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Review: taking Bactrim Ds and Allopurinol together

Summary: drug interactions are reported among people who take Bactrim Ds and Allopurinol together.

This review analyzes the effectiveness and drug interactions between Bactrim Ds and Allopurinol. It is created by eHealthMe based on reports of 2,479 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. (latest outcomes from 6,920 Bactrim ds users)

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from 51,464 Allopurinol users)

On Feb, 27, 2015: 2,478 people who take Bactrim Ds, Allopurinol are studied

Bactrim Ds, Allopurinol outcomes

Drug combinations in study:
- Bactrim Ds (sulfamethoxazole; trimethoprim)
- Allopurinol (allopurinol)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Bactrim Ds is effective0.00%
(0 of 1 people)
(0 of 1 people)
(1 of 1 people)
Allopurinol is effectiven/a50.00%
(1 of 2 people)
(1 of 1 people)
(2 of 2 people)

Drug effectiveness by gender :

Bactrim Ds is effective0.00%
(0 of 1 people)
(1 of 2 people)
Allopurinol is effective0.00%
(0 of 1 people)
(4 of 4 people)

Drug effectiveness by age :

Bactrim Ds is effectiven/an/an/an/an/an/a0.00%
(0 of 1 people)
(1 of 2 people)
Allopurinol is effectiven/an/an/an/an/an/a50.00%
(1 of 2 people)
(3 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaBlood Creatinine IncreasedHyperuricaemiaMultiple MyelomaDiarrhoeaDiarrhoeaPyrexia
Renal Failure AcuteWhite Blood Cell Count DecreasedPyrexiaPlatelet Count DecreasedAtrial FibrillationLeukopeniaPlatelet Count Decreased
HypotensionFebrile NeutropeniaDiarrhoeaAnaemiaMalaiseOliguriaAnaemia
SepsisRenal Failure AcuteUrinary Tract InfectionBlood Alkaline Phosphatase IncreasedDecreased AppetiteRenal Failure AcuteFebrile Neutropenia
Febrile NeutropeniaAnaemiaTransplant FailureDisseminated Intravascular CoagulationHepatic SteatosisBlood Creatine Phosphokinase IncreasedThrombocytopenia
Renal FailurePlatelet Count DecreasedWhite Blood Cell Count DecreasedNeutrophil Count DecreasedLymphomaBlood Bilirubin IncreasedWhite Blood Cell Count Decreased
White Blood Cell Count DecreasedDehydrationHeart Valve IncompetenceHaemorrhageHyperlipidaemiaAlanine Aminotransferase IncreasedPneumonia
Multi-organ FailureHyperglycaemiaPneumoniaCerebral HaemorrhageOedema PeripheralAspartate Aminotransferase IncreasedDyspnoea
PancytopeniaPneumoniaPlatelet Count DecreasedCholecystitis AcuteGamma-glutamyltransferase IncreasedFatigue
Disseminated Intravascular CoagulationHypotensionAnaemiaOsteopeniaAlanine Aminotransferase IncreasedNausea

Most common drug interactions by gender * :

Febrile NeutropeniaPlatelet Count Decreased
Platelet Count DecreasedDyspnoea
Renal Failure AcuteWhite Blood Cell Count Decreased
ThrombocytopeniaFebrile Neutropenia
HypotensionRenal Failure Acute

Most common drug interactions by age * :

Toxic Epidermal NecrolysisHaemolytic Uraemic SyndromeHypotensionPlatelet Count DecreasedPyrexiaDyspnoeaPyrexiaPlatelet Count Decreased
ConvulsionToxic Epidermal NecrolysisPain In ExtremityPyrexiaHyperglycaemiaPainAnaemiaPyrexia
ChloromaFebrile NeutropeniaBlood Bilirubin IncreasedWhite Blood Cell Count DecreasedPlatelet Count DecreasedAnxietyRenal Failure AcuteFebrile Neutropenia
HypertoniaPyrexiaRenal FailureDiarrhoeaHaemoglobin DecreasedNauseaWhite Blood Cell Count DecreasedAnaemia
HydrocephalusCoughPneumonitisDyspnoeaDehydrationNeuropathy PeripheralFatigueThrombocytopenia
PyrexiaPulmonary Veno-occlusive DiseaseAcute Respiratory Distress SyndromeAbdominal PainAnaemiaPneumoniaPlatelet Count DecreasedWhite Blood Cell Count Decreased
Respiratory ArrestMuscle RigidityNephrogenic Systemic FibrosisCatheter Related InfectionDizzinessFatiguePainHaemoglobin Decreased
Acute Myeloid LeukaemiaNeutropeniaPyrexiaPancytopeniaNeutrophil Count DecreasedInjuryPancytopeniaDiarrhoea
Feeling JitteryDisorientationCardiac ArrestPainFatigueRenal FailureFebrile NeutropeniaPneumonia
Agitation NeonatalEnterococcal InfectionPlatelet Count DecreasedHypokalaemiaAbdominal Pain UpperNeutropeniaDiarrhoeaNausea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Bactrim Ds and Allopurinol?

You are not alone! Join a related mobile support group:
- support group for people who take Bactrim Ds and Allopurinol
- support group for people who take Allopurinol
- support group for people who take Bactrim Ds

Can you answer these questions (Ask a question):

  • Can i use a lidocaine patch for back pain if i am taking prograf for anti-rejection post lung transplant?
    Transplant was 6 years ago.
    Has suffered from PTLD on several occasions before.
    Recently hospitalized for Periodic Fever Syndrome.
    Received Interleukin 6 blocker last week and fevers have resolved, but back pain is still present
  • Can bactrim ds treat shingle?
    I am wondering can Bactrim DS treat shingles? Because l am HIV POSITIVE my specialist prescribed me Bactrim DS and Atripla, and l realise Bactrim DS is an antiviral tablets that is why l like to know whether l can use Bactrim DS to treat shingles. This is the second times l have shingles. Please help me!
  • Can i take a steroid while taking xarelto (1 answer)
    I took prednisone for constant cough. had 3rd surgery on back one year ago. Had to patch spinal cord. Got blood clots. Had pulmonary embolism. Now have severe bronchitis. I know the prednisone will take care of cough, but what else?
  • I have classic hemochromatosis and p-vera disease what should i expect
    I wonder what my prognosis is for the future I am 62 years old and have lost muscle mass. I also have a very enlarged spleen. I have p-vera disorder and classic hemochromatosis
  • Can i take reglan and allopurinol together
    I need to know if i can take reglan and allopurinol together. I have nasea and uric acid problems and i am tierd of feeling like vomiting and i dont know what to take for nasea and wont interract with allopurinol thank you.

More questions for: Allopurinol, Bactrim Ds

You may be interested at these reviews (Write a review):

  • Bactrim-hypopigmentation, nausea, other side effects
    Took bactrim for 7 days 2x a day, was told to take for 14 days. Had persistent and worsening nausea, vomiting, fatigue, hypopigmentation of my skin when I sat in the sun for over 5 minutes, inability to fall asleep, headache, and neck pain. Ended up with low iron and folic acid levels, which were treated with supplements and discontinuation of the Bactrim resolved symptoms.
  • Uti symptoms for woman
    I had the tingling and dumbness in my feet for weeks until I went to doctor, I had ATI after antibiotic nothing.

  • Allop├╝rinol and achilles tendinitis
    I take allopurinol on a purely prophylactic basis, as my father has got gout and kidney stones. Since three months I suffer from achilles tendinitis; I put it down to overload; I am rather heavy and play a lot of tennis, besides moving a lot at work. As always, I tried to "walk through" my weight associated problems, but it did not get any better. Non-compliant, I stopped taking allopurinol for the last three days, and, surprise surprise, the pain is quickly abating, in spite of playing prolonged matches the last three days. I remembered that gyrase inhibitors (e.g. ciprofloxacin) predispose to achilles tendon rupture, a fact that I was personal witness with a female player at our club. So I speculate on a causal link between allopurinol and achilles tendinitis
  • Bactrim causes severe side effects (1 response)
    I get bladder infections on a regular basis. I do not have a doctor so I end up in the ER every time. I normally go to the same ER but not all the time. I have been prescribed medications like Cipro and Bactrim. Cipro usually knocks out the infection but I always get another one.
    For the last three years Doctors have been prescribing me Bactrim. In the last two months I had three bladder infections and took Bactrim for ten days seven and three. I didn't realize the medications themselves would harm me as well. Now I have severe abdominal pain every single day. I did some research on Bactrim and discovered it can cause several different kinds of stomach problems. I have been in pain for two months straight non-stop.
    I finally discovered that the Bactrim killed both the good and bad bacteria in my body and now my digestive system is off balance. I went to a natural food store and bought some probiotics. It helped relieve some stomach pain after four days, but if I forget to take it one time it comes back. I think something is wrong with me but not exactly sure what. When I get a doctor next month I will update this article.
    I just want to say that Bactrim has severe side effects, I DO NOT recommend taking this drug. Cipro is better in the long run.
  • Allopurinol for 6-mp metabolism to 6-tgn
    I began taking Allopurinol 100mg to help metabolize the Purinethol I have been taking for 6 years for Crohn's disease after a blood test revealed my 6-MMP metabolites were too high and 6-TG were too low. Several published studies show Allopurinol to be helpful for "non-preferential metabolizers" like me, to help shunt the metabolic pathway towards therapeutic 6-TG.

    After 1 week of Allopurinol, I had to discontinue the drug due to debilitating nausea, which was worst in the morning.

More reviews for: Allopurinol, Bactrim Ds

Comments from related studies:

  • From this study (2 years ago):

  • kidney transplant April 16th 2002


  • From this study (2 years ago):

  • I began Rapamune 11-8-12. I stopped rapamune 12-13-12 I have had liquid diarrhea 20 to 30x a day and am incontient at times. I began liquid diarrhea 11-6-12 or sooner and continue to have


  • From this study (2 years ago):

  • I began Rapamune 11-8-12. I have had liquid diarrhea 20 to 30x a day and am incontient at times.


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Complete drug side effects:

On eHealthMe, Bactrim Ds (sulfamethoxazole; trimethoprim) is often used to treat urinary tract infection. Allopurinol (allopurinol) is often used to treat gout. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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