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Review: taking Clindamycin and Methotrexate together

Summary: drug interactions are reported among people who take Clindamycin and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Clindamycin and Methotrexate. It is created by eHealthMe based on reports of 308 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Clindamycin and Methotrexate >>>

What are the drugs

Clindamycin hydrochloride has active ingredients of clindamycin hydrochloride. It is often used in infection. (latest outcomes from 1,328 Clindamycin hydrochloride users)

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,243 Methotrexate users)

On Feb, 27, 2015: 308 people who take Clindamycin Hydrochloride, Methotrexate are studied

Clindamycin Hydrochloride, Methotrexate outcomes

Drug combinations in study:
- Clindamycin Hydrochloride (clindamycin phosphate)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Clindamycin Hydrochloride is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a
Methotrexate is effectiven/an/a0.00%
(0 of 1 people)
n/an/an/an/an/a

Drug effectiveness by gender :

FemaleMale
Clindamycin Hydrochloride is effectiven/a0.00%
(0 of 1 people)
Methotrexate is effectiven/a0.00%
(0 of 1 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Clindamycin Hydrochloride is effectiven/an/an/an/an/an/a0.00%
(0 of 1 people)
n/a
Methotrexate is effectiven/an/an/an/an/an/a0.00%
(0 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Acute Respiratory Distress SyndromeMyopathyBacteraemian/aLeukocytosisArthritis BacterialErythemaPain
PneumonitisMuscular WeaknessKidney RuptureImpaired Gastric EmptyingHypertensionOedema PeripheralAnxiety
Blood Bilirubin IncreasedLiver Function Test AbnormalArthritis BacterialVentilation/perfusion Scan AbnormalCatheter Site InfectionSkin LesionOsteomyelitis
PneumoniaLeukocytosisArthralgiaPleuritic PainOropharyngeal Cancer Stage UnspecifiedIntervertebral DiscitisAnaemia
HypotensionImpaired Gastric EmptyingPostpartum HaemorrhageDysuriaProgressive Multifocal LeukoencephalopathySkin WarmOsteonecrosis Of Jaw
AnaemiaVentilation/perfusion Scan AbnormalDiarrhoeaCholelithiasisPharyngeal InflammationInfective MyositisOedema Peripheral
NeutropeniaPleuritic PainAbortion SpontaneousBlood Culture PositiveStaphylococcal InfectionIntraspinal AbscessOsteoarthritis
Febrile NeutropeniaDysuriaZygomycosisAcute SinusitisAbscessPyrexia
HiccupsCholelithiasisUterine CancerVenous Thrombosis LimbPurulent DischargeBone Disorder
Aspartate Aminotransferase IncreasedZygomycosisJoint EffusionHypertensive CrisisIntervertebral Disc ProtrusionPleural Effusion

Most common drug interactions by gender * :

FemaleMale
PainFebrile Neutropenia
AnxietyAscites
OsteomyelitisRenal Failure
AnaemiaNeutropenia
Osteonecrosis Of JawStaphylococcal Infection
Oedema PeripheralSkin Ulcer Nos
OsteoarthritisStridor
PyrexiaStevens Johnson Syndrome
Tooth ExtractionAngioneurotic Oedema
Bone DisorderAsthenia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Renal HypertrophyAscitesPneumonitisNeutropeniaPyrexiaPainPleural EffusionAnxiety
Bladder DiverticulumStevens Johnson SyndromeAcute Respiratory Distress SyndromePneumonia BacterialDermatitis NosAnaemiaPainPain
Clostridial InfectionStridorHypotensionPseudomembranous ColitisAcute Circulatory FailureOedema PeripheralLung DisorderTooth Extraction
Reflux NephropathySkin Ulcer NosBlood Bilirubin IncreasedThrombocytopeniaBlisterAnxietyRenal FailureAnaemia
Palatal DisorderAngioneurotic OedemaLung InfectionHypokalaemiaPruritusOsteonecrosis Of JawOsteopeniaOsteomyelitis
Respiratory Syncytial Virus InfectionBlisterFebrile NeutropeniaRenal ImpairmentStevens Johnson SyndromeBronchitisSinusitisMetastases To Bone
Urinary Tract InfectionStomatitisScedosporium InfectionHiccupsEpidermal NecrolysisHeadacheEnterococcal InfectionOsteoarthritis
Oedema NosEncephalitis FungalAnaemiaWhite Blood Cell Count DecreasedSinusitisSepsisDeep Vein Thrombosis
Mucosal Inflammation NosHypernatraemiaDeep Vein ThrombosisBlood Pressure IncreasedOsteomyelitisOedema PeripheralOsteonecrosis Of Jaw
PyrexiaPneumonia Respiratory Syncytial ViralPneumoniaChest PainInjurySwellingFibromyalgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Clindamycin and Methotrexate on

Do you take Clindamycin and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Clindamycin and Methotrexate
- support group for people who take Clindamycin Hydrochloride
- support group for people who take Methotrexate

Can you answer these questions (Ask a question):

  • Can you take advil and cleocin together? for the sinus infection
    Can you take advil and Cleocin Together? Have really bad pain to the left ear. Need something to take away the pain
  • I injected suboxone and now i feel weird this is not the first time i done it but the first time my arm is numb all over dizziness purple pinkish splotches all over my arm wat is wrong
    I shot an eighth of suboxone today and now my arm is purplish and red blotches there was no pain during or after injection only numbness dizziness and I can't get my nail nd to go to white it stays red this has never happened before.
  • Does clindamycin cause confusion and halucinations?
    Husband has dental infection, getting an implant. Since starting Clindomycin Tuesday has been getting more and more confused, can't do simple math, is imagining things, seeing and hearing things and is restless, can't sleep.
  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Would the tinnitus abate with if i discontinue methotrexate?
    I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste

More questions for: Clindamycin Hydrochloride, Methotrexate

You may be interested at these reviews (Write a review):

  • Muscle weakness from methotrexate
    I'm 61 and have taken methotrexate for 25 yrs. I've always done well with my blood results etc. Lately I've been having problems pushing a grocery cart. My arm muscles are so weak!
  • Having leg cramps after 2 years on enbrel
    Started having leg cramps after using Enbrel for almsot 2 years. They start the day I give the injection and have lasted 1-3 days waking me several time in the middle of the night.
  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Clindamycin - vertigo and nausea
    2 days in after starting on clendamycin for tooth infection I began having slight vertigo which steadily increased the next day. Nausea present with vomiting. I saw primary doc & I mentioned I was on this antibiotic which was told this could be the source of my problem and to stop taking medicine & consult w/my dentist. I have had 2 slight incidences with vertigo in the last 6 mos. which I assumed was happening not realizing it could be the clendamycin. I do not remember reading this interaction in the enclosed directions. Symptoms have pretty much resolved by today. I believe it was the clendamycin that caused this but have not hard proof

More reviews for: Clindamycin Hydrochloride, Methotrexate

Comments from related studies:

Complete drug side effects:

On eHealthMe, Clindamycin Hydrochloride (clindamycin phosphate) is often used to treat infection. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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