Review: taking Clonazepam and Zopiclone together
Summary: drug interactions are reported among people who take Clonazepam and Zopiclone together.
This review analyzes the effectiveness and drug interactions between Clonazepam and Zopiclone. It is created by eHealthMe based on reports of 1,034 people who take the same drugs from FDA and social media, and is updated regularly.
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Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 41,315 Clonazepam users) Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. (latest outcomes from 7,101 Zopiclone users)
What are the drugs
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 41,315 Clonazepam users)
Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. (latest outcomes from 7,101 Zopiclone users)
On Jan, 1, 2015: 1,034 people who take Clonazepam, Zopiclone are studied
Drug combinations in study:
- Clonazepam (clonazepam)
- Zopiclone (eszopiclone)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Clonazepam is effective||27.27%|
(3 of 11 people)
(5 of 19 people)
(4 of 11 people)
(6 of 8 people)
(6 of 15 people)
(5 of 9 people)
(3 of 6 people)
(0 of 1 people)
|Zopiclone is effective||8.33%|
(1 of 12 people)
(8 of 20 people)
(4 of 8 people)
(5 of 8 people)
(8 of 17 people)
(3 of 9 people)
(1 of 3 people)
(0 of 1 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Insomnia||Insomnia||Insomnia||Emotional Distress||Anxiety||Abdominal Distension||Abdominal Pain||Insomnia|
|Drug Ineffective||Dysgeusia||Fatigue||Depression||Urinary Retention||Abdominal Pain||Gallbladder Disorder||Drug Ineffective|
|Dysgeusia||Drug Ineffective||Depression||Hypersexuality||Gastric Disorder||Change Of Bowel Habit||Mental Disorder||Depression|
|Initial Insomnia||Abnormal Dreams||Drowsiness||Obsessive-compulsive Personality Disorder||Dry Mouth||Abdominal Pain Upper||Cholelithiasis||Anxiety|
|Middle Insomnia||Anxiety||Initial Insomnia||Suicidal Ideation||Migraine||Biliary Dyskinesia||Abdominal Bloating||Dysgeusia|
|Somnolence||Nightmare||Roseola||Pathological Gambling||Memory Impairment||Diarrhoea||Cancer Pain||Headache|
|Anxiety||Suicide Attempt||Abnormal Dreams||Biliary Tract Disorder||Nocturnal Fear||Biliary Tract Disorder||Tiredness||Weight Increased|
|Dizziness||Middle Insomnia||Acid Reflux||Pain||Creatinine Renal Clearance Decreased||Dyspepsia||Dyspnoea|
|Agitation||Initial Insomnia||Delusion||Abdominal Pain||Chest Pain||Nausea||Fatigue|
Drug effectiveness by gender :
|Clonazepam is effective||36.84%|
(21 of 57 people)
(11 of 23 people)
|Zopiclone is effective||38.60%|
(22 of 57 people)
(8 of 21 people)
Most common drug interactions by gender * :
|Drug Ineffective||Drug Ineffective|
|Headache||Type 2 Diabetes Mellitus|
Drug effectiveness by age :
|Clonazepam is effective||n/a||n/a||0.00%|
(0 of 1 people)
(5 of 22 people)
(8 of 35 people)
(9 of 50 people)
(7 of 48 people)
(3 of 9 people)
|Zopiclone is effective||n/a||n/a||100.00%|
(1 of 1 people)
(5 of 21 people)
(5 of 35 people)
(8 of 49 people)
(8 of 48 people)
(3 of 9 people)
Most common drug interactions by age * :
|n/a||n/a||Anxiety||Muscle Spasms||Drug Ineffective||Insomnia||Insomnia||Insomnia|
|Depression||Drug Abuse||Weight Increased||Dysgeusia||Drug Ineffective||Drug Ineffective|
|Insomnia||Joint Sprain||Anxiety||Drug Ineffective||Dysgeusia||Middle Insomnia|
|Back Pain||Vaginal Discharge||Insomnia||Headache||Depression||Pain|
|General Physical Health Deterioration||Abdominal Pain Upper||Dizziness||Weight Increased||Anxiety||Fatigue|
|Pregnancy||Abdominal Pain||Diabetes Mellitus||Fatigue||Fatigue||Headache|
|Cholecystitis Chronic||Chest Discomfort||Nausea||Chest Pain||Dyspnoea||Dizziness|
|Emotional Distress||Suicidal Ideation||Decreased Appetite||Type 2 Diabetes Mellitus||Nausea||Anxiety|
|Suicide Attempt||Dyspnoea||Dysgeusia||Diabetes Mellitus||Fall||Dysgeusia|
|Incision Site Infection||Asthenia||Overdose||Depression||Pain||Pain In Extremity|
* Some reports may have incomplete information.
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Can you answer these questions (Ask a question):
- Can you stop trileptal cold turkey?
I ran outta my Trileptal, the last time I took it was in the hospital on Saturday I was there for 2 days and I was normally taking 300mg 2x daily and the hospital gave me 600mg 4x on Saturday and the day before I took the one 300mg I had left in the morning. Since the hospital I have not had any Trileptal to be able to take because they didn't send me home with any because I'm from another State and I'm not sure if that's why but I should have my medicine tomorrow but I feel horrible and I just wanna know if physically I will be alright? Thank you so much and would appreciate a quick responce.
- I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal
- What is residual biloma egfr60
had accident at work,ruptured spleen,removed gall bladder,massive livery trauma.received blood transfusion stabilised haemodynamically ,sustained acute kidney injury also recieved inotropic support.
- Can i take cialis and klonopin
I've been taking klonopin and it's making it hard for me to have an erection. Can I take cialis while on klonopin?
- Can i take a 3mg lunesta and a 30mg temazapam together? the lunesta does not work at all.
I really need to find out because I can't get any sleep .I thought since the lunesta doesn't work then I can take a 30mg temazapam to help I have severe insomnia. Please answer! !
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I was diagnosed with nasal polyps and put on Flonase (a steroid nose spray). It worked well to dry up post-nasal drip but I ended up with a bad case of panic and fear. I had overcome episodes of these nervous disorders but the Flonase brought it all back. I still suffer from panic even though I stopped the Flonase months ago. I had a bad attack on a bridge and also inside a grocery store. Personnel had to take me to the store office to calm me down. I am nearly agoraphobic now. I do go out alone but try to avoid after-dark. My life has been turned into daily dread of another attack. To think that I was more than ten years FREE of panic until I took the Flonase makes me feel so regretful that I ever took that stuff. It should be banned as there is enough evidence to do so from many people who now suffer debilitating and recurring panic.
- A life of depression and fatigue (1 response)
1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
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- 3 strong drugs together against neuropathic pain
Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
- Sepsis hallucinations misdiagnosed
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I thought the sculpture had won the Nobel prize, and the book was the biography of the sculptor, whose mother had gone to extraordinary lengths to keep him safe from the Nazis. Some may actually have occurred during dreams, and were wildly improbable, but I don't recall ever going to sleep. At one point, I thought I was at a rest stop on the NJ turnpike, and saw the Nobel-winning sculptor there, working on a wood sculpture. The sculptor turned out to be the maintenance man on the hospital floor. I pulled out the naso-gastral tube three times, but was unaware that I had done so, although I do remember believing that I was buried beneath peat moss and feeling suffocated as I clawed my way out. I also thought I was at a party being given by a law firm which had sold its building to a school for gifted children, but I (also a lawyer) had been deposited there by my nurse and her boyfriend, who were supposed to have taken me to the OR. Some scenes from a book I had been reading made their way into my delusions, which were so real to me that I actually called some of the people involved later on and asked if the events had really happened. The hallucinations began before surgery and continued afterward. When I awoke from anesthesia, I thought the hospital staff was painting the doors to my upstairs bathroom, a project I'd been involved with before the blockage struck. I asked them how they knew what colors to use. They thought I was joking, and confirmed that they had gotten the colors right. Finally a neurologist was summoned, and I told her I was on the passenger ramp at La Guardia airport (instead of in a hospital in NC), and that I'd been born in Havana, Cuba (instead of Baltimore, MD.) I believed myself to be a member of the ruling party in Cuba (pre-Castro) and during an outdoor ceremony, an earthquake had struck, causing ancient monuments to come tumbling down. 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Hallucinations occur in only a very small percentage of sepsis sufferers, and in only a small percentage of those withdrawing suddenly from clonazepam. However, I do fit the profile of those who do experience hallucinations with sepsis, being female and aged 62 at the time of this description. After the three-day period, I returned to normal, although believing that my hallucinations had been real persisted for some days afterward. I recovered quickly from the surgery, although the pain persisted for a while, and I was walking easily (dragging my IV with me) through the hospital halls. This was the ONLY symptom I had. Not all the hallucinations were unpleasant -- in fact, they were highly interesting -- but they were incredibly complex. I still remember all the details, better than I remember what actually happened yesterday. Except for the urinary-tract infection, I had no other adverse effects from hospitalization -- no fever, chills, nausea, sweating, headaches, trembling or anything of that kind. The bowel blockage and the surgery were of course not fun, but in a way the hallucinations were fascinating. My own feeling, and that of the doctors who know me and my medical issues, is that my experiences were caused by sepsis, not clonazepam withdrawal, and the antibiotics I was given are probably what saved me.
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Complete drug side effects:
On eHealthMe, Clonazepam (clonazepam) is often used to treat stress and anxiety. Zopiclone (eszopiclone) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Clonazepam is used in:
- Zopiclone is used in:
Other drugs that are used to treat the same conditions:
- Clonazepam alternatives:
- Zopiclone alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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