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Review: Bactrim Ds and Allopurinol

This review analyzes the effectiveness and drug interactions between Bactrim Ds and Allopurinol. It is created by eHealthMe based on 2,468 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 4, 2014: 2,468 people who reported to have interactions when taking Bactrim Ds, Allopurinol are studied

Trend of Bactrim Ds, Allopurinol's drug interactions, side effects and effectiveness reports (4077089)

Drug combinations in study:
- Bactrim Ds (sulfamethoxazole; trimethoprim)
- Allopurinol (allopurinol)

eHealthMe real world results:

Most common interactions experienced by people in the use of Bactrim Ds, Allopurinol:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pyrexia (fever)1,144
Platelet Count Decreased945
Dyspnoea (difficult or laboured respiration)683
Anaemia (lack of blood)547
Febrile Neutropenia (fever with reduced white blood cells)526
White Blood Cell Count Decreased464
Thrombocytopenia (decrease of platelets in blood)461
Renal Failure Acute (rapid kidney dysfunction)432

Most common interactions experienced by people in long term use of Bactrim Ds, Allopurinol:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Platelet Count Decreased24
Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)21
Hyperuricaemia (level of uric acid in the blood that is abnormally high)20
Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)18
Hyperlipidaemia (presence of excess lipids in the blood)16
Malaise (a feeling of general discomfort or uneasiness)14
Multiple Myeloma (cancer of the plasma cells)14
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell)14
Blood Alkaline Phosphatase Increased12
Disseminated Intravascular Coagulation (systemic activation of blood coagulation)12

How effective are the drugs:


Top conditions involved for these people * :

  1. Prophylaxis
  2. Diffuse large b-cell lymphoma
  3. Multiple myeloma
  4. Chronic lymphocytic leukaemia
  5. Acute lymphocytic leukaemia

Top co-used drugs for these people * :

  1. Cyclophosphamide
  2. Acyclovir
  3. Cotrim
  4. Vincristine
  5. Sulfamethoxazole and trimethoprim

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Allopurinol, Bactrim Ds

You can also:

Complete drug side effects:

On eHealthMe, Bactrim Ds (sulfamethoxazole; trimethoprim) is often used to treat urinary tract infection. Allopurinol (allopurinol) is often used to treat gout. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 year ago):

  • kidney transplant April 16th 2002


  • From this study (1 year ago):

  • I began Rapamune 11-8-12. I stopped rapamune 12-13-12 I have had liquid diarrhea 20 to 30x a day and am incontient at times. I began liquid diarrhea 11-6-12 or sooner and continue to have


  • From this study (1 year ago):

  • I began Rapamune 11-8-12. I have had liquid diarrhea 20 to 30x a day and am incontient at times.


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More questions for: Allopurinol, Bactrim Ds

You may be interested at these reviews (what is this?):

  • Interaction between bactrim & vit c
    I drank one tablet of bactrim with glass of vit C (1 tablet), after 5 minutes I became red (face & eyes) with high tachycardia and high pressure in the ears. After 15 minutes I observed differents red points on the skin (hand, arms & legs). I would like to inform you that I took in the past bact ...

  • Allopurinol and muscle cramps
    Approximately 5 years ago I developed gout and my physician prescribed allopurinol. After a period of time I began to have muscle spasms in the calves of my legs at night. My doctor gave me a prescription for restless leg syndrome, which helped for a short time. I was then given a different presc ...

More reviews for: Allopurinol, Bactrim Ds

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Allopurinol side effects
- Bactrim Ds side effects



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