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Review: taking Coumadin and Metformin together

Summary: drug interactions are reported among people who take Coumadin and Metformin together.

This review analyzes the effectiveness and drug interactions between Coumadin and Metformin. It is created by eHealthMe based on reports of 6,000 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from 75,111 Coumadin users)

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from 101,000 Metformin users)

On Mar, 2, 2015: 6,000 people who take Coumadin, Metformin are studied

Coumadin, Metformin outcomes

Drug combinations in study:
- Coumadin (warfarin sodium)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Coumadin is effective0.00%
(0 of 2 people)
26.32%
(5 of 19 people)
62.50%
(5 of 8 people)
60.00%
(12 of 20 people)
62.50%
(10 of 16 people)
70.59%
(12 of 17 people)
76.47%
(13 of 17 people)
0.00%
(0 of 1 people)
Metformin is effective0.00%
(0 of 3 people)
62.50%
(5 of 8 people)
44.44%
(4 of 9 people)
40.00%
(6 of 15 people)
50.00%
(10 of 20 people)
56.25%
(18 of 32 people)
61.54%
(8 of 13 people)
0.00%
(0 of 1 people)

Drug effectiveness by gender :

FemaleMale
Coumadin is effective50.00%
(15 of 30 people)
60.00%
(42 of 70 people)
Metformin is effective48.48%
(16 of 33 people)
51.47%
(35 of 68 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Coumadin is effectiven/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 8 people)
20.00%
(1 of 5 people)
27.66%
(13 of 47 people)
38.18%
(42 of 110 people)
Metformin is effectiven/an/an/a0.00%
(0 of 1 people)
37.50%
(3 of 8 people)
50.00%
(3 of 6 people)
24.00%
(12 of 50 people)
31.13%
(33 of 106 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
International Normalised Ratio IncreasedInternational Normalised Ratio IncreasedDizzinessPainAnaemiaDizzinessRenal Failure AcuteDyspnoea
Atrial FibrillationAstheniaRenal Failure AcuteAnaemiaRenal Failure AcuteCerebrovascular AccidentBradycardiaAtrial Fibrillation
DyspnoeaConfusional StateDyspnoeaRectal HaemorrhageLactic AcidosisDepressionMental Status ChangesInternational Normalised Ratio Increased
NauseaCerebral InfarctionFlushingDeep Vein ThrombosisMyocardial InfarctionHeadacheMetabolic AcidosisNausea
Myocardial InfarctionDeep Vein ThrombosisDiabetic RetinopathyChest PainInternational Normalised Ratio IncreasedCardiac Failure CongestiveSomnolenceCardiac Failure Congestive
Blood Urea IncreasedCellulitisCoughAbdominal Pain LowerAtrial FibrillationCoronary Artery DiseaseAnuriaPain
Abdominal PainDehydrationAtrial FlutterEmotional DistressFallMyelodysplastic SyndromeLactic AcidosisFatigue
DehydrationDepressionAortic Valve SclerosisDyspnoeaCardiac Failure CongestiveAnaemiaCoagulopathyDizziness
Hypocoagulable StateUrinary Tract InfectionAtrial FibrillationGeneral Physical Health DeteriorationMelaenaDiabetes MellitusComaBlood Glucose Increased
Pulmonary EmbolismSedationMyalgiaMyocardial InfarctionDiarrhoeaHypertensionCardiogenic ShockRenal Failure Acute

Most common drug interactions by gender * :

FemaleMale
NauseaAtrial Fibrillation
International Normalised Ratio IncreasedDyspnoea
DyspnoeaCardiac Failure Congestive
Atrial FibrillationInternational Normalised Ratio Increased
PainFatigue
Cardiac Failure CongestiveDizziness
FatiguePain
Blood Glucose IncreasedNausea
FallRenal Failure Acute
AstheniaAsthenia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Muscular Weaknessn/aPulmonary EmbolismDeep Vein ThrombosisDeep Vein ThrombosisFatigueAtrial FibrillationAtrial Fibrillation
TremorDeep Vein ThrombosisInjuryPulmonary EmbolismPainCardiac Failure CongestiveInternational Normalised Ratio Increased
Atrial FibrillationCholelithiasisMental DisorderPainDyspnoeaNauseaDyspnoea
Neoplasm MalignantPain In ExtremityPainAnxietyNauseaMyocardial InfarctionNausea
Thrombophlebitis SuperficialOedema PeripheralCholecystitis ChronicType 2 Diabetes MellitusMyocardial InfarctionDyspnoeaCardiac Failure Congestive
Cerebrovascular AccidentHypercoagulationPulmonary EmbolismPain In ExtremityDiabetes MellitusInternational Normalised Ratio IncreasedDizziness
Throat TightnessAnxietyUrinary Tract InfectionDeep Vein ThrombosisOedema PeripheralFatigue
Menstrual DisorderPain In ExtremityInjuryPain In ExtremityRenal Failure AcuteRenal Failure Acute
DyspnoeaType 2 Diabetes MellitusMalaiseInternational Normalised Ratio IncreasedPainAsthenia
Chest PainThrombosisDysphagiaBack PainRenal FailureFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Coumadin and Metformin on

Do you take Coumadin and Metformin?

You are not alone! Join a related mobile support group:
- support group for people who take Coumadin and Metformin
- support group for people who take Coumadin
- support group for people who take Metformin

Can you answer these questions (Ask a question):

More questions for: Coumadin, Metformin

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More reviews for: Coumadin, Metformin

Comments from related studies:

  • From this study (6 days ago):

  • Had a a fid ablation 2 weeks ago. Family Dr. Wanted blood sugar lower so added januvia. After the first day heart rate was up about 20 bears per minute, from 65 to 85. Second day woke up with afib. Went away within the first half hour. Returned about 12:30 and back to normal at 1:40pm. Back at 2:10 and ok by 3:18. Had instances of heart skipping a beat and pounding till about 8:30p.m. Went to bed about 9:30 no more afib or palpitations through the night and morning. Skipped my januvia so far today and am ok.

    Reply

  • From this study (8 months ago):

  • This is a recent development after having been on these drugs for years, with the exception of the cefepime antibiotic. Recently added the ativan to help with the nervousness and shaking. Was in hospital for 10 days for surgery for a pseudomonaeus infection in leg and a rehab facility for 20 days after that, and then the shaking started.

    Reply

  • From this study (10 months ago):

  • Three months status post craniotomy for clot evacuation and subsequent refractory seizures and deep vein thrombosis. History of laminectomy and fusion 30 years ago of L4-5-S1. Symptoms of leg weakness increasing in the last few days.

    Reply

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Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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