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Review: Clonidine and Sertraline

This review analyzes the effectiveness and drug interactions between Clonidine and Sertraline. It is created by eHealthMe based on 685 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

On Mar, 29, 2014: 685 people who reported to have interactions when taking Clonidine, Sertraline are studied

Trend of Clonidine, Sertraline's drug interactions, side effects and effectiveness reports (7390764)

Drug combinations in study:
- Clonidine (clonidine)
- Sertraline (sertraline hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Clonidine, Sertraline:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety685
Dyspnoea (difficult or laboured respiration)471
Pain440
Vomiting363
Arthralgia (joint pain)342
Depression306
Injury298
Fatigue (feeling of tiredness)281
Nausea (feeling of having an urge to vomit)276
Headache (pain in head)232

Most common interactions experienced by people in long term use of Clonidine, Sertraline:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety9
Postoperative Wound Complication8
Breast Cyst8
Breast Cancer Female8
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)6
Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)4
Pancreatitis (inflammation of pancreas)4
Affective Disorder (mental disorder)4
Stereotypy (excessive repetition or lack of variation in movements, ideas, or patterns of speech)4
Constipation4

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Clonidine0.00%40.00%0.00%40.00%20.00%
Sertraline0.00%0.00%50.00%50.00%0.00%

Top conditions involved for these people * :

  1. Depression
  2. Hypertension
  3. Anxiety
  4. Pain
  5. Nuclear magnetic resonance imaging

Top co-used drugs for these people * :

  1. Seroquel
  2. Zoloft
  3. Heparin sodium injection
  4. Aspirin
  5. Magnevist

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Clonidine, Sertraline

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Complete drug side effects:

On eHealthMe, Clonidine (clonidine) is often used to treat high blood pressure. Sertraline (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 weeks ago):

  • Vyvanse is my most recently prescribed ADD medication, but I have been on various other prescriptions since the age of 9. (Adderall at first for a short time [< 1 month], stopped because it caused severe panic attacks; Concerta in increasing doses over the next 5 years, but never more than 72mg; Vyvanse for the past 3 years, at 60mg for two years, moved up to 70mg last year). Already had trouble falling asleep; when I started taking these stimulants, it became full blown insomnia, requiring prescription of Clonidine (started at .1mg, has increased to .2mg). During the school day all symptoms are managed very well- no trouble focusing, less impulsiveness, more self-control. After Vyvanse wears off (normally seven and a half to eight hours after ingestion), all symptoms of ADD return in full force. A few years ago I was diagnosed with Panic Disorder (without Agoraphobia) when I started getting frequent panic attacks. I was prescribed Hydroxyzine Pamoate 50mg, which I take whenever I feel a panic attack coming on. I had problems with asthma and acid reflux problems since my birth, and the asthma became very severe. I spent much time in the NICU when I was born, and I had to be rushed to the hospital several times in the first few years of my life. I used to carry an inhaler everywhere, but at the age of 10, 3 years after my last major problem with asthma, my physician and I decided that I had successfully overcome my problems with asthma (insofar as one can overcome such problems- in any case, I haven't had a problem with it in nearly a decade. The acid reflux recently returned, but with very low severity. The only problems I've had with it recently are occasionally waking up with feelings of heartburn and acid rising in my chest. My physician told me to take one dose of over-the-counter Pepcid Complete before bed, and that has remedied all problems with the acid reflux. Last year I was diagnosed with Major Depressive Disorder, and prescribed Sertraline.
    When I started the ADD stimulants, I had large weight fluctuations, because during the day I had no appetite, but at night I was very hungry. My weight stayed within a range of approximately 40lbs, but there would be months when I gained a lot of weight quickly, and others when I would lose weight just as quickly.
    When my workload increased as I began High School, even with a boost in Vyvanse dosage, I found it hard to get all my work done without staying up all night.
    I once procrastinated on a project and wound up a week away from the due date with very little done. I stopped taking my Clonidine, and started taking extra Vyvanse and drinking several cups of coffee a day (approx. 10 a day) so I could stay up several nights in a row. After not sleeping from Monday morning to Thursday afternoon, the sleep deprivation resulted in severe bruxism, clicking of my tongue at the back of my teeth uncontrollably, dry mouth, dizziness, rapid heart rate, and eventually auditory hallucinations and syncope. Since then I have not done anything as reckless as abusing stimulants to stay awake.
    In times of high stress (the week before opening night for the school musical, for example), I develop an uncontrollable muscle twitch, primarily in my left shoulder but occasionally in my right hand, both at varied and unpredictable intervals. The hand twitch can be very noticeable and very disruptive, especially if it persists for more than a minute. The shoulder twitch is less noticeable, but once acknowledged, it becomes more severe. I have tried holding the limb down, but the only thing that works is riding it out. Never has a single period of muscle twitching exceeded 4 minutes.

    Reply

  • From this study (10 months ago):

  • Have had leaking right breast occasionally during peri-menopausal years. Just noticed same clear yellow liquid in same (right) breast. No pain, lumps, swelling, redness, etc., but the liquid is darker. Should I be concerned?

    Reply

  • From this study (10 months ago):

  • I have had occasional nipple discharge thru peri-menopausal years, always in my right breast only and always a yellowish clear color. I have not had a period in 7 months, so I'm pretty sure this is indicitive of full Menopause. I just noticed some leakage in same breast (right),still clear but a darker shade of yellow. There has never been any pain,lumps, swelling or redness, etc., involved. Should I be concerned about the color getting darker?

    Reply

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Can you answer these questions (what is this?):

  • After being on zoloft (sertraline) for 19 years, i now notice multiple side effects and i want to get off
    I have been on Zoloft (sertraline) for 19 years for chronic depression. When I first started taking Zoloft, it made a huge positive impact on my life. It was a miracle drug for me. I believe it saved my life. Ten or so years ago it suddenly stopped working. My doctor had me try several other S ...

  • Does taking zoloft cause you to shoplift?
    Have been taking 200mg zoloft for anxiety/ depression for a few years now, anxiety is under control and depression but I am now shoplifting, my finances are okay ? I go into a trance and don't care and shoplift items I can afford and don't really need, I feel so bad after doing it, I don't have a cr ...

  • Is it safe to take pravastin while on remicade?
    I have just started on Remicade and this drug scares the heck out of me! However it is being used as a last resort as no other medications were bring my ulcerative colitis under control I am very concerned about drug interactions and can't seem to get any straight answers from my doctor or the pha ...

More questions for: Clonidine, Sertraline

You may be interested at these reviews (what is this?):

  • Zoloft & klonipin created a horrible psychosis
    Causes psychosis, bipolar anxiety and seizures. Violence happens on all psychiatric drugs. Curing psychosis and deafness took the complete abandonment of psychiatry.

  • Steven-johnsons syndrome caused by zoloft
    Was diagnosed with depression start of last year due to my Aspergers multiplying school pressures for me. I was not put on any medication until 4 weeks ago. I was put on Zoloft 25mg, which slowly increased to 50mg. The moment I started on 50mg it caused severe lip dryness leading to cracking of the ...

  • Heart pounding on zoloft
    Have been on Zoloft for 3 weeks and have heart pounding once a week for a few hours which unable me to sleep

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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