Drug interactions between Celexa and Lamictal Xr
This is a real world study of Celexa and Lamictal Xr drug interactions. The study is created by eHealthMe based on 1,289 reports from FDA.
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What are the drugs
Celexa has active ingredients of citalopram hydrobromide. It is used in depression, stress and anxiety, generalized anxiety disorder, dysthymia, depressed mood, major depression.
Lamictal xr has active ingredients of lamotrigine. It is used in epilepsy, bipolar disorder, seizures, mood swings, dysthymia.
On Apr, 26, 2013: 1,289 people who reported to have interactions when taking Lamictal Xr, Celexa are studied

Drug combinations in study:
- Lamictal Xr (lamotrigine)
- Celexa (citalopram hydrobromide)
Most common interactions experienced by people in the use of Lamictal Xr, Celexa:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Rash | 231 |
| 2 | Somnolence | 209 |
| 3 | Vomiting | 191 |
| 4 | Pyrexia | 154 |
| 5 | Dizziness | 102 |
| 6 | Drug Interaction | 82 |
| 7 | Tremor | 80 |
| 8 | Headache | 74 |
| 9 | Nausea | 74 |
| 10 | Convulsion | 74 |
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Most common interactions experienced by people in long term use of Lamictal Xr, Celexa:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Drug Interaction | 10 |
| 2 | Encephalitis | 9 |
| 3 | Drug Toxicity | 9 |
| 4 | Convulsion | 9 |
| 5 | Thyroiditis | 8 |
| 6 | Malaise | 8 |
| 7 | Weight Increased | 6 |
| 8 | Psychotic Disorder | 6 |
| 9 | Sinus Tachycardia | 6 |
| 10 | Nausea | 6 |
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Top conditions involved for these people * :
- Depression
- Bipolar disorder
- Epilepsy
- Anxiety
- Convulsion
Top co-used drugs for these people * :
- Seroquel
- Aspirin
- Zyprexa
- Neurontin
- Klonopin
* Approximation only. Some reports may have incomplete information.
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Side effects in real world:
On eHealthMe, Celexa (citalopram hydrobromide) is often used to treat depression. Lamictal Xr (lamotrigine) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
Other drugs that are used to treat the same conditions:
Comments from related studies:
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I have a spontaneous clear sticky discharge from my left breast.
I forget words or cant instantly recall something, a hesitation in grabbing the right word
Kevin Peters Ph.d on Mar, 4, 2013:
Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
All the Best,
K. Peters
chris on Jun, 4, 2011:
i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.
TwoDimes on Apr, 15, 2012:
Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -
SammySushi on Jul, 10, 2012:
Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.
Christophe on Nov, 13, 2012:
Hello,
I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
from Christophe
AUDREY on Dec, 16, 2012:
STARTED TAKING DILTIAZEM 60 MG AND I AM VERY CONSTIPATED. 70 YEARS OLD, HEART SURGERY A FAST HEART RATE....
Sonya on Feb, 24, 2013:
You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.
Although some of the adverse outcomes tend to wax and wane as my mood shifts with bipolar disorder, the bed wetting is of extreme urgency. I'm looking for answers more for the bed wetting but would be happy to find reasons for the others as well.
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