Review: Coumadin and Metformin drug interactions
This review analyzes the interactions between Coumadin and Metformin. It is created by eHealthMe based on 5,715 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Coumadin (latest outcomes from 75,018 users) has active ingredients of warfarin sodium. It is often used in blood clots.
Metformin (latest outcomes from 100,457 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.
On Feb, 24, 2014: 5,715 people who reported to have interactions when taking Coumadin, Metformin are studied
Drug combinations in study:
- Coumadin (warfarin sodium)
- Metformin (metformin hydrochloride)
Most common interactions experienced by people in the use of Coumadin, Metformin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)||1,087|
|Dyspnoea (difficult or laboured respiration)||1,056|
|International Normalised Ratio Increased||458|
|Fatigue (feeling of tiredness)||457|
|Nausea (feeling of having an urge to vomit)||450|
|Cardiac Failure Congestive||431|
|Blood Glucose Increased||330|
|Renal Failure Acute (rapid kidney dysfunction)||323|
Most common interactions experienced by people in long term use of Coumadin, Metformin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)||28|
|Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)||26|
|Anaemia (lack of blood)||26|
|Dyspnoea (difficult or laboured respiration)||22|
|Renal Failure Acute (rapid kidney dysfunction)||20|
|International Normalised Ratio Increased||17|
|Lactic Acidosis (low ph in body tissues)||16|
|Cardiac Failure Congestive||12|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Diabetes mellitus
- Atrial fibrillation
- Type 2 diabetes mellitus
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Coumadin is used in:
- Metformin is used in:
Other drugs that are used to treat the same conditions:
- Coumadin alternatives:
- Metformin alternatives:
Comments from related studies:
From this study (2 months ago):
From this study (3 months ago):
From this study (4 months ago):
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about 3 months ago Doctor suggested increasing niacin from 1,000 mg to 1500 daily. Now on Tuesday last, I started with left sciaticia discomfort. I just thought it was a pinched nerve. Will be going to see primary care doctor this week.
Items in section 3 are currently under evaluation. Most began to emerge, subtly, approximately 11 years ago and have intensified over the past 2-3 years. Myelomalacia involving a 9.5-cm segment of the posterior column of the spinal cord was demonstrated on MRI 2 weeks ago.
Can you answer these questions (what is this?):
- By brodie: Can i use coumadin and white tea
I take Coumadin for blood clot in lung. I drink 2 cups of white tea a day. Is this okay?
- By Helen: Can metformin cause face pain ?
I have had face and jaw pain since starting to take Metformin. Also muscle pain and headaches. I am taking this drug for metabolic syndrome and wonder if it has lowered my blood sugar too much. I feel weird on it. This my 3rd week on it. I took half a pill with breakfast for 2 weeks and now am takin ...
- By DLHELLE: Should i stop taking warfarin 11 years after mesenteric clot
I Hate taking drugs period. I had a Mesenteric Clot 11 years ago, and have been on Warfarin ever since. I take 9mg, a day to keep my INR between 2.0-3.0. They found Factor V Hetro, and Protein C Resistance also. I had many surgeries prior, like C-Sections, Gall Bladder, Shoulder etc, with absolut ...
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- By MadMax: Mental or emotional symptoms of warfarin sodium
Took Coumadin or Warfarin sodium for 18 years it introduced some strange behaviors causing the people around me to think it was caused by the small stroke I had (why I was put on Coumadin). I was switched to Xarelto and within a few days I could remember the things I had been doing and thinking abo ...
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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