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Review: Allopurinol and Colcrys





Summary: drug interactions are reported among people who take Allopurinol and Colcrys together.

This review analyzes the effectiveness and drug interactions between Allopurinol and Colcrys. It is created by eHealthMe based on reports of 494 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Allopurinol and Colcrys >>>

What are the drugs

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from Allopurinol 51,438 users)

Colcrys has active ingredients of colchicine. It is often used in gout. (latest outcomes from Colcrys 598 users)

On Dec, 14, 2014: 494 people who take Allopurinol, Colcrys are studied

Allopurinol, Colcrys outcomes

Drug combinations in study:
- Allopurinol (allopurinol)
- Colcrys (colchicine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Allopurinol is effective66.67%
(2 of 3 people)
21.43%
(3 of 14 people)
0.00%
(0 of 4 people)
16.67%
(1 of 6 people)
44.44%
(4 of 9 people)
50.00%
(1 of 2 people)
37.50%
(3 of 8 people)
66.67%
(2 of 3 people)
Colcrys is effective33.33%
(2 of 6 people)
20.00%
(2 of 10 people)
33.33%
(3 of 9 people)
50.00%
(2 of 4 people)
22.22%
(2 of 9 people)
75.00%
(3 of 4 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DiarrhoeaDiarrhoeaPain In ExtremityDrug IneffectiveHigh Blood PressureGoutNauseaGout
NauseaPyrexiaUrinary IncontinenceProstate CancerGouty ArthritisMuscle TwitchingSwelling Of The Ankles - Feet - LegsNausea
VomitingDyspepsiaOedema PeripheralProstatic Specific Antigen IncreasedAcid RefluxSwelling Of The Ankles - Feet - LegsRed EyeDiarrhoea
MyalgiaConstipationMyocardial InfarctionInsomniaAllergiesNauseaGoutPyrexia
AstheniaBack PainMacular DegenerationTinnitusPolyarthralgiaDelayed UrinationBrittle NailsWeight Decreased
Oedema PeripheralColitisVenous OcclusionErectile DysfunctionThrombocytopeniaChest PainLymphoedemaVomiting
ErythemaHyperkalaemiaStomach PainPsychosis AggravatedRinging In The EarsLymphoedemaMuscle TwitchingCondition Aggravated
DizzinessMetabolic AcidosisTremorGoutErectile DysfunctionDelayed UrinationDrug Ineffective
Drug IneffectiveVomitingAgitationStomach PainDiarrhoeaBlood Pressure DecreasedCardiac Failure Congestive
Electroencephalogram AbnormalWeight DecreasedBlood Pressure IncreasedRectal BleedingPruritus

Drug effectiveness by gender :

FemaleMale
Allopurinol is effective20.00%
(1 of 5 people)
34.09%
(15 of 44 people)
Colcrys is effective25.00%
(1 of 4 people)
36.36%
(16 of 44 people)

Most common drug interactions by gender * :

FemaleMale
GoutGout
DiarrhoeaPyrexia
NauseaNausea
MalaiseBlood Creatinine Increased
VomitingDrug Ineffective
HypertensionCondition Aggravated
Weight DecreasedWeight Decreased
Oedema PeripheralDiarrhoea
Condition AggravatedCardiac Arrest
Blood Cholesterol IncreasedCardiac Failure Congestive

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Allopurinol is effectiven/an/an/a0.00%
(0 of 5 people)
33.33%
(1 of 3 people)
25.00%
(2 of 8 people)
21.43%
(3 of 14 people)
29.41%
(10 of 34 people)
Colcrys is effectiven/an/an/a20.00%
(1 of 5 people)
66.67%
(2 of 3 people)
42.86%
(3 of 7 people)
21.43%
(3 of 14 people)
23.53%
(8 of 34 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aHaemoglobin DecreasedHypertensive CrisisGoutNauseaGout
Muscle WeaknessPeripheral ColdnessPyrexiaPruritusDiarrhoea
Aplastic AnaemiaDecreased AppetiteCondition AggravatedPyrexiaNausea
Bone Marrow Depression NosVomitingNauseaOedema PeripheralCardiac Failure Congestive
Haematocrit DecreasedAspartate Aminotransferase IncreasedErythema MultiformeHepatic SteatosisDrug Ineffective
Tuberculosis NosNeuralgiaCoughWeight DecreasedAsthenia
NocardiosisDyspnoeaDermatitis NosMalaiseCondition Aggravated
Pneumocystis Carinii InfectionHaematocheziaStevens Johnson SyndromeHyperkalaemiaFatigue
Pulmonary HaemorrhageBlood Lactate Dehydrogenase IncreasedEcchymosisTendonitisBlood Creatinine Increased
ToxoplasmosisRestless Legs SyndromePruritusGoutMalaise

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Allopurinol and Colcrys?

You are not alone! Join a related mobile support group:
- support group for people who take Allopurinol and Colcrys
- support group for people who take Allopurinol
- support group for people who take Colcrys

Can you answer these questions (Ask a question):

More questions for: Allopurinol, Colcrys

You may be interested at these reviews (Write a review):

  • Allop├╝rinol and achilles tendinitis
    I take allopurinol on a purely prophylactic basis, as my father has got gout and kidney stones. Since three months I suffer from achilles tendinitis; I put it down to overload; I am rather heavy and play a lot of tennis, besides moving a lot at work. As always, I tried to "walk through" my weight associated problems, but it did not get any better. Non-compliant, I stopped taking allopurinol for the last three days, and, surprise surprise, the pain is quickly abating, in spite of playing prolonged matches the last three days. I remembered that gyrase inhibitors (e.g. ciprofloxacin) predispose to achilles tendon rupture, a fact that I was personal witness with a female player at our club. So I speculate on a causal link between allopurinol and achilles tendinitis
  • Allopurinol for 6-mp metabolism to 6-tgn
    I began taking Allopurinol 100mg to help metabolize the Purinethol I have been taking for 6 years for Crohn's disease after a blood test revealed my 6-MMP metabolites were too high and 6-TG were too low. Several published studies show Allopurinol to be helpful for "non-preferential metabolizers" like me, to help shunt the metabolic pathway towards therapeutic 6-TG.

    After 1 week of Allopurinol, I had to discontinue the drug due to debilitating nausea, which was worst in the morning.
  • Ear pain from allopurinol 100mg (1 response)
    I have just been prescribed 100mg Allopurinol.
    1 a day.
    I am in my second day of taking these tablets.
    I have begun to get get a sudden pain in my ear.
    I have never in all my years have ever had such a pain.
    I know the only change that has happened around me is taking these tablets.
    I have stopped taking these and am awaiting my next appt with my GP.
    I do take Arcoxia with paracetemol for pain relief.
  • Allopurinol and muscle cramps
    Approximately 5 years ago I developed gout and my physician prescribed allopurinol. After a period of time I began to have muscle spasms in the calves of my legs at night. My doctor gave me a prescription for restless leg syndrome, which helped for a short time. I was then given a different prescription when that one no longer helped, and finally a third prescription, which did not work either. The cramps continued to grow more severe and more frequent. I was also having extremely severe cramps in my left hand, to the point that I could not straighten my fingers for several excruciating minutes. Although the cramps in my calves had lessened significantly, my toes were starting to cramp severely.



    I stopped taking allopurinol about a month ago, and since then I realized that my hands and toes were cramping less and less, and now it is almost completely gone. I inadvertently stopped the allopurinol and I lost the bottle of pills and didn't realize it until I went to refill my pill box that holds a month's supply divided into daily doses. I searched on the internet and found that muscle problems are not uncommon for some people taking allopurinol.

More reviews for: Allopurinol, Colcrys

Comments from related studies:

  • From this study (3 months ago):

  • Seems to flare up each time more severe than the last

    Reply

  • From this study (9 months ago):

  • I am curious to know if the Allopurinol can increase blood sugar, though I gained up to 10 lbs since I first started taking this med, I think in part due to less exercise on my part.

    Reply

  • From this study (11 months ago):

  • I also take a drug called Moxonidine for High Blood pressure.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Allopurinol (allopurinol) is often used to treat gout. Colcrys (colchicine) is often used to treat gout. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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