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Review: Amitriptyline and Cymbalta

This review analyzes the effectiveness and drug interactions between Amitriptyline and Cymbalta. It is created by eHealthMe based on reports of 1,378 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Amitriptyline and Cymbalta >>>

What are the drugs

Amitriptyline hydrochloride (latest outcomes from 7,085 users) has active ingredients of amitriptyline hydrochloride. It is used in migraine.

Cymbalta (latest outcomes from 49,154 users) has active ingredients of duloxetine hydrochloride. It is used in depression.

On Aug, 16, 2014: 1,378 people who take Amitriptyline Hydrochloride, Cymbalta are studied

Amitriptyline Hydrochloride, Cymbalta outcomes

Drug combinations in study:
- Amitriptyline Hydrochloride (amitriptyline hydrochloride)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amitriptyline Hydrochloride is effective45.45%
(5 of 11 people)
14.29%
(2 of 14 people)
8.33%
(1 of 12 people)
21.05%
(4 of 19 people)
44.44%
(8 of 18 people)
22.22%
(2 of 9 people)
80.00%
(12 of 15 people)
0.00%
(0 of 1 people)
Cymbalta is effective0.00%
(0 of 8 people)
21.74%
(5 of 23 people)
17.65%
(3 of 17 people)
21.05%
(4 of 19 people)
19.05%
(4 of 21 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDizzinessBack PainInsomniaPainDepressionNauseaPain
FallFallDry MouthFatigueMigraineMalaiseMigraineNausea
Abdominal Pain UpperHeadacheHypertensionPainType 2 Diabetes MellitusFluid RetentionConstipationAnxiety
AnxietyDrug IneffectiveMenorrhagiaVomitingTremorType 2 Diabetes MellitusChronic Tonsillar DiseaseFall
DiarrhoeaLoss Of ConsciousnessMeralgia ParaestheticaMigraineSuicidal IdeationCandidiasisItching ScarInsomnia
Renal FailureAspartate Aminotransferase IncreasedType 2 Diabetes MellitusMental Status ChangesConstipationDeathSore ThroatFatigue
PruritusAlanine Aminotransferase IncreasedSleep Apnoea SyndromeLymphoedemaNauseaStaphylococcal InfectionPainful Red EyesHeadache
ConstipationTremorCarpal Tunnel SyndromeNeuropathy PeripheralFatigueNauseaEagles SyndromePyrexia
PainBlood Alkaline Phosphatase IncreasedFallSkin CandidaEpilepsyCondition AggravatedTeeth GrindingArthralgia
RashPneumoniaPancreatitisObesityVision BlurredPruritusDiscolored TeethDizziness

Drug effectiveness by gender :

FemaleMale
Amitriptyline Hydrochloride is effective36.36%
(28 of 77 people)
23.81%
(5 of 21 people)
Cymbalta is effective22.37%
(17 of 76 people)
14.29%
(3 of 21 people)

Most common drug interactions by gender * :

FemaleMale
PainFatigue
NauseaPain
InsomniaPneumonia
FallNausea
AnxietyAnxiety
ArthralgiaChest Pain
HeadacheType 2 Diabetes Mellitus
PyrexiaAsthenia
DiarrhoeaFall
DizzinessDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Amitriptyline Hydrochloride is effectiven/an/an/a8.33%
(3 of 36 people)
31.82%
(7 of 22 people)
18.75%
(9 of 48 people)
19.61%
(10 of 51 people)
21.74%
(5 of 23 people)
Cymbalta is effectiven/an/an/a2.78%
(1 of 36 people)
20.69%
(6 of 29 people)
8.16%
(4 of 49 people)
10.64%
(5 of 47 people)
18.18%
(4 of 22 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes Mellitusn/aLocalised InfectionPainWeight IncreasedPainPainPain
Sensation Of Foreign BodyHypotensionFatigueDeathType 2 Diabetes MellitusAnxietyHeadache
Gallbladder OperationUrinary Tract InfectionAbdominal PainType 2 Diabetes MellitusNauseaNauseaAsthenia
Blood Cholesterol IncreasedDrug IneffectiveInsomniaDizzinessFallPyrexiaFatigue
Gastric UlcerAnxietyLoss Of ConsciousnessAbdominal Pain UpperFallPneumonia
Rectal HaemorrhageMuscle SpasmsInsomniaDiarrhoeaArthralgiaAnaemia
Feeling AbnormalSomnolenceSuicidal IdeationBack PainInsomniaWeight Decreased
RashMemory ImpairmentAgitationDepressionInjuryOedema Peripheral
AnxietyGait DisturbanceNauseaAnxietyDiarrhoeaOsteonecrosis Of Jaw
Erection IncreasedDepressionSomnolenceFatiguePain In JawChest Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Amitriptyline and Cymbalta
- group for people who take Amitriptyline Hydrochloride
- group for people who take Cymbalta

Comments from related studies:

  • From this study (4 days ago):

  • He is a cancer patient with bowel cancer.he needs the medication because his tumour is hitting off his nerves

    Reply

  • From this study (3 months ago):

  • Occurs periodically usually a short time after food

    Reply

  • From this study (4 months ago):

  • 3 weeks on Amitriptyline and currently experiencing a migraine for 3 days now.
    Had root canal two weeks ago; percocets for pain following that, but not in past 5-7 days. Still have residual pain in jaw and along jawline up to ear from that. Have been taking Cymbalta for 2+ months with great results.

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used to treat migraine. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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