFatigueChillsEczema NummularAggressionDepression
Loss Of ConsciousnessAnxiety AggravatedThrombophlebitis SuperficialMuscle SprainCholelithiasisMuscle AchesAbnormal BehaviourDeep Vein Thrombosis
HeadacheHeadacheAnxietyLethargyDiarrhoeaEczemaSuicide AttemptFatigue
ContusionLipase IncreasedJoint SwellingEmotional DisorderAbdominal Pain UpperStress And AnxietyIntentional OverdoseInjury
Emotional DistressPancreatitisThrombocytopeniaDyskinesiaCholecystitis ChronicDystoniaVith Nerve ParalysisDizziness
Rash PruriticMuscle FatiguePain In ExtremityCoughVomitingFlat AffectIntracranial Venous Sinus ThrombosisInsomnia
UrticariaIleusFatigueNarcotic AbuseSphincter Of Oddi DysfunctionDegenerative Joint DiseaseDeep Vein ThrombosisVomiting

Most common drug interactions by gender * :

PainGastrooesophageal Reflux Disease
Deep Vein ThrombosisArthralgia
AnxietyAttention Deficit/hyperactivity Disorder
Pulmonary EmbolismFatigue
Gallbladder DisorderGastrointestinal Disorder
FatigueInflammatory Bowel Disease
NauseaIntestinal Haemorrhage

Most common drug interactions by age * :

n/aDyspnoeaAbdominal Pain UpperGallbladder DisorderVomitingAnxietyFatigueRenal Failure
Heart Rate IncreasedPainDyspnoeaCholelithiasisPainDyspnoeaContusion
Accidental ExposureHeadacheAttention Deficit/hyperactivity DisorderPulmonary EmbolismInjuryParaesthesiaPatella Fracture
DisorientationCholecystitis ChronicGastrooesophageal Reflux DiseaseCholecystitisVomitingMuscle SpasmsFemur Fracture
Hallucination, VisualDeep Vein ThrombosisDry SkinInjuryEmotional DistressTardive DyskinesiaSpinal Column Stenosis
StomatitisFatigueGastrointestinal DisorderInsomniaDizzinessDehydrationDelirium
AgitationAbdominal PainInflammatory Bowel DiseaseDeep Vein ThrombosisHyperhidrosisTremorGait Disturbance
DepressionIntestinal HaemorrhageChest PainMultiple Drug OverdoseDysphagiaRhabdomyolysis
AnxietyMulti-organ DisorderNauseaLoss Of ConsciousnessDystoniaFall
VomitingEczemaAbdominal Pain UpperMental DisorderInfluenza Like IllnessFibula Fracture

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Advil and Amphetamine salt combo?


You are not alone! Join a related support group:
- support group for people who take Advil
- support group for people who take Amphetamine Salt Combo

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More reviews for: Advil, Amphetamine salt combo

Comments from related studies:

  • From this study (4 months ago):

  • I think it was brought on by the Suboxone. I took 3-4 a day for approximately 4 years starting 11 years ago. Stopped them but realized they were helping with my depression. After trying every antidepressant with no help the Suboxone was wonderful. I got back on it but only taking 2-3 a day for another 2-3 years. Insurance stopped paying about 9 months ago. I continued to take them, but only 1 a day for another 1-2 years. Now, I take 1 occasionally. When I completely stopped the neuropathy gradually began. It was around Sept. I began to notice my feet felt like they were numb. With shoes on I felt like they were wet. I also noticed getting weaker and my family noticed I was walking slow, etc. Feel terrible with terrible problem of something like hot flashes, but those were over years ago. Have lots of nausea. My doctor used some type instrument and I have very little feeling on the bottom of my feet. He is sending me to a neurologist.


  • From this study (11 months ago):

  • Fatigue has been getting worse since 2009. CKD stage 3 diagnosed July 2014.


  • From this study (1 year ago):

  • in the last year I have had significant increase in bilateral hip joint pain with effusion, I have spent the last 1.5 years driving approx. 200 miles 5 days per week, I am a nurse


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Complete drug side effects:

On eHealthMe, Advil (ibuprofen) is often used to treat pain. Amphetamine Salt Combo (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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