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Review: Celexa and Savella

Summary: drug interactions are reported among people who take Celexa and Savella together.

This review analyzes the effectiveness and drug interactions between Celexa and Savella. It is created by eHealthMe based on reports of 75 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Celexa and Savella >>>

What are the drugs

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. (view latest outcomes from 30,706 users)

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 3,389 users)

On Dec, 17, 2014: 75 people who take Celexa, Savella are studied

Celexa, Savella outcomes

Drug combinations in study:
- Celexa (citalopram hydrobromide)
- Savella (milnacipran hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Celexa is effective0.00%
(0 of 1 people)
(0 of 3 people)
(0 of 2 people)
(0 of 1 people)
(1 of 1 people)
Savella is effective0.00%
(0 of 1 people)
(0 of 5 people)
(0 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Blood Pressure IncreasedTardive DyskinesiaVomitingCognitive DeteriorationHyperhidrosisHeadacheDizzinessSerotonin Syndrome
VomitingBlood Bilirubin IncreasedFibromyalgiaExtraocular Muscle ParesisAtrial TachycardiaHeadache
Serotonin SyndromeBlood Albumin DecreasedHypoaesthesiaHypertensionDyspnoeaHyperhidrosis
HeadacheAspartate Aminotransferase IncreasedMemory ImpairmentSelf Injurious BehaviorFeeling ColdBlood Pressure Increased
SomnolencePancreatitis AcuteBlood Pressure IncreasedTemperature IntoleranceHeart Rate IncreasedSuicidal Ideation
DizzinessMicrolithiasisMigraineMood ChangesHot FlushCompleted Suicide
MalaiseAlanine Aminotransferase IncreasedVision BlurredRapid Heart BeatDrug Toxicity
Hot FlushLiver Function Test AbnormalTremorChest PainExtrapyramidal Disorder
Heart Rate IncreasedBlood Glucose IncreasedRashSuicidal ThoughtsNausea
FrustrationHiatus HerniaBlisterMalaise

Drug effectiveness by gender :

Celexa is effective14.29%
(1 of 7 people)
(0 of 1 people)
Savella is effective14.29%
(1 of 7 people)
(0 of 1 people)

Most common drug interactions by gender * :

HeadacheSerotonin Syndrome
HyperhidrosisExtrapyramidal Disorder
Blood Pressure IncreasedMydriasis
Suicidal IdeationChest Discomfort
Completed SuicideDyskinesia
Chest PainDyspnoea
Serotonin SyndromeFaecaloma
Heart Rate IncreasedHyperhidrosis
Drug ToxicityHeadache
NauseaMultiple Drug Overdose Intentional

Drug effectiveness by age :

Celexa is effectiven/an/an/an/a0.00%
(0 of 10 people)
(0 of 2 people)
(1 of 2 people)
Savella is effectiven/an/an/an/a8.33%
(1 of 12 people)
(0 of 2 people)
(0 of 1 people)

Most common drug interactions by age * :

n/an/an/aExtrapyramidal DisorderSerotonin SyndromeVomitingHeadacheHeadache
Serotonin SyndromeDrug Screen PositiveFibromyalgiaCompleted SuicideHeart Rate Increased
MydriasisUrticariaHypoaesthesiaHyperhidrosisBlood Pressure Increased
DyskinesiaHyperhidrosisMemory ImpairmentDrug ToxicityHot Flush
LaryngospasmWeight IncreasedAngerChest DiscomfortDizziness
Psychomotor HyperactivityBlood Pressure IncreasedPneumoniaSkin InfectionNausea
Loss Of ConsciousnessDizzinessMigraineMalaiseBack Pain
Multiple Drug Overdose IntentionalFeeling HotVision BlurredSuicidal IdeationTension Headache
Impulsive BehaviourOedemaTremorFatigueHyperhidrosis
Drug ToxicityDrug Screen False PositiveBlood Pressure IncreasedSerotonin SyndromeMuscle Spasms

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Celexa and Savella?

You are not alone! Join a related mobile support group:
- support group for people who take Celexa and Savella
- support group for people who take Celexa
- support group for people who take Savella

Can you answer these questions (Ask a question):

More questions for: Celexa, Savella

You may be interested at these reviews (Write a review):

  • Citalopram seizures in my 13 year old daughter
    My daughter just turned 13. Her Father died last year and she was having trouble dealing with it so her doctor put her on 20 mil of citalopram once a day. She started feeling better in about a week. About 30 days later she had a severe seizure and quit breathing. I did CPR and got her breathing again and the paramedics took her to the hospital. After an MRI and EEG they sent her home and said keep an eye on her. She had about 6 seizures all together. I wouldn't let her out of my sight. Finally on her last trip to the hospital after having a seizure I again asked could it be the meds and the ER doc said yes so we took her off of it and no more seizures. It's been 4 weeks now and I'm hopeful that we found the problem. My daughter had never had any health problems... Be very careful what kind of meds you put your children on. Thank God she was home with me that night.
  • Drug interractions savella. amoxicillin
    Sudden ache, pain and neuropathy in right hand and wrist within 8 hours of sterting Amoxicillin.
  • Nausea and vomiting while taking savella
    I have been on Savella for 6 months now and the nausea has increased with time and now I also have vomiting daily along with occasional diarrhea. I am currently weaning off of the Savella, cutting the dosage in half for two weeks and then one pill every other day for two weeks, following my dr.'s instructions. I have three weeks total left and still have the nausea and vomiting but hopeful that these will start to go away soon. Anyone else who has weaned off of it- how long until your symptoms subsided?
  • Long-term use of risperidone and antidepressants
    I have been using Risperdal and antidepressants for 14 years for bipolar disorder. Last month I was diagnosed with adrenal insufficiency and progesterone deficiency. My cholesterol suddenly became high, I was tired all the time and more symptoms relating to my eventual diagnosis of adrenal insufficiency and progesterone deficiency. I must also say that at the same time of starting treatment I stopped using birth control pills. I feel there needs to be caution taken in all of these drugs. They seem to have a severe effect on hormone balance in the body.
  • So sleepy with savella
    I am just finishing the starter pack of Savella and I am so sleepy I can't hold my head up. My pain and other Fibromyalgia symptoms are tremendously better but I am sleeping like crazy. Hopefully I can have both doses at night and this will help. I am so glad to not be in pain but I need to be awake also. I am going to talk to my doctor about perhaps another medication to help curb the sleepiness. I can't use caffeine or stimulants due to anxiety but need something to take this sleepiness away.

More reviews for: Celexa, Savella

Comments from related studies:

  • From this study (7 months ago):

  • Have had a headache for three days


  • From this study (3 years ago):

  • I was aware that Savella might cause blurred vision, but am shocked and... incredibly frustrated that the single most helpful ("legal") drug in my battle against fibro is causing such rapid deterioration of my eyesight. In June of 2010, I tested OU(Both eyes) 20/20. within the first couple of months,I experienced the "blurred vision," and not long after awoke to complete blackness. Throughout the day, it slowly returned. My vision began to "come and go," eventually becoming unreliable and requiring glasses. My initial Rx, in November of 2010, was (R eye)od -.75 and -1.0 OS (L eye). Currently, my lenses are (R)od -1.25 and -1.75 OS(L), and are no longer adequate.


  • From this study (4 years ago):

  • Laurie Rogers on Dec, 1, 2010:

    I was put on both of these drugs in October and November of 2010 and suffered from Serotonin Syndrome. I have since been taken off of both. The worst part of the entire ordeal
    was that I was never warned of the risks by my doctor when she handed me the sample pack of Savella, which also did not contain the full prescribing information. A comedy of errors by other people that caused me a lot of unnecessary suffering. I never would have agreed to take this kind of risk because I had just begun treatment, and my doctor and I had not even explored other options.


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Complete drug side effects:

On eHealthMe, Celexa (citalopram hydrobromide) is often used to treat depression. Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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