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Review: Clonidine and Sertraline





Summary: drug interactions are reported among people who take Clonidine and Sertraline together.

This review analyzes the effectiveness and drug interactions between Clonidine and Sertraline. It is created by eHealthMe based on reports of 703 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Clonidine and Sertraline >>>

What are the drugs

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. (latest outcomes from Clonidine 9,662 users)

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. (view latest outcomes from 26,447 users)

On Dec, 14, 2014: 703 people who take Clonidine, Sertraline are studied

Clonidine, Sertraline outcomes

Drug combinations in study:
- Clonidine (clonidine)
- Sertraline (sertraline hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Clonidine is effective0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
100.00%
(1 of 1 people)
0.00%
(0 of 3 people)
71.43%
(5 of 7 people)
n/a50.00%
(1 of 2 people)
Sertraline is effective0.00%
(0 of 1 people)
20.00%
(1 of 5 people)
0.00%
(0 of 5 people)
100.00%
(1 of 1 people)
33.33%
(1 of 3 people)
33.33%
(1 of 3 people)
100.00%
(3 of 3 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
SepsisSomnolenceType 2 Diabetes MellitusPriapismBreast Cancer FemaleExhaustion, Fatigue, Lethargy, Tiredness, WearinessExhaustion, Fatigue, Lethargy, Tiredness, WearinessAnxiety
NeutropeniaVomitingBlood Cholesterol IncreasedChronic PainBreast CystDiverticulumLose WeightPain
Respiratory FailureHyperhidrosisObesityPostoperative Wound ComplicationDuodenitisWeight IncreasedDyspnoea
Multi-organ FailureWeight IncreasedHyperlipidaemiaFatigueGastritis ErosiveAllergiesDepression
ThrombocytopeniaWithdrawal SyndromeBlood Triglycerides IncreasedPainCoronary Artery DiseaseHyperkalaemiaNausea
AcidosisThrombocytopeniaPanic AttacksMental DisorderCataractImpotenceInjury
Cerebrovascular AccidentSepsisStress And AnxietyGallbladder InjuryCardiac Failure CongestiveEjaculation DelayedFatigue
DepressionRespiratory FailureCraniocerebral InjuryCholecystitis ChronicGastrointestinal HaemorrhageAutism Spectrum DisorderHeadache
AnhedoniaNeutropeniaDyslipidaemiaEmotional DistressColitisConstipationVomiting
FearExtrapyramidal DisorderGlaucomaMusculoskeletal DiscomfortHypertonic BladderDiabetic KetoacidosisAsthenia

Drug effectiveness by gender :

FemaleMale
Clonidine is effective36.36%
(4 of 11 people)
44.44%
(4 of 9 people)
Sertraline is effective25.00%
(3 of 12 people)
44.44%
(4 of 9 people)

Most common drug interactions by gender * :

FemaleMale
PainAnxiety
AnxietyDizziness
DepressionBack Pain
NauseaPain
DyspnoeaHeadache
InjuryBronchitis
Pain In ExtremityTremor
ArthralgiaSomnolence
Muscular WeaknessDyspnoea
HypoaesthesiaCardiac Failure Congestive

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Clonidine is effectiven/a0.00%
(0 of 1 people)
27.27%
(3 of 11 people)
0.00%
(0 of 4 people)
0.00%
(0 of 1 people)
25.00%
(1 of 4 people)
44.44%
(4 of 9 people)
0.00%
(0 of 6 people)
Sertraline is effectiven/a0.00%
(0 of 1 people)
20.00%
(2 of 10 people)
11.11%
(1 of 9 people)
0.00%
(0 of 1 people)
25.00%
(1 of 4 people)
33.33%
(3 of 9 people)
0.00%
(0 of 6 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Pancreatitis AcuteWeight IncreasedAggressionRenal Failure AcuteAnxietyPainPainHypotension
DyspnoeaPancreatitisCerebrovascular AccidentHypertensionAnxietyOedema PeripheralVomiting
SomnolenceDiabetic KetoacidosisAnxietyType 2 Diabetes MellitusDepressionAnxietyNausea
TachypnoeaType 1 Diabetes MellitusVomitingBack PainPain In ExtremityDepressionDehydration
VomitingSuicidal IdeationMalaiseHeadacheNeuropathy PeripheralMobility DecreasedAsthenia
Cardio-respiratory ArrestAbnormal BehaviourAbdominal PainDyspnoeaInjuryNauseaDiarrhoea
Blood Pressure DecreasedAnxietyDepressionPainDyspnoeaFallPain
DystoniaDeathConvulsionPanic AttackSpinal OsteoarthritisArthralgiaPneumonia
EnuresisAkathisiaChest PainChest PainArthralgiaDyspnoeaDizziness
HyperhidrosisAgitationBlood Pressure FluctuationEmotional DistressOsteonecrosis Of JawDeformityHypertension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Clonidine and Sertraline?

You are not alone! Join a related mobile support group:
- support group for people who take Clonidine and Sertraline
- support group for people who take Clonidine
- support group for people who take Sertraline

Can you answer these questions (Ask a question):

More questions for: Clonidine, Sertraline

You may be interested at these reviews (Write a review):

  • Loss of menstruation
    Hi
    I stopped using setralin 50 µg in August 2014. (I have been taken it in 1 year for my PMS). After stopping taking the pills my period become very short in september and then desappeard. I got a funcional cyste (about 30 mm) and after 10-days treatment with progesterone I got my period in the end of oktober. Two weeks afterwards I got a spare bleeding and my gyn thought that it my be an ovulation bleeding. Anyhow I have not got my period yet. The samples taken in oktober showed low FSH and heigt E2. The doctor explained that it is posible that stopping setralin could cause this hormonal imbalance. I must say that my periods were not so regular for very long time like during that year with setralin but I had other side effects like problem with concentartion, nussea etc.
    For many years ago I was on Zoloft but I had not experienced the same problem. When I started the treatment this time they did not want to give me zoloft (because of the price). I had no choice but i experienced many symptoms from different generica of Setralin. I will meet my doctor om Monday again.
  • Soar throat after taking sertaline
    half a pill first timw. severe soar throat 2 hrs after taking 25mg
  • Miscarriage 6 weeks while on sertraline
    On sertraline 150 mg a day, alcohol (1+ drink a day) and high caffeine. Sertraline lowered to 100mg when 4.5 weeks pregnant, no alcohol no caffeine. Miscarried at 6 weeks.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Laryngitis and fluconazole
    Occasionally when I have a severe yeast infection, I get laryngitis. I am so thankful your article addresses this, as the doctors I have seen were less than receptive when I suggested a link. I do not have any of the other health concerns listed in the study, but am taking fluconazole.

More reviews for: Clonidine, Sertraline

Comments from related studies:

  • From this study (5 months ago):

  • Upon taking the Clonidine & melatonin before bedtime, this 4 year old develops severe knee clicking which seems to hurt her upon falling asleep. If she gets angry during the day she can involuntarily start the knee clicking. She is very double jointed.

    Reply

  • From this study (10 months ago):

  • Vyvanse is my most recently prescribed ADD medication, but I have been on various other prescriptions since the age of 9. (Adderall at first for a short time [< 1 month], stopped because it caused severe panic attacks; Concerta in increasing doses over the next 5 years, but never more than 72mg; Vyvanse for the past 3 years, at 60mg for two years, moved up to 70mg last year). Already had trouble falling asleep; when I started taking these stimulants, it became full blown insomnia, requiring prescription of Clonidine (started at .1mg, has increased to .2mg). During the school day all symptoms are managed very well- no trouble focusing, less impulsiveness, more self-control. After Vyvanse wears off (normally seven and a half to eight hours after ingestion), all symptoms of ADD return in full force. A few years ago I was diagnosed with Panic Disorder (without Agoraphobia) when I started getting frequent panic attacks. I was prescribed Hydroxyzine Pamoate 50mg, which I take whenever I feel a panic attack coming on. I had problems with asthma and acid reflux problems since my birth, and the asthma became very severe. I spent much time in the NICU when I was born, and I had to be rushed to the hospital several times in the first few years of my life. I used to carry an inhaler everywhere, but at the age of 10, 3 years after my last major problem with asthma, my physician and I decided that I had successfully overcome my problems with asthma (insofar as one can overcome such problems- in any case, I haven't had a problem with it in nearly a decade. The acid reflux recently returned, but with very low severity. The only problems I've had with it recently are occasionally waking up with feelings of heartburn and acid rising in my chest. My physician told me to take one dose of over-the-counter Pepcid Complete before bed, and that has remedied all problems with the acid reflux. Last year I was diagnosed with Major Depressive Disorder, and prescribed Sertraline.
    When I started the ADD stimulants, I had large weight fluctuations, because during the day I had no appetite, but at night I was very hungry. My weight stayed within a range of approximately 40lbs, but there would be months when I gained a lot of weight quickly, and others when I would lose weight just as quickly.
    When my workload increased as I began High School, even with a boost in Vyvanse dosage, I found it hard to get all my work done without staying up all night.
    I once procrastinated on a project and wound up a week away from the due date with very little done. I stopped taking my Clonidine, and started taking extra Vyvanse and drinking several cups of coffee a day (approx. 10 a day) so I could stay up several nights in a row. After not sleeping from Monday morning to Thursday afternoon, the sleep deprivation resulted in severe bruxism, clicking of my tongue at the back of my teeth uncontrollably, dry mouth, dizziness, rapid heart rate, and eventually auditory hallucinations and syncope. Since then I have not done anything as reckless as abusing stimulants to stay awake.
    In times of high stress (the week before opening night for the school musical, for example), I develop an uncontrollable muscle twitch, primarily in my left shoulder but occasionally in my right hand, both at varied and unpredictable intervals. The hand twitch can be very noticeable and very disruptive, especially if it persists for more than a minute. The shoulder twitch is less noticeable, but once acknowledged, it becomes more severe. I have tried holding the limb down, but the only thing that works is riding it out. Never has a single period of muscle twitching exceeded 4 minutes.

    Reply

  • From this study (2 years ago):

  • Have had leaking right breast occasionally during peri-menopausal years. Just noticed same clear yellow liquid in same (right) breast. No pain, lumps, swelling, redness, etc., but the liquid is darker. Should I be concerned?

    Reply

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Complete drug side effects:

On eHealthMe, Clonidine (clonidine) is often used to treat high blood pressure. Sertraline (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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