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Review: Amitriptyline and Cymbalta

This review analyzes the effectiveness and drug interactions between Amitriptyline and Cymbalta. It is created by eHealthMe based on reports of 1,380 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Amitriptyline and Cymbalta >>>

What are the drugs

Amitriptyline hydrochloride (latest outcomes from 7,123 users) has active ingredients of amitriptyline hydrochloride. It is often used in migraine.

Cymbalta (latest outcomes from 49,215 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

On Oct, 29, 2014: 1,380 people who take Amitriptyline Hydrochloride, Cymbalta are studied

Amitriptyline Hydrochloride, Cymbalta outcomes

Drug combinations in study:
- Amitriptyline Hydrochloride (amitriptyline hydrochloride)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amitriptyline Hydrochloride is effective45.45%
(5 of 11 people)
14.29%
(2 of 14 people)
7.69%
(1 of 13 people)
21.05%
(4 of 19 people)
42.11%
(8 of 19 people)
22.22%
(2 of 9 people)
80.00%
(12 of 15 people)
0.00%
(0 of 1 people)
Cymbalta is effective0.00%
(0 of 8 people)
21.74%
(5 of 23 people)
16.67%
(3 of 18 people)
20.00%
(4 of 20 people)
18.18%
(4 of 22 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDizzinessBack PainInsomniaPainDepressionNauseaPain
FallFallDry MouthFatigueMigraineMalaiseMigraineNausea
Abdominal Pain UpperHeadacheHypertensionPainType 2 Diabetes MellitusFluid RetentionConstipationAnxiety
AnxietyDrug IneffectiveMenorrhagiaVomitingTremorType 2 Diabetes MellitusChronic Tonsillar DiseaseFall
DiarrhoeaLoss Of ConsciousnessMeralgia ParaestheticaMigraineEpilepsyCandidiasisItching ScarInsomnia
Renal FailureAspartate Aminotransferase IncreasedType 2 Diabetes MellitusMental Status ChangesFatigueDeathSore ThroatFatigue
PruritusAlanine Aminotransferase IncreasedSleep Apnoea SyndromeLymphoedemaNauseaStaphylococcal InfectionPainful Red EyesHeadache
ConstipationTremorCarpal Tunnel SyndromeNeuropathy PeripheralMemory ImpairmentNauseaEagles SyndromePyrexia
PainBlood Alkaline Phosphatase IncreasedFallSkin CandidaSuicidal IdeationCondition AggravatedTeeth GrindingArthralgia
RashPneumoniaPancreatitisObesityConstipationPruritusDiscolored TeethDizziness

Drug effectiveness by gender :

FemaleMale
Amitriptyline Hydrochloride is effective36.36%
(28 of 77 people)
21.74%
(5 of 23 people)
Cymbalta is effective22.37%
(17 of 76 people)
13.04%
(3 of 23 people)

Most common drug interactions by gender * :

FemaleMale
PainFatigue
NauseaPain
InsomniaPneumonia
FallNausea
AnxietyAnxiety
ArthralgiaChest Pain
HeadacheType 2 Diabetes Mellitus
PyrexiaAsthenia
DiarrhoeaFall
DizzinessDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Amitriptyline Hydrochloride is effectiven/an/an/a8.33%
(3 of 36 people)
31.82%
(7 of 22 people)
18.75%
(9 of 48 people)
19.61%
(10 of 51 people)
19.23%
(5 of 26 people)
Cymbalta is effectiven/an/an/a2.78%
(1 of 36 people)
20.69%
(6 of 29 people)
8.16%
(4 of 49 people)
10.64%
(5 of 47 people)
15.38%
(4 of 26 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes Mellitusn/aLocalised InfectionPainWeight IncreasedPainPainPain
Sensation Of Foreign BodyHypotensionFatigueDeathType 2 Diabetes MellitusAnxietyHeadache
Gallbladder OperationUrinary Tract InfectionAbdominal PainType 2 Diabetes MellitusNauseaNauseaAsthenia
Blood Cholesterol IncreasedDrug IneffectiveInsomniaDizzinessFallPyrexiaFatigue
Gastric UlcerAnxietyLoss Of ConsciousnessAbdominal Pain UpperFallPneumonia
Rectal HaemorrhageMuscle SpasmsInsomniaDiarrhoeaArthralgiaAnaemia
Feeling AbnormalSomnolenceSuicidal IdeationBack PainInsomniaOedema Peripheral
RashMemory ImpairmentAgitationDepressionInjuryWeight Decreased
AnxietyGait DisturbanceNauseaAnxietyDiarrhoeaOsteonecrosis Of Jaw
Erection IncreasedDepressionSomnolenceFatiguePain In JawChest Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amitriptyline and Cymbalta?

Get connected! Join a related mobile support group:
- support group for people who take Amitriptyline and Cymbalta
- support group for people who take Amitriptyline Hydrochloride
- support group for people who take Cymbalta

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Complete drug side effects:

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used to treat migraine. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies:

More related studies for: Amitriptyline Hydrochloride, Cymbalta

Recent related drug comparison:

More related comparisons for: Amitriptyline Hydrochloride, Cymbalta

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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