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Review: Baclofen and Tizanidine

This review analyzes the effectiveness and drug interactions between Baclofen and Tizanidine. It is created by eHealthMe based on 1,643 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 29, 2014: 1,643 people who reported to have interactions when taking Baclofen, Tizanidine Hydrochloride are studied

Trend of Baclofen, Tizanidine Hydrochloride's drug interactions, side effects and effectiveness reports (4084921)

Drug combinations in study:
- Baclofen (baclofen)
- Tizanidine Hydrochloride (tizanidine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Baclofen, Tizanidine Hydrochloride:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Asthenia (weakness)643
Fatigue (feeling of tiredness)424
Fall374
Urinary Tract Infection356
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)336
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)334
Back Pain304
Muscle Spasms (muscle contraction)300
Depression288
Pain282

Most common interactions experienced by people in long term use of Baclofen, Tizanidine Hydrochloride:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Acute Respiratory Distress Syndrome (sudden failure of the respiratory (breathing) system)21
Pneumonia14
Hepatic Necrosis (large portions of liver die off due to severe liver disease)14
Drug Dependence14
Coeliac Artery Compression Syndrome (abdominal pain related to compression of the celiac artery)14
Abdominal Pain12
Biliary Dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)12
Pain12
Abdominal Pain Upper12
Change Of Bowel Habit12

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Baclofen0.00%66.67%33.33%0.00%0.00%
Tizanidine Hydrochloride0.00%0.00%25.00%75.00%0.00%

Top conditions involved for these people * :

  1. Multiple sclerosis
  2. Pain
  3. Muscle spasticity
  4. Muscle spasms
  5. Depression

Top co-used drugs for these people * :

  1. Zanaflex
  2. Tizanidine hcl
  3. Avonex
  4. Neurontin
  5. Tysabri

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Complete drug side effects:

On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasms. Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (3 months ago):

  • I suffer from severe to moderate memory loss a friend told me it was due to klonopin It has been 7 years though since I suffered a concussion in a car accident. Been trying to get disability forever. I can't even handle a minimum wage job bc the steps I have to take r instantly out of my brain. I have a masters degree. So I don't think it's the concussion I think it's the meds. The muscle relaxant r brand new so we can't blame them. So could it be the klonopin

    Reply

  • From this study (5 months ago):

  • Progressive bilat hearing loss r ear worse onset 1-1&1/2 year ms x5 years
    Fell 1/2013 loc concussion tinnitus started sounds like " buzzing heat bugs" non stop could hear over my last mri drives me nuts told may never go away need hearing aids per ent& audiologist do not have $6,000 to buy them saw on internet will these do? Obviously i will research reputable generic brand but is this all ms messing w/ my auditory nerves & can hearing aids really help this is there someone else i should see besides pcp,neurologist,ent md, audiologist
    None of these really know if it will work or not
    Thanks for your time& help

    Reply

  • From this study (13 months ago):

  • Pressure and clogging of ears. Don't notice I'm not hearing out of one ear or the other until hearing comes back out of the blue.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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