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Review: taking Amitriptyline and Cymbalta together

Summary: drug interactions are reported among people who take Amitriptyline and Cymbalta together.

This review analyzes the effectiveness and drug interactions between Amitriptyline and Cymbalta. It is created by eHealthMe based on reports of 1,382 people who take the same drugs from FDA and social media, and is updated regularly.

 

You are not alone: join a support group for people who take Amitriptyline and Cymbalta >>>

On Mar, 8, 2015: 1,382 people who take Amitriptyline Hydrochloride, Cymbalta are studied

Amitriptyline Hydrochloride, Cymbalta outcomes

Drug combinations in study:
- Amitriptyline Hydrochloride (amitriptyline hydrochloride)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amitriptyline Hydrochloride is effective45.45%
(5 of 11 people)
14.29%
(2 of 14 people)
7.69%
(1 of 13 people)
23.81%
(5 of 21 people)
42.11%
(8 of 19 people)
22.22%
(2 of 9 people)
80.00%
(12 of 15 people)
0.00%
(0 of 1 people)
Cymbalta is effective0.00%
(0 of 8 people)
21.74%
(5 of 23 people)
16.67%
(3 of 18 people)
23.81%
(5 of 21 people)
21.74%
(5 of 23 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Drug effectiveness by gender :

FemaleMale
Amitriptyline Hydrochloride is effective35.90%
(28 of 78 people)
25.00%
(6 of 24 people)
Cymbalta is effective23.38%
(18 of 77 people)
16.67%
(4 of 24 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Amitriptyline Hydrochloride is effectiven/an/an/a8.33%
(3 of 36 people)
31.82%
(7 of 22 people)
18.75%
(9 of 48 people)
18.97%
(11 of 58 people)
17.86%
(5 of 28 people)
Cymbalta is effectiven/an/an/a2.78%
(1 of 36 people)
20.69%
(6 of 29 people)
8.16%
(4 of 49 people)
11.11%
(6 of 54 people)
17.86%
(5 of 28 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDizzinessBack PainInsomniaPainDepressionNauseaPain
FallFallDry MouthFatigueMigraineMalaiseMigraineNausea
Abdominal Pain UpperHeadacheHypertensionVomitingConstipationFluid RetentionConstipationAnxiety
AnxietyDrug IneffectiveMenorrhagiaConstipationType 2 Diabetes MellitusType 2 Diabetes MellitusChronic Tonsillar DiseaseFall
DiarrhoeaLoss Of ConsciousnessMeralgia ParaestheticaPainTremorCandidiasisItching ScarInsomnia
Renal FailureAspartate Aminotransferase IncreasedType 2 Diabetes MellitusLymphoedemaMuscle PainDeathSore ThroatFatigue
PruritusAlanine Aminotransferase IncreasedSleep Apnoea SyndromeHypoglycaemiaNauseaStaphylococcal InfectionPainful Red EyesHeadache
ConstipationTremorCarpal Tunnel SyndromeHyperglycaemiaInjuryNauseaEagles SyndromePyrexia
PainBlood Alkaline Phosphatase IncreasedFallMigraineDepressionCondition AggravatedTeeth GrindingArthralgia
RashPneumoniaPancreatitisShort-term Memory LossMemory ImpairmentPruritusDiscolored TeethDizziness

Most common drug interactions by gender * :

FemaleMale
PainFatigue
NauseaPain
InsomniaPneumonia
FallNausea
AnxietyAnxiety
ArthralgiaChest Pain
HeadacheType 2 Diabetes Mellitus
DiarrhoeaAsthenia
PyrexiaFall
DizzinessDepression

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes Mellitusn/aLocalised InfectionPainWeight IncreasedPainPainPain
Sensation Of Foreign BodyHypotensionFatigueDeathType 2 Diabetes MellitusAnxietyHeadache
Gallbladder OperationUrinary Tract InfectionAbdominal PainType 2 Diabetes MellitusNauseaNauseaAsthenia
Blood Cholesterol IncreasedDrug IneffectiveInsomniaDizzinessFallPyrexiaFatigue
Gastric UlcerAnxietyLoss Of ConsciousnessAbdominal Pain UpperFallPneumonia
Rectal HaemorrhageMuscle SpasmsInsomniaDiarrhoeaArthralgiaAnaemia
Feeling AbnormalSomnolenceSuicidal IdeationBack PainInsomniaOedema Peripheral
RashMemory ImpairmentAgitationDepressionInjuryWeight Decreased
AnxietyGait DisturbanceNauseaAnxietyDiarrhoeaOsteonecrosis Of Jaw
Erection IncreasedDepressionSomnolenceFatiguePain In JawChest Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amitriptyline and Cymbalta?

 

 

 

You are not alone! Join a related support group:
- support group for people who take Amitriptyline Hydrochloride
- support group for people who take Cymbalta

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used to treat migraine. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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