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Review: Co-codamol and Ibuprofen

This review analyzes the effectiveness and drug interactions between Co-codamol and Ibuprofen. It is created by eHealthMe based on reports of 1,526 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Co-codamol and Ibuprofen >>>

What are the drugs

Co-codamol (latest outcomes from 235 users) has active ingredients of acetaminophen; codeine phosphate. It is often used in pain.

Ibuprofen (latest outcomes from 61,542 users) has active ingredients of ibuprofen. It is often used in pain.

On Sep, 11, 2014: 1,526 people who take Co-codamol, Ibuprofen are studied

Co-codamol, Ibuprofen outcomes

Drug combinations in study:
- Co-codamol (acetaminophen; codeine phosphate)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Co-codamol is effective33.33%
(5 of 15 people)
(1 of 2 people)
(0 of 1 people)
(1 of 2 people)
(1 of 4 people)
(2 of 3 people)
(0 of 4 people)
(1 of 2 people)
Ibuprofen is effective15.38%
(2 of 13 people)
(0 of 1 people)
(1 of 2 people)
(1 of 5 people)
(2 of 3 people)
(2 of 4 people)
(1 of 4 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypotensionCoronary Artery InsufficiencyAnxietyBiliary DyskinesiaPainAnxietyPerforated UlcerPain
Oesophagitis HaemorrhagicGastritisEmotional DistressMultiple InjuriesAnxietyDepressionOedemaAnxiety
Gastrointestinal HaemorrhageArteriosclerosis Coronary ArteryCoronary Artery StenosisStomach DiscomfortMyocardial InfarctionDyspepsiaNeuroendocrine CarcinomaNausea
HaematemesisCoronary Artery StenosisCholelithiasisGastritisDepressionScarHepatic FailureBack Pain
Duodenal UlcerGastrointestinal HaemorrhageAbdominal Pain UpperCholecystitis ChronicInjuryFlatulenceAnxiety DisorderFatigue
Gastric UlcerMyocardial InfarctionNauseaGallbladder DisorderOedema PeripheralHaematemesisGastrointestinal HaemorrhageVomiting
Swollen TongueAnxietyVomitingSmall Intestinal StenosisEmotional DistressInjuryCardiac Function Disturbance PostoperativeDyspnoea
DyspnoeaEpistaxisDepressionSmall Intestine UlcerHypertensionAbdominal DistensionCardiac FailureHeadache
Renal Failure AcutePainGeneral Physical Health DeteriorationPainPulmonary EmbolismConstipationGastric Ulcer PerforationDepression
Toxic Skin EruptionChest PainEncephalitisDrug IneffectiveMuscular WeaknessPainHaemothoraxDizziness

Drug effectiveness by gender :

Co-codamol is effective34.62%
(9 of 26 people)
(2 of 7 people)
Ibuprofen is effective23.08%
(6 of 26 people)
(3 of 7 people)

Most common drug interactions by gender * :

Back PainBone Disorder
FatiguePain In Jaw
Abdominal PainInsomnia

Drug effectiveness by age :

Co-codamol is effectiven/an/a0.00%
(0 of 1 people)
(3 of 6 people)
(4 of 17 people)
(3 of 7 people)
(0 of 10 people)
(1 of 3 people)
Ibuprofen is effectiven/an/a0.00%
(0 of 1 people)
(1 of 5 people)
(4 of 18 people)
(3 of 7 people)
(1 of 10 people)
(0 of 3 people)

Most common drug interactions by age * :

Psychomotor HyperactivityAsthmaAbdominal Pain UpperDysphagiaPulmonary EmbolismAnxietyFatiguePain
DeliriumVomitingNauseaMemory ImpairmentHeadacheBack PainHeadacheAnxiety
Myocardial InfarctionEpistaxisCholecystitis ChronicHallucinationAnxietyNauseaAnxietyDyspnoea
Skin Disorder NosHepatic Enzyme IncreasedCompleted SuicideCholecystitis ChronicChest PainCoughParaesthesiaGastrointestinal Haemorrhage
Pregnancy NosNasopharyngitisAnxietyAbnormal BehaviourDepressionBone DisorderNauseaBack Pain
Ventricular Septal Defect NosUnresponsive To StimuliInjuryHepatic FailureAbdominal PainHeadacheHiatus HerniaAbdominal Pain
Multiple Congenital AbnormalitiesArrhythmiaDeep Vein ThrombosisGait DisturbancePainEmotional DistressPlatelet Count DecreasedBone Disorder
Condition AggravatedSudden DeathPainAccidental OverdoseDeep Vein ThrombosisTooth ExtractionOedemaMalaise
Gastroenteritis NosAstheniaAbdominal PainNauseaInsomniaVomitingDepressionConfusional State

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Co-codamol and Ibuprofen?

Get connected! Join a mobile support group:
- group for people who take Co-codamol and Ibuprofen
- group for people who take Co-codamol
- group for people who take Ibuprofen

Comments from related studies:

  • From this study (3 months ago):

  • Have spondylithesis in L5 S1 and c567


  • From this study (7 months ago):

  • pretty constant nasty taste in mouth for 3 months


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Complete drug side effects:

On eHealthMe, Co-codamol (acetaminophen; codeine phosphate) is often used to treat pain. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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