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Review: taking Alprazolam and Buspar together

Summary: drug interactions are reported among people who take Alprazolam and Buspar together.

This review analyzes the effectiveness and drug interactions between Alprazolam and Buspar. It is created by eHealthMe based on reports of 1,391 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 9, 2015: 1,391 people who take Alprazolam, Buspar are studied

Alprazolam, Buspar outcomes

Drug combinations in study:
- Alprazolam (alprazolam)
- Buspar (buspirone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Alprazolam is effective40.00%
(4 of 10 people)
(5 of 12 people)
(6 of 10 people)
(10 of 20 people)
(9 of 12 people)
(13 of 14 people)
(4 of 5 people)
Buspar is effective12.50%
(2 of 16 people)
(3 of 19 people)
(3 of 10 people)
(4 of 12 people)
(3 of 7 people)
(4 of 7 people)
(2 of 3 people)

Drug effectiveness by gender :

Alprazolam is effective63.24%
(43 of 68 people)
(8 of 15 people)
Buspar is effective31.67%
(19 of 60 people)
(2 of 14 people)

Drug effectiveness by age :

Alprazolam is effectiven/a100.00%
(1 of 1 people)
(1 of 2 people)
(8 of 18 people)
(19 of 92 people)
(9 of 34 people)
(11 of 31 people)
(2 of 9 people)
Buspar is effectiven/a0.00%
(0 of 1 people)
(2 of 17 people)
(9 of 88 people)
(6 of 34 people)
(3 of 29 people)
(1 of 8 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Suicide AttemptDizzinessBlood Triglycerides IncreasedType 2 Diabetes MellitusCholecystitis ChronicAnxietyNervous System DisorderAnxiety
Intentional OverdoseBurning SensationBlood Cholesterol IncreasedDiabetic NephropathyPainWeight IncreasedNasal CongestionDepression
AggressionPalpitationsDiabetic NeuropathyDiabetes Mellitus Inadequate ControlGallbladder DisorderFood CravingPanic AttackNausea
ScarAnxietyMusculoskeletal DisorderNeuropathy PeripheralDizzinessFearParaesthesiaPain
PainTremorType 2 Diabetes MellitusDecubitus UlcerSphincter Of Oddi DysfunctionHyperglycaemiaParosmiaChest Pain
Bipolar I DisorderNervousnessNeuropathy PeripheralDizzinessPancreatitisInsomniaNail DisorderFatigue
DysphagiaFeeling AbnormalBack PainCryingFatigueSuicidal IdeationMyofascial Pain SyndromeDyspnoea
Memory ImpairmentFallSpinal Column StenosisAcid RefluxDepressionMajor DepressionHypoaesthesiaDizziness
Burns Third DegreeJoint InjuryHyperlipidaemiaGrand Mal ConvulsionAnxietyPollakiuriaMental DisorderFall
DepressionHaemorrhageHeadacheHeadacheDiarrhoeaExhaustion, Fatigue, Lethargy, Tiredness, WearinessMuscular WeaknessInsomnia

Most common drug interactions by gender * :

Chest PainFatigue
PainSuicidal Ideation
Oedema PeripheralDrug Ineffective
FatigueChest Pain

Most common drug interactions by age * :

Diabetes Mellitusn/aPainDepressionCompleted SuicideAnxietyFatigueDizziness
HyperglycaemiaDepressionAnxietyDiabetes MellitusDepressionFallNausea
Food CravingGallbladder DisorderDyspnoeaType 2 Diabetes MellitusInsomniaDepressionDyspnoea
FearSphincter Of Oddi DysfunctionPanic AttackSuicide AttemptChest PainAnxietyFall
InjuryPancreatitisHeadacheNauseaPainNauseaConfusional State
AnxietyCholecystitis ChronicChest PainDrug Toxicity NosType 2 Diabetes MellitusCompleted SuicideCardiac Failure Congestive
Major DepressionSubstance AbuseHyperhidrosisDepressionSuicidal IdeationDrug IneffectiveFatigue
Weight IncreasedConfusional StateBlood Cholesterol IncreasedDiabetes Mellitus Inadequate ControlOedema PeripheralInsomniaAnxiety
Suicidal IdeationMental ImpairmentFatigueDyspepsiaHeadacheChest PainSyncope
PollakiuriaDehydrationDizzinessDrug Withdrawal SyndromeNauseaDizzinessPain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Alprazolam
- support group for people who take Buspar

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Alprazolam (alprazolam) is often used to treat stress and anxiety. Buspar (buspirone hydrochloride) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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