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Review: Coumadin and Metformin

This review analyzes the effectiveness and drug interactions between Coumadin and Metformin. It is created by eHealthMe based on 5,873 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 27, 2014: 5,873 people who reported to have interactions when taking Coumadin, Metformin are studied

Trend of Coumadin, Metformin's drug interactions, side effects and effectiveness reports (4942044)

Drug combinations in study:
- Coumadin (warfarin sodium)
- Metformin (metformin hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Coumadin, Metformin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)1,454
Dyspnoea (difficult or laboured respiration)1,450
Anxiety1,112
Pain670
Nausea (feeling of having an urge to vomit)597
Fatigue (feeling of tiredness)596
Dizziness576
Cardiac Failure Congestive570
International Normalised Ratio Increased554
Renal Failure Acute (rapid kidney dysfunction)464

Most common interactions experienced by people in long term use of Coumadin, Metformin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anaemia (lack of blood)42
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)42
Bradycardia (abnormally slow heart action)36
Anxiety34
Renal Failure Acute (rapid kidney dysfunction)33
International Normalised Ratio Increased21
Toxicity To Various Agents (poisoning due to various agents)18
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)18
Dizziness17
Lactic Acidosis (low ph in body tissues)16

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Coumadin0.00%10.00%25.00%45.00%20.00%
Metformin0.00%33.33%19.05%38.10%9.52%

Top conditions involved for these people * :

  1. Diabetes mellitus
  2. Atrial fibrillation
  3. Hypertension
  4. Type 2 diabetes mellitus
  5. Pain

Top co-used drugs for these people * :

  1. Glucophage
  2. Lasix
  3. Digoxin
  4. Aspirin
  5. Furosemide

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Coumadin, Metformin

You can also:

Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Metformin (metformin hydrochloride) is often used to treat type 2 diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 months ago):

  • Swelling develops quickly and is usually accompanied by itching and occasional rash. Swelling begins to dissipate after 4-5 hours. It is totally random - two weeks without any swelling, then 3-4 days with itching and swelling at different sites.

    Reply

  • From this study (4 months ago):

  • Family history of stroke on Father and Uncles side. Brief thyroid problem. History-- infrequent use of anti-depressants during teens to 30's---Stelazine, Mellaril. My Fathers Mother was treated for Manic-depression after 30-82yo.

    Reply

  • From this study (5 months ago):

  • about 3 months ago Doctor suggested increasing niacin from 1,000 mg to 1500 daily. Now on Tuesday last, I started with left sciaticia discomfort. I just thought it was a pinched nerve. Will be going to see primary care doctor this week.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Can coumadin cause insomnia
    i just had carpal tunnel surgery had to stop coumadin and inject myself with lovenox and now i am back on the coumadin along with the lovenox but my pro time is still low and i was told to still take the needles along with the coumadin i also all of a sudden have insomnia I am a 66 year old ...

  • How does a scorpion sting affect someone on coumadin?
    20 years ago, I had a hysterectomy. Complications set in and I ended up with Deep Thrombosis, (Giant Blood Clot)! As a result from that, a year later I ended up with an 8-10 inch stent in my upper body off of my left leg to keep the blood flow open to and from my leg and heart! I was told I would b ...

  • Is coughing and gagging associated with hiatal hernia
    Coughing, gagging and extreme diarrhea have been evident since the introduction of warfarin/coumadin. Could these symptoms be caused by this bolld thinner?

More questions for: Coumadin, Metformin

You may be interested at these reviews (what is this?):

  • Metformin changes in mentrual cycle
    At age 55, I started to enter menopause. When it began to taper off a couple of years ago, only one ovary was functioning, and my periods lasted only 1-2 days with minimal flow. Hadn't had a period in 4 months. Still had some PMS symptoms, but no flow. Was prescribed Metformin for pre-diabetes. My ...

  • Metformin induced psoriatiform drug eruption
    I'm a medical professional and I found psoratiform drug eruptions on my glans penis after taking metformin. This is the second time it has come and made me investigate the scenario myself. Lesions are scaly erythematous lesions and I am currently using low potency topical steroids after discontinuin ...

  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

More reviews for: Coumadin, Metformin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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