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Review: Amitiza and Miralax

This review analyzes the effectiveness and drug interactions between Amitiza and Miralax. It is created by eHealthMe based on reports of 248 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Amitiza and Miralax >>>

What are the drugs

Amitiza (latest outcomes from 1,826 users) has active ingredients of lubiprostone. It is often used in constipation.

Miralax (latest outcomes from 9,260 users) has active ingredients of polyethylene glycol 3350. It is often used in constipation.

On Aug, 30, 2014: 248 people who take Amitiza, Miralax are studied

Amitiza, Miralax outcomes

Drug combinations in study:
- Amitiza (lubiprostone)
- Miralax (polyethylene glycol 3350)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amitiza is effective0.00%
(0 of 1 people)
(0 of 1 people)
(0 of 1 people)
(0 of 3 people)
Miralax is effectiven/a0.00%
(0 of 1 people)
(1 of 1 people)
(0 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaFallOedema PeripheralTardive DyskinesiaColonic Polypn/an/aPain
Drug IneffectiveFace InjuryAbdominal DistensionDrug IneffectiveConstipation
Abdominal PainBack InjuryHypoaesthesiaNauseaAnxiety
Muscle SpasmsMouth InjuryDrug IneffectiveDrug Effect DecreasedDyspnoea
DiarrhoeaRoad Traffic AccidentGastrointestinal DisorderTardive DyskinesiaAbdominal Pain
Chest PainOsteonecrosisHaematocheziaDiarrhoea
Chest DiscomfortOsteomyelitisMuscle SpasmsVomiting
Abdominal TendernessSpinal Cord DisorderRetchingPyrexia
Abdominal DistensionAnxietyVomitingFall

Drug effectiveness by gender :

Amitiza is effective0.00%
(0 of 3 people)
(0 of 3 people)
Miralax is effective50.00%
(1 of 2 people)
(0 of 3 people)

Most common drug interactions by gender * :

NauseaAbdominal Pain
Oedema PeripheralPain
Abdominal PainBlood Glucose Increased
CoughBack Pain
VomitingConfusional State
Abdominal Pain UpperDizziness

Drug effectiveness by age :

Amitiza is effectiven/an/a0.00%
(0 of 2 people)
(0 of 6 people)
(0 of 1 people)
(0 of 1 people)
Miralax is effectiven/an/a0.00%
(0 of 2 people)
(1 of 2 people)
(0 of 1 people)
(0 of 1 people)

Most common drug interactions by age * :

n/aChest DiscomfortVomitingPainCarcinoid Tumour Of The AppendixPainPainConstipation
Muscle SpasmsNauseaCholecystitis ChronicRenal CancerAnxietyAbdominal PainPain
Terminal InsomniaDiarrhoeaCholelithiasisGastric CancerDyspnoeaFallDrug Ineffective
Lactose IntoleranceAbdominal Pain UpperGallbladder DisorderConvulsionConstipationDiarrhoeaBack Pain
Chest PainGastrointestinal DisorderAbdominal Pain UpperConfusional StatePyrexiaConstipationVomiting
Drug IneffectiveCholecystitis ChronicChest PainHallucinationBone DisorderGastrooesophageal Reflux DiseaseDiarrhoea
NauseaBack PainPainful RespirationDrug Exposure During PregnancySwellingNauseaAsthenia
Frequent Bowel MovementsPainPulmonary EmbolismPregnancyOsteonecrosis Of JawAnxietyDizziness
Abdominal PainCholecystitisTachycardiaMyocardial InfarctionSinusitisPyrexiaChest Pain
AstheniaBlood Pressure DecreasedInjuryPalpitationsOsteomyelitisOedema PeripheralArthralgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amitiza and Miralax?

Can you answer these questions (what is this?):

  • Can i take ibuprofen when i'm on the medicine miralax to treat my massive head ache?
    I was recently told by a doctor that I was constipated and that I should take Miralax. I personally don't think I'm constipated. My lower abdomen hurts and so does my head. Every single time I sneeze or cough it hurts really bad! I want to know if I can take some ibuprofen to treat the pain. But I d ...

  • Can miralax cause hyperactivity?
    8 yr old female takes Miralax for constipation early evening and then gets hyperactive for short period of time. Is this related?

  • What has miralax done to my body? please help me...
    Years ago after multiple surgeries, I ended up with chronic constipation. GI doctor told me to take 4 doses of miralax everyday. About a year into the medication, I completely changed as a person. I experienced brain fog, anxiety, meltdowns, blowups, sexual dysfunction, and worst of all excessive ...

More questions for: Amitiza, Miralax

You may be interested at these reviews (what is this?):

  • Hair loss with miralax
    My hair started thinning out probably within a few weeks of starting Miralax on a daily basis. I continued taking it for approximately 6 months never thinking it was the Miralax. It being the only new drug I had been on, I looked on-line and immediately stopped taking it after seeing the side effect ...

  • Understanding and living with cancer
    After having one treatment of Gemzar, I had a sever reaction, which caused me to have many seizures. This caused me to developed PRES, which in turn has caused me to have brain damage.When I came out of my induced coma I did not know where I was, nor did I know who my family members were. I could no ...

  • Treating copd and kidney disease
    My biggest problem is trying to keep my blood pressure at 110 to 140 diastolic and controlling constipation.

More reviews for: Amitiza, Miralax

Complete drug side effects:

On eHealthMe, Amitiza (lubiprostone) is often used to treat constipation. Miralax (polyethylene glycol 3350) is often used to treat constipation. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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