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Review: Cardizem and Xarelto

This review analyzes the effectiveness and drug interactions between Cardizem and Xarelto. It is created by eHealthMe based on reports of 96 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Cardizem and Xarelto >>>

What are the drugs

Cardizem (what 16,408 Cardizem users reported?) has active ingredients of diltiazem hydrochloride. It is used in high blood pressure.

Xarelto (what 4,666 Xarelto users reported?) has active ingredients of rivaroxaban. It is used in atrial fibrillation/flutter.

On Aug, 11, 2014: 96 people who take Cardizem, Xarelto are studied

Cardizem, Xarelto outcomes

Drug combinations in study:
- Cardizem (diltiazem hydrochloride)
- Xarelto (rivaroxaban)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cardizem is effective33.33%
(1 of 3 people)
(1 of 3 people)
(0 of 1 people)
(1 of 3 people)
Xarelto is effective100.00%
(2 of 2 people)
(1 of 2 people)
(1 of 2 people)
(0 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Hepatic Enzyme IncreasedHepatic Enzyme IncreasedHepatic Enzyme IncreasedCoughMultiple Allergiesn/an/aDyspnoea
Gastritis ErosiveGastritis ErosiveGastritis ErosiveLipidsHypertensionGastrointestinal Haemorrhage
Skeletal InjuryGastrointestinal HaemorrhageColon CancerCarditisAstheniaHepatic Enzyme Increased
Balance DisorderJaundice CholestaticMelaenaAsthmaEpistaxis
DehydrationDyspnoeaHepatotoxicityAtrial Fibrillation/flutterAnaemia
HallucinationPericardial HaemorrhageAlanine Aminotransferase IncreasedFeeling HotHaemoptysis
HypoglycaemiaChest PainErectile DysfunctionStomach PainGastritis Erosive
HyperkalaemiaCardiac TamponadeHepatocellular InjuryEustachian Tube DysfunctionHyperkalaemia
Decreased AppetiteAbdominal PainHypoglycaemia
Head InjuryHypotensionHaematuria

Drug effectiveness by gender :

Cardizem is effective33.33%
(2 of 6 people)
(1 of 4 people)
Xarelto is effective80.00%
(4 of 5 people)
(1 of 3 people)

Most common drug interactions by gender * :

Gastrointestinal HaemorrhageHepatic Enzyme Increased
Chest PainHaemoptysis
DizzinessGastritis Erosive
DehydrationGastrointestinal Haemorrhage
Balance DisorderEpistaxis
Skeletal InjuryHyperkalaemia
Decreased AppetiteRenal Failure

Drug effectiveness by age :

Cardizem is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
(3 of 24 people)
Xarelto is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
(5 of 22 people)

Most common drug interactions by age * :

n/an/an/an/an/aGastrointestinal HaemorrhageGastritis ErosiveDyspnoea
ArrhythmiaHepatic Enzyme IncreasedGastrointestinal Haemorrhage
Gastric UlcerChest PainEpistaxis
FatigueCardiac TamponadeAnaemia
Erectile DysfunctionDyspnoeaDizziness
Abdominal PainBalance Disorder
Pericardial HaemorrhageDehydration
Gastrointestinal HaemorrhageSkeletal Injury
Jaundice CholestaticHaematuria

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Cardizem and Xarelto
- group for people who take Cardizem
- group for people who take Xarelto

Comments from related studies:

  • From this study (4 days ago):

  • seems to happen about 6 hours after taking rivaroxaban , always overnight, decreses in the daytime after getting up.


  • From this study (2 months ago):

  • I have had rat bite fever, 1957; pylo9inidal cyst; PVC's, Hypoglycemia,p Hyperglycemia; Esophagitis; Diverticulitis; Ulcerative colitis; heart attack; gall bladder removal; adrenal adenoma; osteoma of the ear canal; kidney stones; prostatitis; agent orange exposure


  • From this study (7 months ago):

  • Just a slight cough, non-productive, involuntary


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Complete drug side effects:

On eHealthMe, Cardizem (diltiazem hydrochloride) is often used to treat high blood pressure. Xarelto (rivaroxaban) is often used to treat atrial fibrillation/flutter. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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