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Review: Buspar and Cyclobenzaprine

This review analyzes the effectiveness and drug interactions between Buspar and Cyclobenzaprine. It is created by eHealthMe based on reports of 473 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Buspar and Cyclobenzaprine >>>

What are the drugs

Buspar (latest outcomes from 11,026 users) has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety.

Cyclobenzaprine hydrochloride (latest outcomes from 2,360 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

On Sep, 14, 2014: 473 people who take Buspar, Cyclobenzaprine Hydrochloride are studied

Buspar, Cyclobenzaprine Hydrochloride outcomes

Drug combinations in study:
- Buspar (buspirone hydrochloride)
- Cyclobenzaprine Hydrochloride (cyclobenzaprine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Buspar is effective0.00%
(0 of 1 people)
(0 of 8 people)
(0 of 7 people)
(1 of 2 people)
(3 of 6 people)
(0 of 1 people)
(3 of 4 people)
Cyclobenzaprine Hydrochloride is effective0.00%
(0 of 4 people)
(2 of 6 people)
(1 of 3 people)
(0 of 4 people)
(1 of 5 people)
(4 of 5 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Abnormal DreamsDyspnoeaPulseTinnitusPainPainHypothyroidismPain
Panic AttackPulmonary FibrosisPanic AttackSneezingGallbladder DisorderAnxietyAnxiety And StressDepression
Livedo ReticularisPresyncopeHigh Blood CholesterolRestless Leg SyndromePancreatitisEmotional DistressBipolar 1Anxiety
Hepatic FailureGeneral Physical Health DeteriorationViolence-related SymptomHigh Blood PressureCholecystitis ChronicPeripheral IschaemiaHypertensionChest Pain
Heart Rate IncreasedChest DiscomfortAnxiety DisorderHigh Blood CholesterolSphincter Of Oddi DysfunctionCyanosisMuscle ContractureNausea
Multi-organ FailureInjuryChronic DepressionMuscle PainDizzinessSphincter Of Oddi DysfunctionMigraineBack Pain
Haemoglobin DecreasedPalpitationsHigh Blood PressureSleep Disorder Due To General Medical Condition, Insomnia TypeNervousnessCholecystitis ChronicHeart Disease - AgingWeight Increased
Rectal HaemorrhageChest PainRestless Leg SyndromeDry MouthLightheadedness - FaintingPancreatitisDrug Ineffective
PulsePainAcid RefluxDry SkinShortness Of BreathGallbladder DisorderType 2 Diabetes Mellitus
Suicide AttemptAnxietyDizzinessSwelling Of The Ankles - Feet - LegsSwelling Of The Ankles - Feet - LegsDrug HypersensitivityDyspnoea

Drug effectiveness by gender :

Buspar is effective26.92%
(7 of 26 people)
(0 of 3 people)
Cyclobenzaprine Hydrochloride is effective28.00%
(7 of 25 people)
(1 of 3 people)

Most common drug interactions by gender * :

AnxietySuicidal Ideation
Chest PainAnxiety
Back PainBipolar I Disorder
Drug IneffectiveEmotional Distress
Type 2 Diabetes MellitusHypotension
Weight IncreasedMemory Impairment

Drug effectiveness by age :

Buspar is effectiven/an/an/a14.29%
(1 of 7 people)
(1 of 13 people)
(5 of 30 people)
(0 of 12 people)
(0 of 7 people)
Cyclobenzaprine Hydrochloride is effectiven/an/an/a20.00%
(1 of 5 people)
(3 of 14 people)
(3 of 30 people)
(1 of 12 people)
(0 of 7 people)

Most common drug interactions by age * :

n/an/aPainPulmonary EmbolismLoss Of ConsciousnessAnxietyType 2 Diabetes MellitusDepression
Gallbladder DisorderMuscle SpasmsCompleted SuicidePainWeight IncreasedDyspnoea
PancreatitisCholelithiasisRespiratory DepressionDepressionDiabetic NeuropathyUrinary Tract Infection
Cholecystitis ChronicAnxietySerotonin SyndromeType 2 Diabetes MellitusAnxietyAgitation
Sphincter Of Oddi DysfunctionDyspepsiaOverdoseWeight IncreasedDiabetes MellitusFall
Pulmonary EmbolismPainNeck PainRashOedema PeripheralChest Discomfort
Deep Vein ThrombosisTooth FractureAnticholinergic SyndromeHeadacheDiabetic GastroparesisAnxiety
VomitingNauseaDrug IneffectiveDiabetic RetinopathyAsthenia
TachycardiaWeight IncreasedEmotional DistressDiabetes Mellitus Inadequate ControlNeck Pain
Gallbladder DisorderStaphylococcal InfectionSuicidal IdeationPainChest Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Buspar and Cyclobenzaprine?

Get connected! Join a mobile support group:
- group for people who take Buspar and Cyclobenzaprine
- group for people who take Buspar
- group for people who take Cyclobenzaprine Hydrochloride

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  • Don't handle busy, large crowds well at all. Unfamiliar social settings rapidly increase my anxiety level. When arguing with my spouse, or anyone else, I become highly anxious, sometimes to the point of outward fits of rage. When I feel myself going into a fit of rage, many times I cannot control myself. In my rage fits I always completely disregard my own safety regardless of the implied harm to myself others in my vicinity.


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Complete drug side effects:

On eHealthMe, Buspar (buspirone hydrochloride) is often used to treat stress and anxiety. Cyclobenzaprine Hydrochloride (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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