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Review: taking Baclofen and Benadryl together

Summary: drug interactions are reported among people who take Baclofen and Benadryl together.

This review analyzes the effectiveness and drug interactions between Baclofen and Benadryl. It is created by eHealthMe based on reports of 408 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Baclofen and Benadryl >>>

What are the drugs

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. (latest outcomes from 21,207 Baclofen users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,395 Benadryl users)

On Feb, 13, 2015: 408 people who take Baclofen, Benadryl are studied

Baclofen, Benadryl outcomes

Drug combinations in study:
- Baclofen (baclofen)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Baclofen is effective0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
0.00%
(0 of 3 people)
33.33%
(2 of 6 people)
66.67%
(2 of 3 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/a
Benadryl is effective33.33%
(1 of 3 people)
25.00%
(1 of 4 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
50.00%
(2 of 4 people)
66.67%
(2 of 3 people)
33.33%
(1 of 3 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HeadacheFatigueConstipationDrug DependenceStomach PainBurning EyesPainPain
Suicidal IdeationMicturition Frequency DecreasedHyponatraemiaCoeliac Artery Compression SyndromeMuscle WeaknessHeadache - TensionNausea
NauseaInterruption Of Aortic ArchIleusAcute Respiratory Distress SyndromeJoint PainMenstruation - PainfulFall
FallDrowsinessPostoperative IleusHepatic NecrosisNauseaEye FloatersUrinary Tract Infection
IleusBlood Pressure IncreasedFallConstipationDepression AggravatedEar PainVomiting
HyponatraemiaPressure SorePainPneumoniaAnxiety AggravatedEyes - Sensitive To LightAnxiety
PainDiastolic Blood PressureNervousnessDrug Withdrawal SyndromeDiastolic Blood PressureHeadache
Abdominal PainVision BlurredAbnormal DreamsWithdrawal SyndromeFatigueArthralgia
NervousnessPassed OutUrine Output IncreasedSpinal Compression FractureDrowsinessPain In Extremity
Abnormal DreamsMultiple Sclerosis RelapseExcoriationRoad Traffic AccidentPassed OutDyspnoea

Drug effectiveness by gender :

FemaleMale
Baclofen is effective29.41%
(5 of 17 people)
33.33%
(1 of 3 people)
Benadryl is effective47.06%
(8 of 17 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
NauseaFatigue
FallPain
PainPneumonia
Urinary Tract InfectionNausea
VomitingOsteoarthritis
AnxietyOsteonecrosis Of Jaw
HeadacheInfection
Pain In ExtremityOsteoporosis
DyspnoeaIntervertebral Disc Protrusion
Dry MouthFailure To Thrive

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Baclofen is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 8 people)
22.22%
(4 of 18 people)
6.67%
(1 of 15 people)
n/a50.00%
(1 of 2 people)
Benadryl is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 8 people)
22.22%
(4 of 18 people)
26.67%
(4 of 15 people)
n/a50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aLymphadenopathyMedical Device ComplicationDyspnoeaNauseaHeadacheFallPain
Lymphoproliferative DisorderDysarthriaPyrexiaDyspnoeaSuicidal IdeationPainNausea
Haematocrit DecreasedXanthochromiaVomitingHeadacheNauseaArthralgiaFall
HaematocheziaHeart Rate IncreasedPainHyperthyroidismFatigueUrinary Tract InfectionUrinary Tract Infection
Gastric UlcerDrug Withdrawal SyndromePneumoniaHypothyroidismPain In ExtremityAnxietyVomiting
Aphthous StomatitisDeliriumComa NecPneumoniaOedema PeripheralOsteoarthritisConstipation
PneumoniaSleep DisorderHypotensionDizzinessFallSpinal Column StenosisConfusional State
Rectal HaemorrhageHallucinationCardio-respiratory ArrestVision BlurredPainEmotional DistressAbdominal Pain
Septicaemia StaphylococcalConvulsionUrinary RetentionConstipationAstheniaOsteonecrosis Of JawAsthenia
PyrexiaIleusInfectionPainHysterectomyHypoaesthesiaFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Baclofen and Benadryl on

Do you take Baclofen and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Baclofen and Benadryl
- support group for people who take Baclofen
- support group for people who take Benadryl

Recent conversations of related support groups:

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More questions for: Baclofen, Benadryl

You may be interested at these reviews (Write a review):

  • Diphenhydramine and mental acuity
    For at least 10 years, I have taken diphenhydramine 50 mg. at bedtime for insomnia and allergies. The results have been that I sleep well with no hangover or any cognitive impairment. If I experience vertigo from allergies, I may take an additional 50 mg. but never exceeding 100 mg in a 24 hour period.

    After reading the report regarding an Alzheimer's study finding that after taking as little as 4mg diphenhydramine daily for more than 3 years, dementia rates were high.

    I stopped the diphenhydramine one night. I experienced symptoms of deep brain pulsating pain and severe insomnia. After 4 hours, I took 50 mg diphenhydramine and slept very well. The next night I took 37.5 mg. diphenhydramine, slept very well. However, some of my tasks require layers of mental challenges in which I became slower.

    My question is how did the study recipients obtain 4 mg doses of diphenhydramine when the standard over-the-counter (OTC) availability in tablets is 25 mg? How reliable is the information submitted from the study subjects? What manufacturer's diphendramine was used, or were there several?

    I felt sharper mentally when on 50 mg daily than so far on 37.5 mg.
  • Ampyra vs kidney stones
    Started taking Ampyra Sept 1, 2014.
    Had a severe kidney stone in mid-September.
    Another two weeks ago.
    Another today.
    No family history or them. I also have no history of them.
    Drink fresh squeezed lemon daily and lots of water.
    Take Ibuprofen when it starts up.

    Ampyra is helping with leg strength a tiny bit.
    My MS is 40 years old so it is acting like it is old!
  • Blood sugar level while taking veltrex
    I been taking Veltrex for a viral infection in my eye for 3 days and today my blood sugar was 448.My normal blood sugar runs around 146.
  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless

More reviews for: Baclofen, Benadryl

Comments from related studies:

  • From this study (2 weeks ago):

  • -family history of various autoimmune diseases
    -excessive ear infections if I do not use Vaseline everyday (I have to apply it inside my ear with a q-tip lightly) If I don't do this & scrap the scabs out an ear infection will happen due to all the debris. As soon as I peel the scab off a clear sticky liquid flows out of my ear & creates a new scab
    -endometriosis has ravaged my life & I have had a laproscopy to remove the endometrial tissue off my bladder
    - I am unable to completely empty my bladder without some pain & discomfort
    - I have congenital, cervical kyphosis (my neck is deformed -cervical spinal bones are bent or formed sitting forward) this causes eminence strain on the surrounding muscle & bone. (head & body aches, feelings of fever or "feeling sick/achy" with no viral or infection of any kind)
    -poor eyesight, that became so severe I had no choice but to try lasik with no guarantee that I wouldn't have to wear glasses after.
    -painful sex
    -eyebrows falling out except where they are not suppose to be (stray hairs outside the line of eyebrow)
    -knots on shin bone
    - I have to take excessive amounts of muscle relaxers and Tramadol on a daily bases to be able to do the amount of work normal people do, but I feel aches and pains all day long even with the medications.

    Reply

  • From this study (3 weeks ago):

  • I have chronic fatigue syndrome, fibromyalgia, GERD, IBS, Bipolar 2, PTSD. High levels of anxiety and depression, hypomanic states at times. Hospitalization has been required multiple times to alter drugs. Abuse and overuse of drugs, mixing drugs has been ongoing for 9 weeks. Detox program starting.

    Reply

  • From this study (1 year ago):

  • Past distal injuries returning with increased pressure symptoms. Eye pain with movement. Increased pressure and pain with neck movement. Connective tissue disease - Ehlers Danlos Syndrome.

    Reply

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Complete drug side effects:

On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasms. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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