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Review: Alphagan and HCTZ

This review analyzes the effectiveness and drug interactions between Alphagan and HCTZ. It is created by eHealthMe based on reports of 217 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Alphagan and HCTZ >>>

What are the drugs

Alphagan (latest outcomes from 3,400 users) has active ingredients of brimonidine tartrate. It is often used in glaucoma.

Hctz (latest outcomes from 1,119 users) has active ingredients of hydrochlorothiazide. It is often used in high blood pressure.

On Jul, 27, 2014: 217 people who take Alphagan, HCTZ are studied

Alphagan, HCTZ outcomes

Drug combinations in study:
- Alphagan (brimonidine tartrate)
- HCTZ (hydrochlorothiazide)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Alphagan is effectiven/a0.00%
(0 of 1 people)
(0 of 1 people)
(0 of 1 people)
(1 of 1 people)
HCTZ is effectiven/an/an/a0.00%
(0 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal Failure AcuteLoss Of Consciousnessn/aPruritusn/aEmotional Distressn/aDyspnoea
SyncopeNauseaLymphocyte Count DecreasedHypertensionOedema Peripheral
Sepsis SyndromeRhinorrhoeaCataractMental DisorderAsthenia
Renal Tubular NecrosisSyncopeFatiguePulmonary EmbolismFall
Mental Status ChangesHypersensitivityDizzinessCardiac MurmurSyncope
HypertensionFatigueChromatopsiaArthropathyLoss Of Consciousness
Loss Of ConsciousnessAstheniaDizzinessInsomnia
AmnesiaBlood Pressure AbnormalTinnitusVomiting
Ankle FractureBlood Pressure DecreasedPneumonia
Syncope VasovagalEye RednessHypertension

Drug effectiveness by gender :

Alphagan is effective33.33%
(1 of 3 people)
(0 of 1 people)
HCTZ is effective100.00%
(1 of 1 people)
(0 of 1 people)

Most common drug interactions by gender * :

DyspnoeaIntraocular Pressure Increased
Oedema PeripheralSyncope
VomitingRenal Failure Acute
PainMental Status Changes
FallBlood Urea Increased
Loss Of ConsciousnessAsthenia
AstheniaWeight Decreased
HypoaesthesiaSepsis Syndrome
SyncopeRenal Tubular Necrosis

Drug effectiveness by age :

Alphagan is effectiven/an/an/an/an/an/a0.00%
(0 of 1 people)
(1 of 4 people)
HCTZ is effectiven/an/an/an/an/an/a100.00%
(1 of 1 people)
(0 of 1 people)

Most common drug interactions by age * :

Haemoglobin DecreasedScotomaLoss Of Consciousness
Neutrophil Count DecreasedEye PainVomiting
Oral PainHeadacheAsthenia
PancytopeniaRetinal ScarPneumonia
Haematocrit DecreasedOptic Ischaemic NeuropathySyncope
Urinary IncontinenceRetinal AneurysmFall
SyncopeOptic AtrophyInsomnia
TinnitusVitreous HaemorrhageOedema Peripheral

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Alphagan and HCTZ
- group for people who take Alphagan
- group for people who take HCTZ

Comments from related studies:

  • From this study (1 year ago):

  • Right shoulder pain, clavicle pain, left knee pain, right lower leg pain, stiff joints on right hand more severe after being in bed for 4 hours or more.
    Blood pressure higher 140/82 to 170/84 when measured between 2 am to 4:30 am. Difficulty staying asleep because of pain.


  • From this study (1 year ago):

  • After a 4 month trial of Lumigan, stopped because of onset of bilateral tinnitus and fullness of ears. Started Alphagan and fullness went away but tinnitus persists! ENT said she doesn't see any hearing loss on test and thinks its random. I hold to the fact that it Started with Lumigan and hasn't gone away with Alphagan.. ophthalmologist says its not the drops.....?????


  • From this study (5 years ago):

  • osteoperosis and spinal deterioration within a year. Was tested right before and had none of these conditions.


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More reviews for: Alphagan, HCTZ

Complete drug side effects:

On eHealthMe, Alphagan (brimonidine tartrate) is often used to treat glaucoma. Hctz (hydrochlorothiazide) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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