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Review: taking Buspar and Xanax together

Summary: drug interactions are reported among people who take Buspar and Xanax together.

This review analyzes the effectiveness and drug interactions between Buspar and Xanax. It is created by eHealthMe based on reports of 1,390 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 14, 2015: 1,390 people who take Buspar, Xanax are studied

Buspar, Xanax outcomes

Drug combinations in study:
- Buspar (buspirone hydrochloride)
- Xanax (alprazolam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Buspar is effective12.50%
(2 of 16 people)
(3 of 18 people)
(3 of 10 people)
(4 of 12 people)
(3 of 7 people)
(4 of 7 people)
(2 of 3 people)
Xanax is effective40.00%
(4 of 10 people)
(5 of 12 people)
(6 of 10 people)
(9 of 19 people)
(9 of 12 people)
(13 of 14 people)
(4 of 5 people)

Drug effectiveness by gender :

Buspar is effective32.20%
(19 of 59 people)
(2 of 14 people)
Xanax is effective62.69%
(42 of 67 people)
(8 of 15 people)

Drug effectiveness by age :

Buspar is effectiven/a0.00%
(0 of 1 people)
(2 of 17 people)
(9 of 88 people)
(6 of 34 people)
(3 of 28 people)
(1 of 8 people)
Xanax is effectiven/a100.00%
(1 of 1 people)
(1 of 2 people)
(8 of 18 people)
(19 of 92 people)
(9 of 34 people)
(10 of 30 people)
(2 of 9 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Suicide AttemptDizzinessNeuropathy PeripheralType 2 Diabetes MellitusPancreatitisAnxietyNail DisorderAnxiety
Intentional OverdoseBurning SensationMusculoskeletal DisorderDiabetes Mellitus Inadequate ControlCholecystitis ChronicWeight IncreasedMyofascial Pain SyndromeDepression
AggressionPalpitationsDiabetic NeuropathyDiabetic NephropathySphincter Of Oddi DysfunctionDizzinessNasal CongestionNausea
PainTremorBlood Triglycerides IncreasedDecubitus UlcerPainInsomniaNervous System DisorderPain
DysphagiaAnxietySpinal Column StenosisNeuropathy PeripheralGallbladder DisorderFearPanic AttackChest Pain
Bipolar I DisorderFeeling AbnormalType 2 Diabetes MellitusDizzinessDizzinessMajor DepressionMyocardial InfarctionFatigue
ScarNervousnessBlood Cholesterol IncreasedAcid RefluxFatigueSuicidal IdeationMuscular WeaknessDyspnoea
Memory ImpairmentPanic AttackBack PainGrand Mal ConvulsionAnxietyPollakiuriaFlatulenceDizziness
Burns Third DegreeConstipationHyperlipidaemiaCryingDiarrhoeaHyperglycaemiaGlossodyniaFall
DepressionDepressionFatigueFatigueFallFood CravingHypoaesthesiaInsomnia

Most common drug interactions by gender * :

Chest PainFatigue
PainSuicidal Ideation
Oedema PeripheralChest Pain
FatigueDrug Ineffective

Most common drug interactions by age * :

Diabetes Mellitusn/aPainAnxietyCompleted SuicideAnxietyFatigueDizziness
HyperglycaemiaDepressionDepressionDiabetes MellitusDepressionFallNausea
Food CravingGallbladder DisorderDyspnoeaType 2 Diabetes MellitusInsomniaDepressionConfusional State
FearSphincter Of Oddi DysfunctionPanic AttackSuicide AttemptChest PainAnxietyDyspnoea
AnxietyCholecystitis ChronicHeadacheDrug Toxicity NosType 2 Diabetes MellitusCompleted SuicideCardiac Failure Congestive
Major DepressionSubstance AbuseChest PainDyspepsiaSuicidal IdeationDrug IneffectiveFatigue
Weight IncreasedConfusional StateBlood Cholesterol IncreasedChest PainHeadacheDizzinessAnxiety
Suicidal IdeationMental ImpairmentDizzinessDrug Withdrawal SyndromeOedema PeripheralInsomniaSyncope
PollakiuriaDehydrationFatigueDiabetes Mellitus Inadequate ControlNauseaChest PainPain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Buspar and Xanax?




You are not alone! Join a related support group:
- support group for people who take Buspar
- support group for people who take Xanax

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Buspar (buspirone hydrochloride) is often used to treat stress and anxiety. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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