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Review: Amlodipine and Simvastatin

This review analyzes the effectiveness and drug interactions between Amlodipine and Simvastatin. It is created by eHealthMe based on reports of 10,401 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Amlodipine (what 46,480 Amlodipine users reported?) has active ingredients of amlodipine besylate. It is used in high blood pressure.

Simvastatin (what 80,744 Simvastatin users reported?) has active ingredients of simvastatin. It is used in high blood cholesterol.

On Sep, 15, 2014: 10,401 people who take Amlodipine, Simvastatin are studied

Amlodipine, Simvastatin outcomes

Drug combinations in study:
- Amlodipine (amlodipine besylate)
- Simvastatin (simvastatin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amlodipine is effective12.50%
(1 of 8 people)
31.58%
(12 of 38 people)
32.26%
(10 of 31 people)
36.96%
(17 of 46 people)
53.12%
(34 of 64 people)
57.50%
(23 of 40 people)
61.11%
(11 of 18 people)
n/a
Simvastatin is effective14.29%
(1 of 7 people)
29.63%
(8 of 27 people)
23.08%
(6 of 26 people)
35.56%
(16 of 45 people)
52.38%
(33 of 63 people)
60.87%
(28 of 46 people)
80.95%
(17 of 21 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaRhabdomyolysisMyalgiaRhabdomyolysisHypertensionAnxietyIntervertebral Disc ProtrusionNausea
FatigueRenal FailureAnxietyDyspnoeaMyalgiaPainInjuryDyspnoea
Renal FailureGastrointestinal HaemorrhageHypertensionDizzinessAstheniaDyspnoeaWeight DecreasedPain
MyalgiaDizzinessChest PainChest PainDepressionCerebrovascular AccidentBlood Cholesterol IncreasedFatigue
RhabdomyolysisOedema PeripheralDiabetes MellitusAstheniaMyocardial InfarctionMyocardial InfarctionInfectionChest Pain
Blood Creatine Phosphokinase IncreasedMyalgiaInsomniaAnxietyPainRhabdomyolysisDepressionAsthenia
PalpitationsColitisAstheniaPain In ExtremityArthralgiaDepressionSciaticaAnxiety
DizzinessPancreatitisSkin UlcerMyalgiaInsomniaCardiac Failure CongestiveFatigueDizziness
Coronary Artery DiseaseDiarrhoeaAmnesiaRenal Failure AcuteCerebrovascular AccidentEmotional DistressDrug IneffectiveMyocardial Infarction
Chest DiscomfortMyopathyConstipationDepressionMuscle AtrophyGeneral Physical Health DeteriorationIntervertebral Disc DisorderOedema Peripheral

Drug effectiveness by gender :

FemaleMale
Amlodipine is effective44.23%
(46 of 104 people)
43.97%
(62 of 141 people)
Simvastatin is effective39.58%
(38 of 96 people)
51.08%
(71 of 139 people)

Most common drug interactions by gender * :

FemaleMale
NauseaDyspnoea
PainPain
DyspnoeaChest Pain
FatigueMyocardial Infarction
FallCardiac Failure Congestive
AnxietyAsthenia
Oedema PeripheralRenal Failure
DizzinessAnxiety
AstheniaDizziness
Chest PainRenal Failure Acute

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Amlodipine is effectiven/an/an/a50.00%
(1 of 2 people)
17.86%
(5 of 28 people)
32.43%
(12 of 37 people)
22.39%
(15 of 67 people)
30.12%
(75 of 249 people)
Simvastatin is effectiven/an/an/a0.00%
(0 of 2 people)
12.50%
(3 of 24 people)
48.00%
(12 of 25 people)
27.69%
(18 of 65 people)
31.40%
(76 of 242 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
PneumoniaFaeces DiscolouredOsteoporosis NosHypotensionBlood Cholesterol IncreasedAnxietyNauseaDyspnoea
Renal ImpairmentDuodenal Ulcer HaemorrhageLymphangiomaAstheniaHypertensionPainPainNausea
InfectionDiarrhoeaBack PainDehydrationInsomniaDyspnoeaMyocardial InfarctionPain
PallorLoss Of ConsciousnessPyrexiaBlood Creatinine IncreasedCoughNauseaChest PainFatigue
HyperhidrosisGastrointestinal HaemorrhageHypertensive CrisisAbdominal PainDizzinessChest PainAnxietyAsthenia
Mitral Valve IncompetenceSyncopeVentricular HypertrophyGastrointestinal DisorderAngina PectorisDepressionRenal FailureFall
Haemoglobin DecreasedPruritus NosDehydrationPeritonitisSleep Apnoea SyndromeFatigueDyspnoeaDizziness
Fluid OverloadPurpura NosAlopeciaPharyngeal HaemorrhageCardiac Failure CongestiveDizzinessAstheniaChest Pain
Haematocrit DecreasedPallorHigh Turnover OsteopathyPulmonary CongestionDepressionMyocardial InfarctionDepressionRenal Failure
Pitting OedemaPancreatitis NosSkin NoduleHaemorrhageAbdominal Pain UpperPain In ExtremityFatigueRenal Failure Acute

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amlodipine and Simvastatin?

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Comments from related studies:

  • From this study (3 weeks ago):

  • Hair thinning started after take Metformin a year ago.

    Reply

  • From this study (1 month ago):

  • I am concerned that my serotonin levels are dropping due to Amlodipine Besylate and Simvastatin. I have taken Lexapro (Escitalopram Oxalate),
    Paxil (Paroxetine Hydrochloride, Prozac (Fluoxetine Hcl) in the past, not all at once and am considering returning to a serotonin reuptake inhibitors to reduce the constant agitation that I am experiencing.

    Reply

  • From this study (2 months ago):

  • Stage 4 CKD and Stage 3 Heart Diease

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Amlodipine (amlodipine besylate) is often used to treat high blood pressure. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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