Review: Ambien and Benadryl
This review analyzes the effectiveness and drug interactions between Ambien and Benadryl. It is created by eHealthMe based on reports of 2,332 people who take the same drugs from FDA and social media, and is updated regularly.
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What are the drugs
Ambien (latest outcomes from 46,710 users) has active ingredients of zolpidem tartrate. It is often used in insomnia.
Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.
On Oct, 30, 2014: 2,332 people who take Ambien, Benadryl are studied
Drug combinations in study:
- Ambien (zolpidem tartrate)
- Benadryl (diphenhydramine hydrochloride)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Ambien is effective||41.18%|
(7 of 17 people)
(3 of 6 people)
(8 of 15 people)
(3 of 12 people)
(10 of 19 people)
(5 of 7 people)
(1 of 2 people)
(0 of 1 people)
|Benadryl is effective||35.71%|
(5 of 14 people)
(4 of 13 people)
(2 of 5 people)
(3 of 10 people)
(6 of 11 people)
(0 of 10 people)
(3 of 9 people)
(2 of 4 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Pyrexia||Small Intestinal Obstruction||Dizziness||Bronchospasm||Depression||Pain||Fatigue||Pain|
|Hypotension||Rhinorrhoea||Disturbance In Attention||Psychiatric Symptom||Dysarthria||Oedema Peripheral||Sex - Delayed Ejaculation||Anxiety|
|Dyspnoea||Implant Site Erosion||Dysarthria||Trisomy 21||Impaired Driving Ability||Eating Disorder||Drug Dependence||Nausea|
|Dehydration||Deep Vein Thrombosis||Gait Disturbance||Jaundice Neonatal||Lacrimation Increased||Amnesia||Depression||Dyspnoea|
|Pain In Extremity||Anxiety||Depression||Spinal X-ray Abnormal||Somnambulism||Somnambulism||Anxiety||Arthralgia|
|Malaise||Pulmonary Embolism||Confusional State||Atrial Septal Defect||Ocular Hyperaemia||Arthralgia||Sleepy||Fatigue|
|Asthenia||Folliculitis||Anger||Congenital Mitral Valve Incompetence||Road Traffic Accident||Respiration Abnormal||Hot Flashes||Back Pain|
|Atrial Fibrillation||Atrial Fibrillation||Asthenia||Heart Rate Irregular||Balance Disorder||Deep Vein Thrombosis||Dermatitis Acneiform||Pyrexia|
|Lymphopenia||Platelet Count Decreased||Bradyarrhythmia||Oxygen Saturation Decreased||Memory Impairment||Chest Pain||Proteinuria||Anaemia|
|Confusional State||Asthenia||Impaired Work Ability||Ringing In The Ears||Spinal X-ray Abnormal||Dyspnoea Exertional||Sweating Increased||Vomiting|
Drug effectiveness by gender :
|Ambien is effective||47.46%|
(28 of 59 people)
(9 of 20 people)
|Benadryl is effective||34.55%|
(19 of 55 people)
(6 of 21 people)
Most common drug interactions by gender * :
|Osteonecrosis Of Jaw||Asthenia|
Drug effectiveness by age :
|Ambien is effective||n/a||n/a||50.00%|
(3 of 6 people)
(3 of 22 people)
(6 of 29 people)
(13 of 29 people)
(7 of 31 people)
(5 of 10 people)
|Benadryl is effective||n/a||n/a||16.67%|
(1 of 6 people)
(4 of 22 people)
(5 of 30 people)
(9 of 27 people)
(5 of 29 people)
(1 of 10 people)
Most common drug interactions by age * :
|Respiratory Arrest||Transfusion Reaction||Agitation||Insomnia||Pain||Pain||Anxiety||Fall|
|Cardiac Arrest||Hypokalaemia||Pyrexia||Nausea||Pyrexia||Back Pain||Pain||Anaemia|
|Poisoning||Fungal Test Positive||Headache||Vomiting||Dyspnoea||Anxiety||Dyspnoea||Fatigue|
|Convulsion||Rash||Convulsion||Urinary Tract Infection||Headache||Nausea||Injury||Dyspnoea|
|Aggression||Bronchiectasis||Musculoskeletal Stiffness||Asthenia||Abdominal Pain||Pain In Extremity||Nausea||Anxiety|
|Drug Toxicity||Culture Positive||Suicidal Ideation||Anxiety||Depression||Arthralgia||Osteonecrosis Of Jaw||Back Pain|
|Orthostatic Hypotension||Respiratory Tract Infection Fungal||Weight Increased||Upper Respiratory Tract Infection||Fatigue||Fall||Arthralgia||Nausea|
|Tremor||Stem Cell Transplant||Respiratory Distress||Weight Decreased||Insomnia||Insomnia||Pyrexia||Pain|
|Pneumonia||Restrictive Pulmonary Disease||Pneumonia||Multi-organ Failure||Chest Pain||Depression||Insomnia||Osteonecrosis Of Jaw|
|Renal Impairment||Tracheomalacia||Blood Potassium Decreased||Pericardial Effusion||Anxiety||Headache||Bone Disorder||Arthralgia|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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You are not alone! Join a related mobile support group:
- support group for people who take Ambien and Benadryl
- support group for people who take Ambien
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Can you answer these questions (Ask a question):
- What can i do to help my wife who is on ambien and sometimes has horrible restless leg syndrome?
(Asked by a 25 year old woman who has ADD, Restless Leg Syndrome, Insomnia, and takes Adderall, Ambien)
She will take her meds like a hour and a half before actually going to sleep. The Zambian that is and sometimes she has uncontrolled restless leg syndrome. She has to move them a certain way and everything. This last time it lasted a hour and a half. I was just wondering if there is anything I could ...
- What causes a headache only when coughing or shaking the head?
(Asked by a 57 year old man who has Headache, and takes Benadryl)
Head hurts only when shaken or I cough. I suspect benadryl or amytriptaline
- Does zoloft cause ringing in the ears, like tinnitus? i've been on it for a month and noticed the ringing in the ears about a week ago, and it's just constant ringing and it's driving me insane.
(Asked by a 24 year old man who has Ringing In The Ears, and takes Dicyclomine Hydrochloride, Benadryl, Tylenol, Lialda, Azathioprine, Prednisone, Ambien, Zoloft)
I've been on most of the medications for more than a year and it hasn't been that bad getting used to them. But I've been on Zoloft and ambien for about a month now, and I've been noticing a lot of side effects. The one I just recently noticed and that has been driving me completely insane, is the r ...
- I have a-fib after taking benadryl. i've been off it for a few days, but flutters remain. how long does it last?
(Asked by a 86 year old woman who has Atrial Fibrillation/flutter, and takes Benadryl)
I took 6 pills a day for a week, have been off medication for several days, but A-Fib symptoms continue.
- Can ambien causing euphoria and the jitters
(Asked by a 19 year old boy who has Adjustment Disorder With Mixed Anxiety And Depressed Mood, Feeling Jittery, and takes Ambien)
After taking the ambien to help me sleep I feel euphoric and jittery rather than calmed. I take an anti-depressant in the morning composed of M folic acids.
You may be interested at these reviews (Write a review):
- Nightmare on benadryl
(Posted by a 54 year old man who has Nightmare, Hard Time Sleeping, and takes Benadryl)
After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I ...
- Benadryl completed suicide 50 year old
(Posted by a 50 year old woman who has Completed Suicide, and takes Alcohol, Methenamine Hippurate, Xanax, Benadryl)
My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.
- Had nms in 2005, will trileptal increase chance of recurrence?
(Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...
- Zolpidem er side effects
(Posted by a 60 year old woman who has Bipolar Ii Disorder, Sleeping Difficulty, and takes Zolpidem Tartrate)
I was in this medicaion for 2 weeks.I had severe headache,muscular backache and a rash in one side of my body.I didn't had problems falling asleep but I had problems staying asllep.I will switch to Lunesta 3mg.
- I need advise, badly ckd!!
(Posted by a 49 year old woman who has Constipation, Peripheral Neuropathy, Orthostatic Hypotension, Chronic Kidney Disease, and takes Milk Thistle, Zolpidem, Melatonin, Xanax, Adderall 30, Zorvolex)
The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passe ...
Complete drug side effects:
On eHealthMe, Ambien (zolpidem tartrate) is often used to treat insomnia. Benadryl (diphenhydramine hydrochloride) is often used to treat allergen. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Ambien is used in:
- Benadryl is used in:
Other drugs that are used to treat the same conditions:
- Ambien alternatives:
- Benadryl alternatives:
Recent related drug studies (Check your drugs):
- A study of side effects of Zolpidem for a patient with Lupus. The patient has Insomnia (sleeplessness)
Comments: I have been diagnosed for 5 years. All my other issues are getting better except the insomnia. I dont know if I need more dosage or if its just not working.
- A study of side effects of Ambien for a patient with Sleep Disorder. The patient has Atrophy (wasting away of a part of the body)
Comments: I am currently weaning myself off of Ambien. Can Ambien cause moderate brain atrophy, dementia, or Alzheimer?
- A study of drug interactions between Norco, Benadryl Preservative Free for a patient with Migraine With Aura, Dystonia. The patient has Pain - Back, Headache, Chills
Comments: I didn't take the Norco today, but the benadryl I take every night.
- A study of drug interactions between Albuterol, Ibuprofen, Diphenhydramine Hydrochloride for a patient with Asthma, Migraines And Joint And Muscle Pain, Allergies. The patient has Aphasia
Comments: periodic/intermittent episodes of nominal aphasia. inability to recall names and words often used. sense of knowing the words but unable to retrieve them. episodes occur at random and vary in severity. no immediately obvious reasons nor any recent head traumas. rarely occurring moments where words d ...
- A study of drug interactions between Penicillin, Albuterol, Ambien, Zoloft, Propranolol Hydrochloride, Levothyroxine Thyroid for a patient with Otitis Externa, Asthma, Insomnia Related To Another Mental Condition, Anxiety Disorder Due To A General Medical Condition, Graves Disease. The patient has Pain - Shoulder, Neck Pain, Face Pain Around Ear, Neutropenia, Pressure-related Ear Pain, Ear Pain Both Sides, General Ill Feeling, Chills, Otitis Externa
Comments: A few years back I had medication induced neutropnia due to bactrim. I started getting symptoms in ear.. I had external otitis. I'm having the same symptoms
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.