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Review: taking Baclofen and Tramadol together

Summary: drug interactions are reported among people who take Baclofen and Tramadol together.

This review analyzes the effectiveness and drug interactions between Baclofen and Tramadol. It is created by eHealthMe based on reports of 956 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 12, 2015: 956 people who take Baclofen, Tramadol are studied

Baclofen, Tramadol outcomes

Drug combinations in study:
- Baclofen (baclofen)
- Tramadol (tramadol hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Baclofen is effective12.50%
(1 of 8 people)
(2 of 15 people)
(2 of 6 people)
(2 of 9 people)
(4 of 8 people)
(2 of 7 people)
(2 of 5 people)
Tramadol is effective50.00%
(1 of 2 people)
(1 of 9 people)
(3 of 12 people)
(6 of 13 people)
(5 of 14 people)
(2 of 9 people)
(1 of 2 people)

Drug effectiveness by gender :

Baclofen is effective30.23%
(13 of 43 people)
(2 of 15 people)
Tramadol is effective35.56%
(16 of 45 people)
(3 of 15 people)

Drug effectiveness by age :

Baclofen is effectiven/an/a100.00%
(1 of 1 people)
(1 of 10 people)
(3 of 32 people)
(4 of 22 people)
(2 of 21 people)
(4 of 18 people)
Tramadol is effectiven/an/a100.00%
(1 of 1 people)
(0 of 11 people)
(4 of 31 people)
(4 of 25 people)
(4 of 21 people)
(6 of 19 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Confusional StateAbnormal Weight GainBone PainChest PainIntentional OverdoseInsomniaMenstruation - PainfulNausea
ThrombocytopeniaFailed Back Surgery SyndromeAbnormal Weight GainEar DiscomfortDrug IneffectiveCholelithiasisPainHeadache
Renal Failure AcuteIncreased Tendency To BruiseSinusitisEar DisorderDepressionAbdominal PainHeadache - TensionFall
FallFallTremorDry MouthSuicidal IdeationFastingEye FloatersPain
Serotonin SyndromeLactic AcidosisMenstrual Cycle ProlongedLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessSuicide AttemptConvulsionEar PainVomiting
ConvulsionRenal FailureMigraine AggravatedHearing LossRespiratory DistressCholecystitisFastingFatigue
Pneumonia AspirationParanoiaPitting OedemaFailed Back Surgery SyndromeOverdoseRespiratory FailureEyes - Sensitive To LightDizziness
Overdose NosConfusional StateAppetite IncreasedEar PainComaSomnolenceHair LossMuscle Spasms
Musculoskeletal PainHair LossLivedo ReticularisEar PruritusAlcoholismDisorientationHypoaesthesia
VomitingHeart RacingDecreased ActivitySyncopeAlcohol PoisoningHigh Blood PressureArthralgia

Most common drug interactions by gender * :

DizzinessMuscle Spasms
AstheniaDrug Withdrawal Syndrome
Muscle SpasmsDepression

Most common drug interactions by age * :

n/an/aHyperaesthesiaPainHypoaesthesiaHeadacheUrinary Tract InfectionFall
Withdrawal HypertensionVomitingVomitingNauseaNauseaPain
Carotid Artery OcclusionNauseaFatigueLoss Of ConsciousnessAsthenia
LethargyFallDizzinessWeight DecreasedNausea
NauseaChest PainPyrexiaHeadacheHypertension
HemiparesisAbdominal PainMuscle SpasmsPneumoniaInsomnia
Blood Albumin DecreasedHeadacheFallHypoaesthesiaConfusional State
Respiratory Rate IncreasedDrug Withdrawal SyndromeInsomniaDehydrationChest Pain
Upper Airway ObstructionDyspepsiaDepressionFatigueDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Baclofen
- support group for people who take Tramadol

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasms. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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