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Review: Clindamycin and Methotrexate

This review analyzes the effectiveness and drug interactions between Clindamycin and Methotrexate. It is created by eHealthMe based on 305 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 1, 2014: 305 people who reported to have interactions when taking Clindamycin Hydrochloride, Methotrexate are studied

Trend of Clindamycin Hydrochloride, Methotrexate's drug interactions, side effects and effectiveness reports (4323647)

Drug combinations in study:
- Clindamycin Hydrochloride (clindamycin phosphate)
- Methotrexate (methotrexate sodium)

eHealthMe real world results:

Most common interactions experienced by people in the use of Clindamycin Hydrochloride, Methotrexate:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety305
Pain248
Pyrexia (fever)237
Anaemia (lack of blood)208
Osteomyelitis (infection of bone)208
Osteonecrosis Of Jaw (death of bone of jaw)202
Oedema Peripheral (superficial swelling)190
Osteoarthritis (a joint disease caused by cartilage loss in a joint)168
Bone Disorder144
Pleural Effusion (water on the lungs)140

Most common interactions experienced by people in long term use of Clindamycin Hydrochloride, Methotrexate:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Arthritis Bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)17
Skin Lesion (redness)16
Skin Ulcer8
Spinal Column Stenosis (narrowing of spinal column)8
Skin Warm8
Oedema Peripheral (superficial swelling)8
Abscess (pus)8
Infective Myositis (infection of skeletal muscle)8
Purulent Discharge (discharge that contains pus)8
Intervertebral Disc Protrusion (spinal disc protrusion)8

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Clindamycin Hydrochloride0.000.000.000.000.00
Methotrexate0.00%0.00%100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis
  2. Pain
  3. Prophylaxis
  4. Osteoporosis
  5. Hypertension

Top co-used drugs for these people * :

  1. Prednisone
  2. Lasix
  3. Clindamycin hcl
  4. Zofran
  5. Folic acid

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Clindamycin Hydrochloride, Methotrexate

You can also:

Complete drug side effects:

On eHealthMe, Clindamycin Hydrochloride (clindamycin phosphate) is often used to treat infection. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

Can you answer these questions (what is this?):

More questions for: Clindamycin Hydrochloride, Methotrexate

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More reviews for: Clindamycin Hydrochloride, Methotrexate

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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