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Review: taking Clindamycin and Coumadin together

Summary: drug interactions are reported among people who take Clindamycin and Coumadin together.

This review analyzes the effectiveness and drug interactions between Clindamycin and Coumadin. It is created by eHealthMe based on reports of 815 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Clindamycin hydrochloride has active ingredients of clindamycin hydrochloride. It is often used in infection. (latest outcomes from 1,328 Clindamycin hydrochloride users)

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from 75,111 Coumadin users)

On Feb, 11, 2015: 815 people who take Clindamycin Hydrochloride, Coumadin are studied

Clindamycin Hydrochloride, Coumadin outcomes

Drug combinations in study:
- Clindamycin Hydrochloride (clindamycin phosphate)
- Coumadin (warfarin sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Clindamycin Hydrochloride is effective50.00%
(1 of 2 people)
Coumadin is effectiven/a0.00%
(0 of 1 people)
(1 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
International Normalised Ratio IncreasedInjuryDeathn/aPulmonary HaemorrhageDepressionErectile DysfunctionPain
PneumoniaPulmonary InfarctionRespiratory FailurePainAnxiety
RashPyrexiaPneumonia AspirationAttention Deficit/hyperactivity DisorderOsteonecrosis Of Jaw
PyrexiaPainHaemoptysisPulmonary EmbolismInjury
Platelet Count DecreasedPulmonary EmbolismConvulsionEmotional DistressAnaemia
Renal Failure AcuteChest PainDepressed Level Of ConsciousnessAnxietyOsteomyelitis
ArrhythmiaMelaenaCondition AggravatedPanic DisorderOsteoarthritis
SepsisConfusional StatePain In Jaw
Haematocrit DecreasedCoagulation Time ProlongedBone Disorder

Drug effectiveness by gender :

Clindamycin Hydrochloride is effectiven/a50.00%
(1 of 2 people)
Coumadin is effective0.00%
(0 of 1 people)
(2 of 2 people)

Most common drug interactions by gender * :

Osteonecrosis Of JawInjury
AstheniaOsteonecrosis Of Jaw
AnaemiaBone Disorder
Metastases To BoneSpinal Osteoarthritis
Pain In JawOsteomyelitis

Drug effectiveness by age :

Clindamycin Hydrochloride is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
(0 of 1 people)
Coumadin is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
(0 of 1 people)
(1 of 1 people)

Most common drug interactions by age * :

n/aInternational Normalised Ratio IncreasedTremor NecCompleted SuicideFracture NonunionPainPainPain
DeathRigorsPulmonary EmbolismFatigueOedema PeripheralAnxietyAnaemia
PetechiaeFeeling ColdChest PainGastrooesophageal Reflux DiseaseOsteonecrosis Of JawOsteonecrosis Of JawAnxiety
Multi-organ FailureBone PainPainGingivitisAnxietyAnaemiaOsteoarthritis
PainPulmonary InfarctionIron Deficiency AnaemiaTooth DisorderEmotional DistressInjury
AnxietyInjuryInjuryAbdominal PainPain In JawOsteonecrosis Of Jaw
FearDyspnoeaDyskinesiaDepressionDepressionBone Disorder
Renal FailureNauseaDisabilityMetastases To BoneNeuropathy PeripheralCardiac Failure Congestive
DepressionPulmonary Veno-occlusive DiseaseBone Callus ExcessiveBone DisorderBack PainOsteomyelitis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Clindamycin and Coumadin on

Do you take Clindamycin and Coumadin?

You are not alone! Join a related mobile support group:
- support group for people who take Clindamycin and Coumadin
- support group for people who take Clindamycin Hydrochloride
- support group for people who take Coumadin

Can you answer these questions (Ask a question):

More questions for: Clindamycin Hydrochloride, Coumadin

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More reviews for: Clindamycin Hydrochloride, Coumadin

Comments from related studies:

  • From this study (3 years ago):

  • Creekpaddler on Apr, 19, 2012:

    I just started taking Crestor 3 days ago after taking the last of my Clindimycin capsules. Following my first 20-mg dose on the evening of 4/16/12, I experienced only a decreased appetite during breakfast. But 5 hours after taking my second pill on 4/17 I woke up feeling nauseous, then I passed out in the bathroom and fell to the floor. I had never passed out in my life until then. And I was lucky - only sprained 2 toes. My wife heard me fall and took the day off to care for me. And it was one rough day with vomiting, diarrhea, and severe muscular weakness.

    I called the doctor and have been taken off Crestor. We don't know if Crestor caused all that. It could have been a GI virus, but I'm not sure I want to take a chance on another 20-mg dose or even a smaller dose - 10 mg or 5 mg. I don't know what to do at this point.


Complete drug side effects:

On eHealthMe, Clindamycin Hydrochloride (clindamycin phosphate) is often used to treat infection. Coumadin (warfarin sodium) is often used to treat blood clots. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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