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Review: Amlodipine and Simvastatin

This review analyzes the effectiveness and drug interactions between Amlodipine and Simvastatin. It is created by eHealthMe based on 10,162 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 5, 2014: 10,162 people who reported to have interactions when taking Amlodipine, Simvastatin are studied

Trend of Amlodipine, Simvastatin's drug interactions, side effects and effectiveness reports (9250774)

Drug combinations in study:
- Amlodipine (amlodipine besylate)
- Simvastatin (simvastatin)

eHealthMe real world results:

Most common interactions experienced by people in the use of Amlodipine, Simvastatin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)2,679
Anxiety2,472
Asthenia (weakness)2,273
Pain1,927
Renal Failure (kidney dysfunction)1,913
Diarrhoea1,811
Nausea (feeling of having an urge to vomit)1,693
Fatigue (feeling of tiredness)1,471
Chest Pain1,451
Dizziness1,380

Most common interactions experienced by people in long term use of Amlodipine, Simvastatin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Asthenia (weakness)213
Anxiety210
Myalgia (muscle pain)171
Dyspnoea (difficult or laboured respiration)151
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)140
Pain130
Depression110
Chest Pain106
General Physical Health Deterioration (weak health status)92
Pain In Extremity90

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Amlodipine2.78%19.44%31.94%37.50%8.33%
Simvastatin0.00%12.00%38.00%46.00%4.00%

Top conditions involved for these people * :

  1. Hypertension
  2. Diabetes mellitus
  3. Blood cholesterol increased
  4. Depression
  5. Type 2 diabetes mellitus

Top co-used drugs for these people * :

  1. Norvasc
  2. Zocor
  3. Aspirin
  4. Lisinopril
  5. Lasix

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Amlodipine, Simvastatin

You can also:

Complete drug side effects:

On eHealthMe, Amlodipine (amlodipine besylate) is often used to treat high blood pressure. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 weeks ago):

  • BECAUSE OF A STROKE I EXPERIENCED AUGUST 5, 2010, I AM UNCOMFORTABLE IN MY OWN SKIN 24/7 ADD THE DISCOMFORTS CREATED FROM THE MEDICINE I TAKE SOME DAYS ARE HARDER TO STAY POSITIVE ABOUT MY LIFE. I HAVE A LOT OF STRESS DAILY AND TRYING TO FIGURE OUT HOW TO ACHIEVE SOME LEVEL OF COMFORT AND I SEEM TO BE FAILING AND I FEEL ITS DUE TO THE COMBINATION OF THE MEDICINES I TAKE.

    Reply

  • From this study (1 month ago):

  • Believe my problem is with Formoterol. Symptoms (breathlessness and being winded with minimal exertion) first noted three years ago after taking Foradil aerolizer (formoterol) and asmanex twisthaler for one to two years. Health, stamina gradually dimished to shortness of breath with minimal exertion. One - two years ago prescription changed to symbicort. health improved dramatically for approximately two months. Began walking one to two miles a day. Now back to being winded with minimal exertion. Health seems better until I take my symbicort. Spiriva seems to counter act breathlessness at morning when I take with symbicort. At evening with no Spiriva, breathlessness prevails. using Spiriva twice daily works but doctor says no.

    Reply

  • From this study (3 months ago):

  • While I had the flu I began using guaifenesin and Sudafed to try to relieve the symptoms of sinus discharge, post-nasal drip and phlegm, and cough. I have mostly recovered but still cough a lot due to excessive sinus drainage and phlegm in my lungs.

    Reply

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Can you answer these questions (what is this?):

More questions for: Amlodipine, Simvastatin

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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