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Review: taking Bupropion and Mucinex together

Summary: drug interactions are reported among people who take Bupropion and Mucinex together.

This review analyzes the effectiveness and drug interactions between Bupropion and Mucinex. It is created by eHealthMe based on reports of 356 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 29, 2015: 356 people who take Bupropion Hydrochloride, Mucinex are studied

Bupropion Hydrochloride, Mucinex outcomes

Drug combinations in study:
- Bupropion Hydrochloride (bupropion hydrochloride)
- Mucinex (guaifenesin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Bupropion Hydrochloride is effective100.00%
(1 of 1 people)
(1 of 2 people)
(2 of 2 people)
(0 of 2 people)
(3 of 7 people)
(0 of 1 people)
(3 of 5 people)
Mucinex is effective30.00%
(3 of 10 people)
(0 of 1 people)
(2 of 2 people)
(4 of 4 people)
(0 of 1 people)

Drug effectiveness by gender :

Bupropion Hydrochloride is effective33.33%
(4 of 12 people)
(6 of 8 people)
Mucinex is effective60.00%
(6 of 10 people)
(3 of 8 people)

Drug effectiveness by age :

Bupropion Hydrochloride is effectiven/an/a50.00%
(1 of 2 people)
(2 of 3 people)
(0 of 10 people)
(3 of 5 people)
(2 of 5 people)
(2 of 5 people)
Mucinex is effectiven/an/a0.00%
(0 of 1 people)
(2 of 3 people)
(1 of 10 people)
(1 of 5 people)
(2 of 3 people)
(3 of 6 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainCoughFatiguePulmonary EmbolismCoughAnxietyProductive CoughPain
ConvulsionDiverticulumRosaceaDyspnoeaPneumoniaLoss Of ConsciousnessEdema - Peripheral, Peripheral EdemaDepression
DizzinessOsteonecrosis Of JawRenal Failure ChronicDepressionSpinal Column StenosisStaringFatigue - ChronicNausea
Obsessive-compulsive DisorderMassMusculoskeletal DisorderDeep Vein ThrombosisMassUrinary Tract InfectionPeyronie's DiseaseCough
Self-injurious IdeationOsteomyelitisMalaiseHeart InjuryAnxietyStatus EpilepticusCoughAnxiety
Panic ReactionSquamous Cell Carcinoma Of SkinTesticular FailureChest PainOsteomyelitisUrinary IncontinenceDepressed MoodDyspnoea
Disturbance In AttentionDental CariesEdema - Peripheral, Peripheral EdemaRight Ventricular FailureDiverticulumDizzinessFall
Feeling Of DespairSpinal Column StenosisProductive CoughPalpitationsSquamous Cell Carcinoma Of SkinLethargyBack Pain
Serotonin SyndromePneumoniaFatigue - ChronicAnxietyDental CariesEscherichia InfectionHeadache
SomnolenceInflammationHypertensive NephropathyPain In ExtremityInflammationElectroencephalogram AbnormalInjury

Most common drug interactions by gender * :

InjuryRespiratory Distress
Back PainHeadache
Chest PainWeight Decreased

Most common drug interactions by age * :

n/an/aPainPainDeep Vein ThrombosisHeadacheAnxietyCough
Homicidal IdeationPulmonary EmbolismSinusitisBack PainPainNausea
Hallucination, AuditoryDeep Vein ThrombosisAnxietySinusitisCoughVomiting
Psychotic DisorderEmotional DistressPneumoniaDyspnoeaDepressionPneumonia
DroolingChest PainChest DiscomfortDepressionNauseaAbdominal Pain
Sinus TachycardiaPain In ExtremityPanic AttackPainInsomniaWeight Decreased
DysarthriaAnhedoniaInjuryAnxietyOedema PeripheralDepression
Pupillary Reflex ImpairedInjuryDyspnoeaPneumoniaEmphysemaDyspnoea
ConvulsionDyspnoeaPainFallSpinal OsteoarthritisFatigue
Suicide AttemptCholelithiasisDepressionDiabetes MellitusHeadacheHypertension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Bupropion Hydrochloride
- support group for people who take Mucinex

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Bupropion Hydrochloride (bupropion hydrochloride) is often used to treat depression. Mucinex (guaifenesin) is often used to treat cough. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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