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Review: Coumadin and Metformin

This review analyzes the effectiveness and drug interactions between Coumadin and Metformin. It is created by eHealthMe based on reports of 5,993 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Coumadin and Metformin >>>

What are the drugs

Coumadin (what 75,068 Coumadin users reported?) has active ingredients of warfarin sodium. It is used in blood clots.

Metformin (what 100,748 Metformin users reported?) has active ingredients of metformin hydrochloride. It is used in diabetes.

On Aug, 29, 2014: 5,993 people who take Coumadin, Metformin are studied

Coumadin, Metformin outcomes

Drug combinations in study:
- Coumadin (warfarin sodium)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Coumadin is effective0.00%
(0 of 2 people)
22.22%
(4 of 18 people)
62.50%
(5 of 8 people)
57.89%
(11 of 19 people)
62.50%
(10 of 16 people)
68.75%
(11 of 16 people)
76.47%
(13 of 17 people)
0.00%
(0 of 1 people)
Metformin is effective0.00%
(0 of 3 people)
62.50%
(5 of 8 people)
44.44%
(4 of 9 people)
42.86%
(6 of 14 people)
47.37%
(9 of 19 people)
53.33%
(16 of 30 people)
61.54%
(8 of 13 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
International Normalised Ratio IncreasedInternational Normalised Ratio IncreasedDizzinessPainAnaemiaDizzinessRenal Failure AcuteDyspnoea
Atrial FibrillationAstheniaRenal Failure AcuteAnaemiaRenal Failure AcuteDepressionMental Status ChangesAtrial Fibrillation
DyspnoeaConfusional StateDyspnoeaRectal HaemorrhageLactic AcidosisCerebrovascular AccidentBradycardiaInternational Normalised Ratio Increased
NauseaDepressionFlushingDeep Vein ThrombosisMyocardial InfarctionCoronary Artery DiseaseMetabolic AcidosisNausea
Myocardial InfarctionCellulitisDiabetic RetinopathyChest PainInternational Normalised Ratio IncreasedHeadacheSomnolenceCardiac Failure Congestive
Blood Urea IncreasedDeep Vein ThrombosisCoughAbdominal Pain LowerAtrial FibrillationCardiac Failure CongestiveLactic AcidosisPain
Abdominal PainCerebral InfarctionAtrial FlutterEmotional DistressFallMyelodysplastic SyndromeComaFatigue
DehydrationDehydrationAortic Valve SclerosisDyspnoeaCardiac Failure CongestiveChest DiscomfortCardiogenic ShockDizziness
Hypocoagulable StateUrinary Tract InfectionAtrial FibrillationGeneral Physical Health DeteriorationMelaenaArthropathyAnuriaBlood Glucose Increased
Pulmonary EmbolismEmotional DistressMyalgiaMyocardial InfarctionDiarrhoeaAnxietyCoagulopathyRenal Failure Acute

Drug effectiveness by gender :

FemaleMale
Coumadin is effective48.28%
(14 of 29 people)
58.82%
(40 of 68 people)
Metformin is effective46.88%
(15 of 32 people)
50.77%
(33 of 65 people)

Most common drug interactions by gender * :

FemaleMale
NauseaAtrial Fibrillation
International Normalised Ratio IncreasedDyspnoea
DyspnoeaCardiac Failure Congestive
PainInternational Normalised Ratio Increased
Atrial FibrillationFatigue
Cardiac Failure CongestiveDizziness
FatiguePain
Blood Glucose IncreasedNausea
FallRenal Failure Acute
AstheniaAsthenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Coumadin is effectiven/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 8 people)
20.00%
(1 of 5 people)
27.66%
(13 of 47 people)
37.14%
(39 of 105 people)
Metformin is effectiven/an/an/a0.00%
(0 of 1 people)
37.50%
(3 of 8 people)
50.00%
(3 of 6 people)
24.00%
(12 of 50 people)
30.00%
(30 of 100 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Muscular Weaknessn/aPulmonary EmbolismDeep Vein ThrombosisDeep Vein ThrombosisFatigueAtrial FibrillationAtrial Fibrillation
TremorDeep Vein ThrombosisAnxietyPulmonary EmbolismPainCardiac Failure CongestiveInternational Normalised Ratio Increased
Atrial FibrillationCholelithiasisMental DisorderPainDyspnoeaNauseaDyspnoea
Neoplasm MalignantPain In ExtremityInjuryAnxietyNauseaMyocardial InfarctionNausea
Thrombophlebitis SuperficialOedema PeripheralPainType 2 Diabetes MellitusMyocardial InfarctionDyspnoeaCardiac Failure Congestive
Cerebrovascular AccidentHypercoagulationPain In ExtremityPain In ExtremityDiabetes MellitusInternational Normalised Ratio IncreasedDizziness
Throat TightnessCholecystitis ChronicUrinary Tract InfectionDeep Vein ThrombosisOedema PeripheralFatigue
Menstrual DisorderPulmonary EmbolismInjuryPain In ExtremityRenal Failure AcuteRenal Failure Acute
DyspnoeaThrombosisMalaiseInternational Normalised Ratio IncreasedPainAsthenia
Chest PainType 2 Diabetes MellitusDysphagiaBack PainRenal FailureFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Coumadin and Metformin
- group for people who take Coumadin
- group for people who take Metformin

Comments from related studies:

  • From this study (1 month ago):

  • This is a recent development after having been on these drugs for years, with the exception of the cefepime antibiotic. Recently added the ativan to help with the nervousness and shaking. Was in hospital for 10 days for surgery for a pseudomonaeus infection in leg and a rehab facility for 20 days after that, and then the shaking started.

    Reply

  • From this study (3 months ago):

  • Three months status post craniotomy for clot evacuation and subsequent refractory seizures and deep vein thrombosis. History of laminectomy and fusion 30 years ago of L4-5-S1. Symptoms of leg weakness increasing in the last few days.

    Reply

  • From this study (4 months ago):

  • Mitral Valve replacement surgery 3 years ago

    Reply

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Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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