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Home > Amitriptyline > Wellbutrin > Amitriptyline and Wellbutrin

Review: Amitriptyline and Wellbutrin

This review analyzes the effectiveness and drug interactions between Amitriptyline and Wellbutrin. It is created by eHealthMe based on reports of 1,475 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Amitriptyline and Wellbutrin >>>

What are the drugs

Amitriptyline hydrochloride (latest outcomes from 7,133 users) has active ingredients of amitriptyline hydrochloride. It is often used in depression.

Trend of amitriptyline hydrochloride reports

Wellbutrin (latest outcomes from 54,933 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

Trend of wellbutrin reports

On Nov, 13, 2014: 1,475 people who take Amitriptyline Hydrochloride, Wellbutrin are studied

Amitriptyline Hydrochloride, Wellbutrin outcomes

Drug combinations in study:
- Amitriptyline Hydrochloride (amitriptyline hydrochloride)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amitriptyline Hydrochloride is effective20.00%
(2 of 10 people)
(5 of 20 people)
(2 of 8 people)
(9 of 19 people)
(6 of 14 people)
(6 of 17 people)
(0 of 2 people)
(0 of 1 people)
Wellbutrin is effective22.22%
(2 of 9 people)
(2 of 15 people)
(5 of 17 people)
(4 of 15 people)
(8 of 24 people)
(9 of 14 people)
(2 of 4 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveDepressionType 2 Diabetes MellitusGastrooesophageal Reflux DiseaseDiabetic NeuropathyDepressionInsomniaDepression
AnxietyNauseaMultiple AllergiesDepressionDiabetes Mellitus Inadequate ControlAnxietyDepressionPain
InsomniaAnxietyMuscle SpasmsFatigueDepressionLoss Of ConsciousnessExhaustion, Fatigue, Lethargy, Tiredness, WearinessAnxiety
AgitationSuicide AttemptHyperlipidaemiaNauseaWeight IncreasedAggressionPtsdNausea
AmnesiaHeadacheDiabetic NeuropathyConstipationBlood Glucose IncreasedBipolar DisorderInsomnia NecArthralgia
AggressionAnorexiaHypercholesterolaemiaBacteraemiaDiabetic RetinopathySuicidal IdeationAnxiety NecBack Pain
ConvulsionSuicidal IdeationNauseaDiarrhoeaProteinuriaWeight GainObesityFatigue
Feeling AbnormalHeart Rate IrregularBlood Cholesterol IncreasedCardio-respiratory ArrestBlood Triglycerides IncreasedIntentional OverdoseWeight IncreasedWeight Increased
DyskinesiaSupraventricular ExtrasystolesSciaticaComaRenal DisorderSuicide AttemptHyperglycaemiaHeadache
Respiratory Tract InfectionVentricular ExtrasystolesBack PainHypertensionType 2 Diabetes MellitusCognitive DisorderTardive DyskinesiaFall

Drug effectiveness by gender :

Amitriptyline Hydrochloride is effective33.33%
(23 of 69 people)
(7 of 22 people)
Wellbutrin is effective35.62%
(26 of 73 people)
(7 of 25 people)

Most common drug interactions by gender * :

Weight IncreasedDizziness
FatigueBack Pain
DiarrhoeaMusculoskeletal Pain
HeadacheWeight Decreased
FallAtrial Fibrillation

Drug effectiveness by age :

Amitriptyline Hydrochloride is effectiven/an/a100.00%
(1 of 1 people)
(4 of 31 people)
(6 of 55 people)
(9 of 77 people)
(9 of 37 people)
(1 of 6 people)
Wellbutrin is effectiven/an/a50.00%
(1 of 2 people)
(10 of 36 people)
(5 of 63 people)
(9 of 78 people)
(7 of 41 people)
(1 of 6 people)

Most common drug interactions by age * :

Diabetes MellitusSudden DeathCompleted SuicideDepressionWeight IncreasedDepressionPainDepression
DeathHeadachePain In ExtremityDepressionPainAnxietyNausea
AggressionMuscle SpasmsDyspnoeaAnxietyArthralgiaFatigue
SyncopeConstipationBack PainBack PainNauseaAnxiety
NauseaHypoaesthesiaType 2 Diabetes MellitusHyperhidrosisFallFall
InsomniaAnxietyFatigueChest PainDiarrhoeaCardiac Failure Congestive
Memory ImpairmentDrug IneffectiveDizzinessType 2 Diabetes MellitusDepressionConfusional State
AgitationCellulitisSuicidal IdeationAstheniaHeadachePain
RashLoss Of ConsciousnessAnxietyFallAnaemiaPneumonia
Rectal HaemorrhageBipolar Ii DisorderNauseaDiabetes MellitusConstipationSyncope

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amitriptyline and Wellbutrin?

You are not alone! Join a related mobile support group:
- support group for people who take Amitriptyline and Wellbutrin
- support group for people who take Amitriptyline Hydrochloride
- support group for people who take Wellbutrin

Can you answer these questions (Ask a question):

More questions for: Amitriptyline Hydrochloride, Wellbutrin

You may be interested at these reviews (Write a review):

  • Bedwetting with paxil and wellbutrin
    (Posted by a 38 year old man who has Bedwetting, and takes Wellbutrin Xl, Paxil)
    I have been using both of these drugs and now have bedwetting issues 5 times a week on average. I would rate the bedwetting as moderate about a6/10 but my wife and I can live with this as she had made the comment " you are back to the man I married ". I started taking these due to depression about ...

  • Wellbutrin caused my trigeminal neurlagia
    (Posted by a 25 year old man who has Trigeminal Neuralgia, and takes Wellbutrin)
    So I'm writing this to hopefully shed light to other users in the same position I was in. I had taken Wellbutrin for about 4 years. The pain experienced in my face was excruciatingly painful. It was just on one side of my face between my temple and upper lip. All the symptoms reflected Trigeminal Ne ...

  • Lorazepam nearly killed me during cancer treatment
    (Posted by a 66 year old woman who has Insomnia, Bowel Movement Irregularity, Withdrawal Syndrome, and takes Wellbutrin Sr, Prozac, Lorazepam)
    Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first ...

  • Chills associated with ibuprophen
    (Posted by a 69 year old man who has Persistent Chills., and takes Desloratadine, Celexa, Codeine, Fiorinal W/codeine, Cialis, Proscar, Flomax, Wellbutrin)
    I generally respond well to medication. I am a senior who has chronic pain from a c1-c2 fusion. Codeine works well, and I don't use a lot. Still, I sought alternatives to opiates for nerve pain. I lice in a colder climate. It took me quite a while to associate susceptibility to becoming chilled w ...

  • Androgel for secondary hypogonadism
    (Posted by a 55 year old man who has Swelling Of The Ankles - Feet - Legs, and takes Simvastatin, Cetirizine Hydrochloride Allergy, Amitriptyline Hydrochloride, Venlafaxine Hydrochloride, Morphine Sulfate, Amlodipine Besylate)
    Severe swelling in legs, ankles and feet after being on my feet for more than one hour. Pain in calves and ankles. Feels like they're being squeezed or compressed. Pain dissipates after laying down for a few hours. Swelling never completely dissipates. Always some swelling in ankles.

More reviews for: Amitriptyline Hydrochloride, Wellbutrin

Complete drug side effects:

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used to treat depression. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Amitriptyline Hydrochloride, Wellbutrin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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