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Review: Baclofen and Tizanidine





Summary: drug interactions are reported among people who take Baclofen and Tizanidine together.

This review analyzes the effectiveness and drug interactions between Baclofen and Tizanidine. It is created by eHealthMe based on reports of 1,679 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Baclofen and Tizanidine >>>

What are the drugs

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. (latest outcomes from Baclofen 21,180 users)

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Tizanidine hydrochloride 1,532 users)

On Nov, 29, 2014: 1,679 people who take Baclofen, Tizanidine Hydrochloride are studied

Baclofen, Tizanidine Hydrochloride outcomes

Drug combinations in study:
- Baclofen (baclofen)
- Tizanidine Hydrochloride (tizanidine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Baclofen is effective50.00%
(1 of 2 people)
12.50%
(1 of 8 people)
0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
33.33%
(1 of 3 people)
33.33%
(3 of 9 people)
33.33%
(2 of 6 people)
n/a
Tizanidine Hydrochloride is effective0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
50.00%
(1 of 2 people)
28.57%
(2 of 7 people)
50.00%
(3 of 6 people)
60.00%
(3 of 5 people)
80.00%
(4 of 5 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
SomnolenceDrug DependenceMalaiseCoeliac Artery Compression SyndromeBiliary DyskinesiaMuscle ContractureFatigueFall
Coeliac Artery Compression SyndromeHepatic NecrosisHypotoniaDrug DependenceBiliary Tract DisorderDiaphragm Muscle WeaknessFallFatigue
Acute Respiratory Distress SyndromeConstipationCondition AggravatedHepatic NecrosisPainUrinary Incontinence AggravatedFacial Bones FractureAsthenia
ConstipationCoeliac Artery Compression SyndromeEosinophiliaPneumoniaDiarrhoeaWalking DisabilityHypotensionMultiple Sclerosis
Drug DependencePneumoniaPleural EffusionAcute Respiratory Distress SyndromeAbdominal Pain UpperHallucination, VisualSyncopeUrinary Tract Infection
Hepatic NecrosisAcute Respiratory Distress SyndromeHypotension NosConstipationNauseaSubdural HaematomaMultiple Sclerosis Relapse
PneumoniaGastritisDiabetes MellitusMalaiseDyspepsiaSinus BradycardiaDepression
ArthralgiaHypotension NosHerniaHypotoniaChange Of Bowel HabitDrug HypersensitivityBack Pain
Muscle SpasticityDrug Withdrawal SyndromeMovement DisorderDrug Withdrawal SyndromeAbdominal PainEncephalomalaciaMuscle Spasms
Influenza Like IllnessHallucinations, MixedBradycardia NosBradycardiaAbdominal DistensionBrain ContusionPain

Drug effectiveness by gender :

FemaleMale
Baclofen is effective23.81%
(5 of 21 people)
25.00%
(3 of 12 people)
Tizanidine Hydrochloride is effective45.00%
(9 of 20 people)
45.45%
(5 of 11 people)

Most common drug interactions by gender * :

FemaleMale
FallDepression
FatigueBack Pain
Multiple SclerosisMuscular Weakness
AstheniaHypoaesthesia
Multiple Sclerosis RelapseMuscle Spasms
Urinary Tract InfectionPyrexia
NauseaUrinary Tract Infection
PainDyspnoea
HeadacheArthralgia
Muscle SpasmsAnxiety

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Baclofen is effectiven/an/an/a33.33%
(1 of 3 people)
0.00%
(0 of 8 people)
0.00%
(0 of 16 people)
43.75%
(7 of 16 people)
0.00%
(0 of 5 people)
Tizanidine Hydrochloride is effectiven/an/an/a66.67%
(2 of 3 people)
0.00%
(0 of 7 people)
12.50%
(2 of 16 people)
60.00%
(9 of 15 people)
25.00%
(1 of 4 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Rectal ProlapseFanconi SyndromeGastritisMuscle SpasmsHypoaesthesiaMultiple SclerosisAstheniaUrinary Tract Infection
VomitingDyspnoeaNauseaPain In ExtremityFallMultiple Sclerosis RelapseFall
RetchingConstipationHypotensionArthralgiaBack PainDepressionFatigue
AminoaciduriaAgitationPulmonary EmbolismOedema PeripheralHeadacheFatigueHypotension
DiarrhoeaGrand Mal ConvulsionMalaiseDeep Vein ThrombosisAstheniaUrinary Tract InfectionConvulsion
Renal Tubular DisorderIleusHypotoniaFatigueMultiple Sclerosis RelapseMuscle SpasmsGait Disturbance
PyrexiaHyperpyrexiaPainBack PainMuscle SpasmsDyspnoeaPneumonia
Muscle TightnessClonic ConvulsionDiarrhoeaDry MouthCondition AggravatedFallSomnolence
FatigueCondition AggravatedMyoclonic JerksHeadacheFatiguePainCondition Aggravated
Muscle SpasticityHypothermiaDyspnoeaArthritisDepressionAnxietyBlood Pressure Increased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Baclofen and Tizanidine?

You are not alone! Join a related mobile support group:
- support group for people who take Baclofen and Tizanidine
- support group for people who take Baclofen
- support group for people who take Tizanidine Hydrochloride

Can you answer these questions (Ask a question):

More questions for: Baclofen, Tizanidine Hydrochloride

You may be interested at these reviews (Write a review):

  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Prescribed drugs side effect (1 response)
    I have been on these 2 drugs (Gabapentin and Baclofen) prescribed by my gp for osteoarthritis and nerve damage in my full back.Now also suffering from the grief of losing my beloved companion Harvey (dog),I was diagnosed with deep depression. I was given fluoxetine and have been taking this for almost 4 weeks (along with the other 2 meds) and today I have a very sore tongue and it has been white for a number of days,i am going to the pharmacy tomorrow to seek some advice as I am not sure I should be taking all these together? As I am on the highest dose of depression tablets with the fluoxetine I feel it is unsafe to take with the other 2 as the baclofen can also be used to treat certain types of depression. But I can not do without either and as I am allergic to codeine I am pretty much stuck.
  • Eczema and birth control-microgestin
    I started getting eczema over the last year and recently decided it may be from the birth control as well, which I started taking @ 2 months before I got the eczema and skin started breaking out...weight gain, etc. I am on singulair, westcort cream, moisture/kenalog, exederm cream, cerevue wash, cetaphil moisturizer, and started using the black soap which is apparently helping. I started a vegetarian diet and eat mainly the same foods daily to monitor anything for allergies. I stopped taking the pill 3 days ago and I am optimistic. I am hoping others have had positive experiences.
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.
  • Chills while on tizanidine
    Extremely sensitive to cold and have chills several times a day

More reviews for: Baclofen, Tizanidine Hydrochloride

Comments from related studies:

  • From this study (7 months ago):

  • Around every three months I have a severe attack of rigors.

    Reply

  • From this study (9 months ago):

  • would like to restart tysabri and amprya to increase muscle/nerve activity in legs and to walk.

    Reply

  • From this study (12 months ago):

  • I suffer from severe to moderate memory loss a friend told me it was due to klonopin It has been 7 years though since I suffered a concussion in a car accident. Been trying to get disability forever. I can't even handle a minimum wage job bc the steps I have to take r instantly out of my brain. I have a masters degree. So I don't think it's the concussion I think it's the meds. The muscle relaxant r brand new so we can't blame them. So could it be the klonopin

    Reply

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Complete drug side effects:

On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasms. Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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