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Review: taking Allegra and Zantac together

Summary: drug interactions are reported among people who take Allegra and Zantac together.

This review analyzes the effectiveness and drug interactions between Allegra and Zantac. It is created by eHealthMe based on reports of 1,401 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 22, 2015: 1,401 people who take Allegra, Zantac are studied

Allegra, Zantac outcomes

Drug combinations in study:
- Allegra (fexofenadine hydrochloride)
- Zantac (ranitidine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Allegra is effective16.67%
(1 of 6 people)
(0 of 8 people)
(0 of 2 people)
(2 of 4 people)
(7 of 11 people)
(1 of 4 people)
(1 of 2 people)
Zantac is effective25.00%
(2 of 8 people)
(2 of 10 people)
(1 of 5 people)
(2 of 5 people)
(2 of 6 people)
(0 of 2 people)
(1 of 3 people)

Drug effectiveness by gender :

Allegra is effective34.48%
(10 of 29 people)
(2 of 8 people)
Zantac is effective26.67%
(8 of 30 people)
(2 of 9 people)

Drug effectiveness by age :

Allegra is effectiven/an/a100.00%
(1 of 1 people)
(1 of 7 people)
(3 of 21 people)
(2 of 17 people)
(3 of 25 people)
(2 of 15 people)
Zantac is effective0.00%
(0 of 1 people)
(1 of 1 people)
(0 of 7 people)
(2 of 22 people)
(3 of 17 people)
(2 of 25 people)
(2 of 15 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Abdominal PainAbdominal PainErythema MultiformeNauseaFractureDystoniaParaesthesiaDyspnoea
Febrile NeutropeniaDizzinessCholecystitis ChronicVomitingCardiac Failure CongestiveHippusWeaknessPain
HypokalaemiaAspartate Aminotransferase IncreasedLiver Function Test AbnormalHyperglycaemiaUpper Limb FracturePlatelet CountUrination - Bed WettingAnxiety
NeutropeniaSeborrhoeic KeratosisPulmonary EmbolismType 2 Diabetes MellitusType 2 Diabetes MellitusParaesthesiaPainful RespirationDizziness
Liver Carcinoma RupturedDrug Exposure During PregnancyPainPelvic Fluid CollectionRib FractureChest PainUrinary FrequencyFall
PyrexiaDyspnoeaDepressionPneumoniaLower Limb FractureWeaknessNausea
Platelet Count DecreasedLiver Function Test AbnormalGallbladder DisorderRespiratory FailureOsteoporosisSuicidal IdeationChest Pain
RashHaemorrhoidsMental DisorderHyponatraemiaCoronary Artery DiseaseFatigue
PneumoniaNasal DisorderInjuryIschaemiaRenal Failure ChronicDiarrhoea
Aspartate Aminotransferase IncreasedVentricular FibrillationDrug Exposure During PregnancyMetabolic AcidosisErythema MultiformeDepression

Most common drug interactions by gender * :

AnxietyChest Pain
Back PainHypercholesterolaemia
Chest PainMyalgia

Most common drug interactions by age * :

Peritoneal EffusionInsomniaNauseaPruritusChest PainChest PainChest PainDiarrhoea
Pleural EffusionSudden DeathFatiguePainAnxietyNauseaDizzinessFall
Pelvic Fluid CollectionUnresponsive To StimuliDeep Vein ThrombosisNauseaDyspnoeaDyspnoeaNauseaDyspnoea
Pancreatitis AcuteVomitingCerebrovascular AccidentAnxietyPainHeadachePainAnxiety
PancreatitisAgitationDepressionCholecystitis ChronicNauseaDepressionFallBone Disorder
PneumoniaArrhythmiaBrain HerniationDyspnoeaUrticariaFallVomitingCough
PyrexiaAggressionBrain DeathThroat TightnessInjuryBack PainArthralgiaFatigue
Type 2 Diabetes MellitusDyspnoeaDrug HypersensitivityInjuryDrug IneffectiveAbdominal PainBack PainMyalgia
VomitingCoughCerebral IschaemiaDrug Exposure During PregnancyHeadacheAnxietyHeadachePain
Respiratory FailureDry ThroatDrug IneffectiveUrticariaPain In ExtremityPainAnxietyChest Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Allegra
- support group for people who take Zantac

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Allegra (fexofenadine hydrochloride) is often used to treat allergies. Zantac (ranitidine hydrochloride) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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