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Review: Amlodipine Besylate and Metformin

This review analyzes the effectiveness and drug interactions between Amlodipine Besylate and Metformin. It is created by eHealthMe based on 7,704 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 2, 2014: 7,704 people who reported to have interactions when taking Amlodipine Besylate, Metformin are studied

Trend of Amlodipine Besylate, Metformin's drug interactions, side effects and effectiveness reports (4116881)

Drug combinations in study:
- Amlodipine Besylate (amlodipine besylate)
- Metformin (metformin hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Amlodipine Besylate, Metformin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)1,878
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)1,509
Nausea (feeling of having an urge to vomit)1,394
Diarrhoea1,321
Pain1,250
Fatigue (feeling of tiredness)1,099
Blood Glucose Increased992
Cardiac Failure Congestive954
Renal Failure Acute (rapid kidney dysfunction)948
Oedema Peripheral (superficial swelling)816

Most common interactions experienced by people in long term use of Amlodipine Besylate, Metformin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety88
Pain62
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)57
Dyspnoea (difficult or laboured respiration)55
Lactic Acidosis (low ph in body tissues)48
Dizziness47
Injury46
Renal Failure Acute (rapid kidney dysfunction)44
Emotional Distress40
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)32

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Amlodipine Besylate2.27%6.82%63.64%15.91%11.36%
Metformin4.65%23.26%37.21%23.26%11.63%

Top conditions involved for these people * :

  1. Hypertension
  2. Diabetes mellitus
  3. Type 2 diabetes mellitus
  4. Pain
  5. Rheumatoid arthritis

Top co-used drugs for these people * :

  1. Norvasc
  2. Glucophage
  3. Aspirin
  4. Lipitor
  5. Lisinopril

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Amlodipine Besylate, Metformin

You can also:

Complete drug side effects:

On eHealthMe, Amlodipine Besylate (amlodipine besylate) is often used to treat high blood pressure. Metformin (metformin hydrochloride) is often used to treat type 2 diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 day ago):

  • Recently Dxd w/ toxic multinodular goiter/hyperthyroidism. Fibromyalgia for 20+ years. Had to titrate off Savella 100 mg. BID due to hyperthyroidism. Now all above symptoms have worsened. Because thyroid blood work was in normal range ( although I had been on low iodine diet for 2 months, which should keep in normal range) endocrinologist said see me in six months! No instructions, no explanations. Can't find much about Plummer's online! Had bad reaction during uptake scan & ER said due to RAI. If levels had been high on blood work following scan results, Dr wanted to do RAI Ablation. I am a.) Afraid of worse reaction; b.) Ablation not working, having to be repeated; c.) Ultimately having to have thyroid removed surgically.
    I need to know my options! What should I be doing now? Anger and aggression, plus crying all the time are taking over my life. Savella was like a miracle drug for my fibromyalgia, but since it was an SNRI I am wondering how much of my problems is from stopping that. I did titrate off professionally, but had been on it over 3 years. Also wondering if it, hyperthyroidism or both are reason I am on four bp meds as cardiologist says heart is healthy. No history of stroke or seizures.
    Is there anyone out there who can give me direction? Every day is worse. Also having injections in c- spine to determine if neurological surgery w/ help w/ spinal cord compression. First was done Monday.
    Eyes also not focusing! Fibromyalgia or hyperthyroidism? Dr says I have 20/20 in each eye individually & field vision test okay. Still can't see TV or anything up close such as cosmetic needs for face! Nothing helps close vision. Glasses will help distance clear enough for now.

    Reply

  • From this study (1 week ago):

  • After taking medications in morning I feel dizzy and light headed and can't do anything. Also very tired all the time

    Reply

  • From this study (1 month ago):

  • have been very depressed for at least two years. Taking wellbutrin, and prozac for depression for the last month.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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