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Review: Amlodipine and Simvastatin

This review analyzes the effectiveness and drug interactions between Amlodipine and Simvastatin. It is created by eHealthMe based on reports of 10,403 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Amlodipine and Simvastatin >>>

What are the drugs

Amlodipine (latest outcomes from 46,515 users) has active ingredients of amlodipine besylate. It is often used in high blood pressure.

Simvastatin (latest outcomes from 80,771 users) has active ingredients of simvastatin. It is often used in high blood cholesterol.

On Oct, 25, 2014: 10,403 people who take Amlodipine, Simvastatin are studied

Amlodipine, Simvastatin outcomes

Drug combinations in study:
- Amlodipine (amlodipine besylate)
- Simvastatin (simvastatin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amlodipine is effective12.50%
(1 of 8 people)
31.58%
(12 of 38 people)
32.26%
(10 of 31 people)
36.96%
(17 of 46 people)
53.85%
(35 of 65 people)
57.50%
(23 of 40 people)
61.11%
(11 of 18 people)
n/a
Simvastatin is effective14.29%
(1 of 7 people)
29.63%
(8 of 27 people)
23.08%
(6 of 26 people)
35.56%
(16 of 45 people)
52.38%
(33 of 63 people)
61.70%
(29 of 47 people)
80.95%
(17 of 21 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaRhabdomyolysisMyalgiaRhabdomyolysisHypertensionAnxietyIntervertebral Disc ProtrusionNausea
FatigueRenal FailureAnxietyDyspnoeaMyalgiaPainInjuryDyspnoea
Renal FailureGastrointestinal HaemorrhageHypertensionDizzinessDepressionDyspnoeaWeight DecreasedPain
MyalgiaDizzinessChest PainChest PainAstheniaRhabdomyolysisBlood Cholesterol IncreasedFatigue
RhabdomyolysisOedema PeripheralDiabetes MellitusAstheniaMyocardial InfarctionCerebrovascular AccidentInfectionChest Pain
Blood Creatine Phosphokinase IncreasedMyalgiaInsomniaAnxietyInsomniaMyocardial InfarctionDepressionAnxiety
PalpitationsColitisAstheniaPain In ExtremityArthralgiaCardiac Failure CongestiveSciaticaAsthenia
DizzinessPancreatitisSkin UlcerMyalgiaPainDepressionFatigueDizziness
Coronary Artery DiseaseDiarrhoeaAmnesiaRenal Failure AcuteCardiac Failure CongestiveNephrogenic Systemic FibrosisDrug IneffectiveMyocardial Infarction
Chest DiscomfortMyopathyConstipationDepressionMuscle AtrophyEmotional DistressIntervertebral Disc DisorderOedema Peripheral

Drug effectiveness by gender :

FemaleMale
Amlodipine is effective44.23%
(46 of 104 people)
44.37%
(63 of 142 people)
Simvastatin is effective39.58%
(38 of 96 people)
51.43%
(72 of 140 people)

Most common drug interactions by gender * :

FemaleMale
NauseaDyspnoea
PainPain
DyspnoeaChest Pain
FatigueMyocardial Infarction
FallCardiac Failure Congestive
AnxietyAsthenia
Oedema PeripheralAnxiety
DizzinessRenal Failure
AstheniaDizziness
Chest PainRenal Failure Acute

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Amlodipine is effectiven/an/an/a50.00%
(1 of 2 people)
17.86%
(5 of 28 people)
31.71%
(13 of 41 people)
22.39%
(15 of 67 people)
30.12%
(75 of 249 people)
Simvastatin is effectiven/an/an/a0.00%
(0 of 2 people)
12.50%
(3 of 24 people)
44.83%
(13 of 29 people)
27.69%
(18 of 65 people)
31.40%
(76 of 242 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
PneumoniaFaeces DiscolouredOsteoporosis NosHypotensionBlood Cholesterol IncreasedAnxietyNauseaDyspnoea
Renal ImpairmentDuodenal Ulcer HaemorrhageLymphangiomaAstheniaHypertensionPainPainNausea
InfectionDiarrhoeaBack PainDehydrationInsomniaDyspnoeaMyocardial InfarctionPain
PallorLoss Of ConsciousnessPyrexiaBlood Creatinine IncreasedCoughNauseaChest PainFatigue
HyperhidrosisGastrointestinal HaemorrhageHypertensive CrisisAbdominal PainDizzinessChest PainAnxietyAsthenia
Mitral Valve IncompetenceSyncopeVentricular HypertrophyGastrointestinal DisorderAngina PectorisDepressionRenal FailureFall
Haemoglobin DecreasedPruritus NosDehydrationPeritonitisSleep Apnoea SyndromeFatigueDyspnoeaDizziness
Fluid OverloadPurpura NosAlopeciaPharyngeal HaemorrhageCardiac Failure CongestiveDizzinessAstheniaChest Pain
Haematocrit DecreasedPallorHigh Turnover OsteopathyPulmonary CongestionDepressionMyocardial InfarctionDepressionRenal Failure
Pitting OedemaPancreatitis NosSkin NoduleHaemorrhageAbdominal Pain UpperPain In ExtremityFatigueRenal Failure Acute

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amlodipine and Simvastatin?

Get connected! Join a related mobile support group:
- support group for people who take Amlodipine and Simvastatin
- support group for people who take Amlodipine
- support group for people who take Simvastatin

Comments from related studies:

  • From this study (1 month ago):

  • Vicky on Sep, 23, 2014:

    Accidentally discovered severe joint swelling as a reaction to Novolog during a pump vacation. Been on an insulin pump for 30 years.

    Female, 56

    Reply

  • From this study (2 months ago):

  • Hair thinning started after take Metformin a year ago.

    Reply

  • From this study (3 months ago):

  • I am concerned that my serotonin levels are dropping due to Amlodipine Besylate and Simvastatin. I have taken Lexapro (Escitalopram Oxalate),
    Paxil (Paroxetine Hydrochloride, Prozac (Fluoxetine Hcl) in the past, not all at once and am considering returning to a serotonin reuptake inhibitors to reduce the constant agitation that I am experiencing.

    Reply

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Complete drug side effects:

On eHealthMe, Amlodipine (amlodipine besylate) is often used to treat high blood pressure. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

 

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